Abstract Study objective Multifactorial comparison of flow-controlled ventilation (FCV) to standard of pressure-controlled ventilation (PCV) in terms of oxygenation in cardiac surgery patients after chest closure. Design Prospective, non-blinded, randomized,..
Read MoreAbstract Background An asymptomatic during cardiac surgery could lead to pulmonary complications and increased mortality. For , testing for before surgery or vaccination could reduce the number of these pulmonary complications. The aim..
Read MoreAbstract Adults and children who require extracorporeal membrane oxygenation for respiratory failure remain at risk for ongoing lung injury if ventilator management is not optimized. This review serves as a..
Read MoreAbstract The main objective of this study was to describe the current mechanical ventilation (MV) settings during extracorporeal membrane oxygenation (ECMO) for pediatric acute respiratory distress syndrome (P-ARDS) in six..
Read MoreAbstract Skillfully implemented mechanical ventilation (MV) may prove of immense benefit in restoring physiologic homeostasis. However, since hemodynamic instability is a primary factor influencing mortality in acute respiratory distress syndrome..
Read MoreIntroduction In patients with the acute respiratory distress syndrome(ARDS), mechanical ventilation can cause ventilator-induced lung injury (VILI) through multiple mecha-nisms, including volutrauma, barotrauma, atelectrauma,myotrauma, and biotrauma [1]. In the most..
Read MoreAbstract While mechanical ventilation practices on venovenous extracorporeal membrane oxygenation (VV ECMO) are variable, most institutions utilize a lung rest strategy utilizing relatively low positive end-expiratory pressure (PEEP). The effect..
Read MoreAbstract Background Mechanical ventilation is a technique for supporting or substituting respiration. Fibrin deposition in the pulmonary microcirculation and alveolar sacs (hyaline membrane generation) is a major inflammatory route of..
Read MoreAbstract The coronavirus disease 2019 (COVID-19) pandemic has been associated with the significant use of venovenous extracorporeal membrane oxygenation (VVECMO) globally. Identifying strategies to optimize care is essential to improving..
Read MoreAbstract Objective The Awake Extracorporeal Life Support (ECLS) practice combined with physiotherapy is increasing. However, available evidence for this approach is limited, with unclear indications on timing, management, and protocols...
Read MoreAbstract Acute Respiratory Distress Syndrome (ARDS) accounts for 10% of ICU admissions and affects 3 million patients each year. Despite decades of research, it is still associated with one of..
Read MoreAbstract Objective To estimate the effect of extracorporeal membrane oxygenation (ECMO) compared with conventional mechanical ventilation on outcomes of patients with covid-19 associated respiratory failure. Design Observational study. Setting 30 countries across five..
Read MoreAbstract Extracorporeal life support (ECLS) is a treatment for acute respiratory failure that can provide extracorporeal gas exchange, allowing lung rest. However, while most patients remain mechanically ventilated during ECLS,..
Read MoreAbstract Research question Given the relative independence of ventilator settings from gas exchange and plasticity of blood gas values during extracorporeal cardiopulmonary resuscitation (ECPR), do mechanical ventilation parameters and blood..
Read MoreAbstract OBJECTIVES Cardiopulmonary bypass generates a systemic inflammatory response. This inflammatory response is reduced if patients are ventilated during bypass, as evidenced by lower levels of postoperative circulating inflammatory..
Read MoreAbstract Background To determine whether maintaining ventilation during cardiopulmonary bypass (CPB) with a different fraction of inspired oxygen (FiO2) had an impact on the occurrence of postoperative pulmonary complications (PPCs)...
Read MoreAbstract Context: Cardiopulmonary bypass (CPB) induced acute lung injury is accounted for most of the post-operative pulmonary dysfunction which leads to decreased compliance and hypoxemia. Airway Pressure Release Ventilation (APRV) as..
Read MoreAbstract Purpose: Early goal-directed therapy (EGDT) using the FloTrac system reportedly improved postoperative outcomes among high-risk patients undergoing non-cardiac surgery. This study’s objective was to evaluate the FloTrac/EV1000 platform’s efficacy..
Read MoreAbstract The use of venovenous extracorporeal membrane oxygenation (VV ECMO) among adults is rapidly increasing worldwide. By 2020, the Extracorporeal Life Support Organization (ELSO) Registry had recorded >24,000 cases of..
Read MoreAbstract Background and Objective Simulation in may help clinicians understand the important events occurring during and . During the COVID-19 pandemic, a significant number of patients have required hospital admission to tertiary referral..
Read MoreAbstract Background: Limited data are available on the use of prone position in intubated, invasively ventilated patients with Coronavirus disease-19 (COVID-19). Aim of this study is to investigate the use..
Read MoreAbstract Background: The mortality of critically ill patients with COVID-19 is high, particularly among those receiving mechanical ventilation (MV). Despite the high number of patients treated worldwide, data on respiratory..
Read MoreAbstract This chapter explores the best practices of mechanical ventilation during extracorporeal membrane oxygenation (ECMO) through a detailed discussion of the physiologic theory and clinical evidence. Future areas of study..
Read MoreAbstract Background: Decreases in mixed venous O2 saturation (SvO2) have been reported to occur in postcardiac surgery patients during weaning from mechanical ventilation. Our aim was to establish whether the physiological..
Read MoreAbstract The aim was to evaluate the efficacy and safety of volatile anaesthetic for postoperative sedation in adult cardiac surgery patients through a systematic review and meta-analysis. We retrieved randomized..
Read MoreAbstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..
Read MoreAbstract Background Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal..
Read MoreAbstract Purpose of review To provide an update of research findings regarding the protection strategies utilized for patients undergoing cardiopulmonary bypass (CPB), including perioperative ventilatory strategies, different anesthetic regimens, and..
Read MorePOSTOPERATIVE PULMONARY dysfunction, a known complication after cardiac surgery, is associated with significant morbidity and mortality. Pulmonary complications include hypoxemia; increased work of breathing; atelectasis; pneumonia; and in 2% to..
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