Tags Archives: ischaemia/reperfusion injury

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Nicorandil attenuates ventricular dysfunction and organ injury after cardiopulmonary bypass

Abstract Background Nicorandil, an adenosine triphosphate-sensitive potassium channel agonist and nitric oxide donor, is a coronary vasodilator used to treat ischemia-induced chest pain, but it's potential cardioprotective benefits during open..

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Effects of inorganic nitrate on ischaemia-reperfusion injury after coronary artery bypass surgery

Abstract Background  (NO) is an important signalling molecule in the cardiovascular system with protective properties in ischaemia–reperfusion injury. Inorganic nitrate, an oxidation product of endogenous NO production and a constituent..

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Safety of nitric oxide added to the ECMO circuit: a pilot study in children

Abstract We describe our experience of 30 consecutive children supported with ECMO and receiving 20 ppm of nitric oxide in the oxygenator of the ECMO circuit. Administration of nitric oxide..

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Remote ischaemic preconditioning: is it a flag on the field?

Abstract Ischaemic preconditioning is one of several different techniques that have been proposed to render the heart more resistant to ischaemia/reperfusion injuries. A significant reduction of troponin release is ‘proof..

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