Tags Archives: Mechanical ventilation

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Flow-controlled versus pressure-controlled ventilation in cardiac surgery with cardiopulmonary bypass – A single-center, prospective, randomized, controlled trial

Abstract Study objective Multifactorial comparison of flow-controlled ventilation (FCV) to standard of pressure-controlled ventilation (PCV) in terms of oxygenation in cardiac surgery patients after chest closure. Design Prospective, non-blinded, randomized,..

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Influenza Season and Outcome After Elective Cardiac Surgery: An Observational Cohort Study

Abstract Background An asymptomatic  during cardiac surgery could lead to pulmonary complications and increased mortality. For , testing for  before surgery or vaccination could reduce the number of these pulmonary complications. The aim..

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Mechanical Ventilation during ECMO: Best Practices

Abstract Adults and children who require extracorporeal membrane oxygenation for respiratory failure remain at risk for ongoing lung injury if ventilator management is not optimized. This review serves as a..

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Association between pediatric intensive care mortality and mechanical ventilation settings during extracorporeal membrane oxygenation for pediatric acute respiratory distress syndrome

Abstract The main objective of this study was to describe the current mechanical ventilation (MV) settings during extracorporeal membrane oxygenation (ECMO) for pediatric acute respiratory distress syndrome (P-ARDS) in six..

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Physiology-guided management of hemodynamics in acute respiratory distress syndrome

Abstract Skillfully implemented mechanical ventilation (MV) may prove of immense benefit in restoring physiologic homeostasis. However, since hemodynamic instability is a primary factor influencing mortality in acute respiratory distress syndrome..

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Setting and Monitoring of Mechanical Ventilation During Venovenous ECMO

Introduction In patients with the acute respiratory distress syndrome(ARDS), mechanical ventilation can cause ventilator-induced lung injury (VILI) through multiple mecha-nisms, including volutrauma, barotrauma, atelectrauma,myotrauma, and biotrauma [1]. In the most..

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Optimal positive end-expiratory pressure reduces right ventricular dysfunction in COVID-19 patients on venovenous extracorporeal membrane oxygenation: A retrospective single-center study

Abstract While mechanical ventilation practices on venovenous extracorporeal membrane oxygenation (VV ECMO) are variable, most institutions utilize a lung rest strategy utilizing relatively low positive end-expiratory pressure (PEEP). The effect..

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Role of nebulized heparin in mechanically ventilated critically ill patients

Abstract Background  Mechanical ventilation is a technique for supporting or substituting respiration. Fibrin deposition in the pulmonary microcirculation and alveolar sacs (hyaline membrane generation) is a major inflammatory route of..

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Liberation from Mechanical Ventilation Before Decannulation from Venovenous Extracorporeal Life Support in Severe COVID-19 Acute Respiratory Distress Syndrome

Abstract The coronavirus disease 2019 (COVID-19) pandemic has been associated with the significant use of venovenous extracorporeal membrane oxygenation (VVECMO) globally. Identifying strategies to optimize care is essential to improving..

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Awake extracorporeal life support and physiotherapy in adult patients: A systematic review of the literature

Abstract Objective The Awake Extracorporeal Life Support (ECLS) practice combined with physiotherapy is increasing. However, available evidence for this approach is limited, with unclear indications on timing, management, and protocols...

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Mechanical Ventilation during ECMO: Lessons from Clinical Trials and Future Prospects

Abstract Acute Respiratory Distress Syndrome (ARDS) accounts for 10% of ICU admissions and affects 3 million patients each year. Despite decades of research, it is still associated with one of..

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Venovenous extracorporeal membrane oxygenation in patients with acute covid-19 associated respiratory failure: comparative effectiveness study

Abstract Objective To estimate the effect of extracorporeal membrane oxygenation (ECMO) compared with conventional mechanical ventilation on outcomes of patients with covid-19 associated respiratory failure. Design Observational study. Setting 30 countries across five..

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Association of Ventilator Settings with Mortality in Pediatric Patients Treated with Extracorporeal Life Support for Respiratory Failure

Abstract Extracorporeal life support (ECLS) is a treatment for acute respiratory failure that can provide extracorporeal gas exchange, allowing lung rest. However, while most patients remain mechanically ventilated during ECLS,..

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The association of modifiable mechanical ventilation settings, blood gas changes and survival on extracorporeal membrane oxygenation for cardiac arrest

Abstract Research question Given the relative independence of ventilator settings from gas exchange and plasticity of blood gas values during extracorporeal cardiopulmonary resuscitation (ECPR), do mechanical ventilation parameters and blood..

