Tags Archives: Left ventricular assist device

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Effect of cardiac arrest…

Abstract OBJECTIVES Some patients who undergo continuous-flow left ventricular assist device (CF-LVAD) implantation require concomitant procedures that can be performed with or without cardiac arrest under aortic cross-clamping (AXC). Procedures..

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Clinical and In Vitro…

Background Recent data suggest that  contributes to  (LVAD) , but the mechanism is unknown. In a clinical study, we measured plasma free hemoglobin (pfHgb) and the incidence of LVAD thrombosis. In an in..

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Continuous-Flow Left Ventricular Assist…

Background Having a preoperative small  (LV) has been associated with higher complication and mortality rates after  (LVAD) implantation; however, the outcomes after continuous-flow LVAD implantation have not been well studied. This is..

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Late-onset right ventricular dysfunction…

Abstract Background Right heart failure (RHF) is a serious post-operative complication of left ventricular assist device (LVAD) implantation, with significant morbidity and mortality. Many clinical, hemodynamic and laboratory variables have..

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Transcatheter Aortic Valve Replacement…

SURGICAL AORTIC VALVE replacement historically has been the standard of care for patients with severe, symptomatic aortic stenosis. However, up to one-third of patients with symptomatic aortic stenosis are not..

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Mycobacterium chimaera left ventricular…

Abstract A global outbreak of invasive Mycobacterium chimaera infections after cardiac surgery has recently been linked to bioaerosols from contaminated heater‐cooler units. The majority of cases have occurred after valvular surgery or..

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Electrostatic Discharge Causing Pump…

Abstract  (LVADs) improve symptoms and outcomes in advanced heart failure. Although device malfunction has decreased significantly with later generation LVADs, it has not been eliminated. We describe the clinical course..

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Reverse Remodeling With Left…

Abstract This review provides a comprehensive overview of the past 25+ years of research into the development of left ventricular assist device (LVAD) to improve clinical outcomes in patients with..

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Pre-transplant heart disease etiology…

Abstract Left ventricular assist devices (LVAD) have become an established mode of treatment in bridging patients with advanced heart failure to cardiac transplantation. In certain groups of patients LVADs have..

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Percutaneous venopulmonary artery extracorporeal…

Abstract OBJECTIVES Right ventricular failure after left ventricular assist device (LVAD) insertion is associated with significant mortality and morbidity. Mechanical support options include right ventricular assist devices, venoarterial extracorporeal membrane..

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The Role of Serial…

Abstract Current guidelines recommend serial right heart catheterization (RHC) to survey pulmonary hypertension in patients awaiting heart transplant. However, the role and impact of this surveillance is unclear in patients..

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Impact of left ventricular…

Abstract Background Extracorporeal cardiopulmonary resuscitation (eCPR) is a rapidly growing treatment strategy due to increasing survival rates in selected patients. Additional left ventricular mechanical unloading, using a transfemoral micro-axial blood..

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Numerical study of the…

Abstract Left ventricular assist devices (LVADs) have been increasingly used as a therapy for patients with end-stage heart failure. However, a growing number of clinical observations have shown that LVADs..

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Use of Extracorporeal Membrane…

Abstract Background: There has been increasing use of extracorporeal membrane oxygenation (ECMO) as bridge to heart transplant (orthotopic heart transplant [OHT]) or left ventricular assist device (LVAD) over the last..

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Concept and Design of…

Abstract Cardiogenic shock is associated with high mortality. Patients often require temporary mechanical circulatory support. We aimed to develop a percutaneously implantable, assist device that unloads the left ventricle (LV)..

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PHYSIOLOGIC EFFECTS OF CONTINUOUS-FLOW…

Abstract Background Within the past ten years, continuous-flow Left Ventricular Assist Devices (LVADS) have replaced pulsatile-flow LVADs as the standard of care for both destination therapy and bridging patients to..

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Inflow cannula position as…

Abstract Background A relation between the left ventricular assist device inflow cannula (IC) malposition and pump thrombus has been reported. This study aimed to investigate if the pump position, derived..

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Impella to Unload the…

Abstract Peripheral venoarterial extracorporeal membrane oxygenation (VA ECMO) for acute cardiac failure reestablishes normal oxygen delivery and perfusion. However, VA ECMO can be limited by insufficient ventricular unloading, resulting in..

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MitraClip® procedure as bridge…

Abstract Secondary mitral valve regurgitation is a frequent consequence of left ventricular dysfunction in patients with severe heart failure. The management of this disease can be challenging since it often..

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Right Ventricular Global Longitudinal…

Abstract Early right heart failure (RHF) occurs in up to 40% of patients following left ventricular assist device (LVAD) implantation and is associated with increased morbidity and mortality. The most recent..

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Trends and Outcomes of…

Abstract As the prevalence of advanced heart failure continues to rise, treatment strategies for select patients include heart transplantation or durable left ventricular assist device (LVAD) support, both of which..

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Biological Response to Sintered…

Abstract Titanium alloys have traditionally been used in blood-contacting cardiovascular devices, including left ventricular assist devices (LVADs). However, titanium surfaces are susceptible to adverse coagulation, leading to thrombogenesis and stroke...

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Development of a non-transplant…

Abstract Introduction Although the established long-term benefit of left ventricular assist device (LVAD) therapy has led to its proliferation as destination therapy (DT), few studies have evaluated LVAD outcomes at..

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Characteristics and Outcomes of…

Abstract There are limited data on the characteristics and clinical course of fungal infections in patients on durable left ventricular assist device (LVAD) support. We sought to further characterize the..

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HeartMate left ventricular assist…

Abstract We describe three successful cases of HeartMate left ventricular assist device (LVAD; Thermo Cardiosystems, Woburn, MA, USA) implantation in patients with end-stage heart failure for long-term circulatory support. Patient..

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Left ventricular vs. biventricular…

Abstract Left ventricular assist devices (LVADs) are safer and provide better survival and better quality of life than biventricular assist devices (BVADs) but end-stage heart failure often involves both ventricles,..

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Prediction of Survival After…

Abstract Background Clinical trials inform on average efficacy, but individualized risk assessments for outcome prediction are important in guiding treatment implementation. Objectives The authors developed and validated a patient-specific risk..

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The arresting LVAD patient:…

By Stephanie Louka, MD Case scenario: Paramedics are called to the home of a 59-year-old male patient with an LVAD who was found unconscious and unresponsive by family members. He..

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Application of 1,000 fps…

Abstract Left ventricular assist device (LVAD)–induced hemodynamics are characterized by fast-moving flow with large variations in velocity, making quantitative assessments difficult with existing imaging methods. This study demonstrates the ability of..

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