Tags Archives: metabolomics

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Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass

Abstract Background We sought to determine differences in the circulating metabolic profile of infants with or without acute kidney injury (AKI) following cardiothoracic surgery with cardiopulmonary bypass (CPB). Methods We..

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Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis

Abstract Calcific aortic valve disease sits at the confluence of multiple world-wide epidemics of aging, obesity, diabetes, and renal dysfunction, and its prevalence is expected to nearly triple over the..

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Identification of Plasma Metabolites Prognostic of Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass

Abstract Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass, but early detection of postoperative AKI remains challenging. Protein biomarkers predict AKI excellently in homogeneous cohorts but are..

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