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Mechanical ventilation during cardiopulmonary bypass in neonates improves postoperative outcome

Abstract   OBJECTIVES Cardiopulmonary bypass generates a systemic inflammatory response. This inflammatory response is reduced if patients are ventilated during bypass, as evidenced by lower levels of postoperative circulating inflammatory..

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Effect of ventilation strategy during cardiopulmonary bypass on postoperative pulmonary complications after cardiac surgery: a randomized clinical trial

Abstract Background To determine whether maintaining ventilation during cardiopulmonary bypass (CPB) with a different fraction of inspired oxygen (FiO2) had an impact on the occurrence of postoperative pulmonary complications (PPCs)...

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Is airway pressure release ventilation, a better primary mode of post-operative ventilation for adult patients undergoing open heart surgery? A…

Abstract Context: Cardiopulmonary bypass (CPB) induced acute lung injury is accounted for most of the post-operative pulmonary dysfunction which leads to decreased compliance and hypoxemia. Airway Pressure Release Ventilation (APRV) as..

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Efficacy of Intraoperative Hemodynamic Optimization Using FloTrac/EV1000 Platform for Early Goal-Directed Therapy to Improve Postoperative Outcomes in Patients Undergoing Coronary…

Abstract Purpose:  Early goal-directed therapy (EGDT) using the FloTrac system reportedly improved postoperative outcomes among high-risk patients undergoing non-cardiac surgery. This study’s objective was to evaluate the FloTrac/EV1000 platform’s efficacy..

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Management of Adult Patients Supported with Venovenous Extracorporeal Membrane Oxygenation (VV ECMO): Guideline from the Extracorporeal Life Support Organization (ELSO)

Abstract The use of venovenous extracorporeal membrane oxygenation (VV ECMO) among adults is rapidly increasing worldwide. By 2020, the Extracorporeal Life Support Organization (ELSO) Registry had recorded >24,000 cases of..

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ECMO Assistance during Mechanical Ventilation: Effects Induced on Energetic and Haemodynamic Variables

Abstract Background and Objective Simulation in  may help clinicians understand the important events occurring during  and . During the COVID-19 pandemic, a significant number of patients have required hospital admission to tertiary referral..

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Prone position in intubated, mechanically ventilated patients with COVID‑19: a multi‑centric study of more than 1000 patients

Abstract Background: Limited data are available on the use of prone position in intubated, invasively ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to investigate the use..

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Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

Abstract Background:  The mortality of critically ill patients with COVID-19 is high, particularly among those receiving mechanical ventilation (MV). Despite the high number of patients treated worldwide, data on respiratory..

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Management of Mechanical Ventilation During Extracorporeal Membrane Oxygenation

Abstract This chapter explores the best practices of mechanical ventilation during extracorporeal membrane oxygenation (ECMO) through a detailed discussion of the physiologic theory and clinical evidence. Future areas of study..

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Decreases in Mixed Venous Blood O2 Saturation in Cardiac Surgery Patients Following Extubation

Abstract Background: Decreases in mixed venous O2 saturation (SvO2) have been reported to occur in postcardiac surgery patients during weaning from mechanical ventilation. Our aim was to establish whether the physiological..

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Efficacy and safety of inhaled anaesthetic for postoperative sedation during mechanical ventilation in adult cardiac surgery patients: a systematic review…

Abstract The aim was to evaluate the efficacy and safety of volatile anaesthetic for postoperative sedation in adult cardiac surgery patients through a systematic review and meta-analysis. We retrieved randomized..

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Takotsubo Cardiomyopathy Following Cardiac Surgery

Abstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..

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Extracorporeal Membrane Oxygenation Support in Severe COVID-19

Abstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..

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Protection strategies during cardiopulmonary bypass

Abstract Purpose of review  To provide an update of research findings regarding the protection strategies utilized for patients undergoing cardiopulmonary bypass (CPB), including perioperative ventilatory strategies, different anesthetic regimens, and..

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Pro: Mechanical Ventilation Should Be Continued During Cardiopulmonary Bypass

POSTOPERATIVE PULMONARY dysfunction, a known complication after cardiac surgery, is associated with significant morbidity and mortality. Pulmonary complications include hypoxemia; increased work of breathing; atelectasis; pneumonia; and in 2% to..

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