Abstract Objective The connection between perioperative hypothermia and the occurrence of surgical site infections (SSIs) is still not clearly established. This investigation aimed to clarify the potential link between these..
Read MoreBackground Accidental hypothermia (AH) can be caused by exposure to cold weather conditions, immersion in water, avalanche burial in snow, or indoors, mostly affecting elderly patients with multiple comorbidities., There are..
Read MoreAbstract Introduction: Indexed oxygen delivery (DO₂i) is a critical parameter in cardiopulmonary bypass (CPB) management. Traditional goal-directed perfusion (GDP) protocols use fixed DO₂i thresholds, typically derived from normothermic conditions. However,..
Read MoreAbstract Background Postoperative hypothermia seems to be a common problem in surgical patients but is easily ignored. This study aimed to identify risk factors for postoperative hypothermia in non-cardiac surgery..
Read MoreIntroduction Cardiopulmonary bypass (CPB) has transformed cardiac surgery, allowing for safe and controlled procedures on the arrested heart. However, a long-standing debate in perfusion science is whether CPB should be..
Read MoreAbstract Hypothermic oxygenated perfusion (HOPE) is an emerging technique for donor heart preservation that is currently being studied in multiple clinical trials with promising results. When compared to HOPE for..
Read MoreAbstract Severe accidental hypothermia can lead to cardiac arrest. The most efficient method of resuscitating and warming is by ECMO (Extracorporeal Membrane Oxygenation). While the convention is to use VA..
Read MoreAbstract Aim of the study Predictive factors for poor outcomes in hypothermic cardiac arrest (HCA) differ from those in normothermic out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate the..
Read MoreAbstract Shifts from deep to moderate hypothermic circulatory arrest (HCA) in aortic arch surgery necessitate an examination of their differential impacts on neurocognitive functions, especially structured verbal memory, given its..
Read MoreAbstract IMPORTANCE: Persistent hypothermia after cardiopulmonary bypass (CPB) in neonates with congenital heart defects (CHD) has been historically considered benign despite lack of evidence on its prognostic significance. OBJECTIVES: Examine..
Read MoreAbstract Aim Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has become a common intervention for patients with cardiogenic shock (CS), often complicated by cardiac arrest (CA). Moderate hypothermia (MH) has shown promise..
Read MoreAbstract Background Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS),..
Read MoreSimultaneous upper and lower body perfusion using hypothermia during thoracoabdominal aortic surgery
Abstract Background In open thoracoabdominal aortic aneurysm (TAAA) repair, we have been performing vascular reconstruction under moderate to deep hypothermia and assisted circulation using simultaneous upper and lower body perfusion...
Read MoreAbstract Objective We designed a simplified total arch reconstruction (s-TAR) technique which could be performed under mild hypothermia (30–32 °C) with distal aortic perfusion. This study aimed to compare its efficacy..
Read MoreAbstract Treatment recommendations for rewarming patients in severe accidental hypothermia with preserved spontaneous circulation have a weak evidence due to the absence of randomized clinical trials. We aimed to compare the outcomes..
Read MoreAbstract Despite venovenous or venoarterial (ECMO) being increasingly used in patients with severe syndrome, severe , and refractory cardiac arrest, mortality rates still remain high mainly because of the severity..
Read MoreAbstract Background Either deep hypothermia with circulatory arrest or hypothermic perfusion with antegrade selective cerebral perfusion is used during the Norwood procedure for hypoplastic left heart syndrome. Normothermic perfusion has..
Read MoreAbstract Advancements in cardiac arrest and post-cardiac arrest care have led to improved survival to hospital discharge. While survival to hospital discharge is an important clinical outcome, neurologic recovery is..
Read MoreAbstract BACKGROUND The evidence for temperature control for comatose survivors of cardiac arrest is inconclusive. Controversy exists as to whether the effects of hypothermia differ per the circumstances of the..
Read MoreAbstract Objective To review studies that assessed systemic hypothermia as an organ protection strategy in adults undergoing cardiac surgery with cardiopulmonary bypass. Design A systematic review and meta-analysis. Setting and..
Read MoreAbstract Accidental hypothermia with a core temperature below 28°C is associated with an increased risk of hemodynamic instability. It is difficult to predict which patients will survive with a favorable..
Read MoreAbstract Hypothermia is defined as a core body temperature of <35°C, and as body temperature is reduced the impact on physiological processes can be beneficial or detrimental. The beneficial effect..
Read MoreAbstract Zafren, Ken, Raimund Lechner, Peter Paal, Hermann Brugger, Giles Peek, and Tomasz Darocha. Induced hypothermia to as cold as 3°C in humans: Forgotten cases rediscovered. High Alt Med Biol. 22:000–000, 2021...
Read MoreAbstract Importance The optimal approach to the use of venoarterial extracorporeal membrane oxygenation (ECMO) during cardiogenic shock is uncertain. Objective To determine whether early use of moderate hypothermia (33-34 °C) compared with..
Read MoreAbstract BACKGROUND Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS In an open-label trial with blinded assessment of outcomes,..
Read MoreAbstract Importance The optimal approach to the use of venoarterial extracorporeal membrane oxygenation (ECMO) during cardiogenic shock is uncertain. Objective To determine whether early use of moderate hypothermia (33-34 °C) compared with..
Read MoreAbstract Objective To investigate the effects of different target hypothermia on the cardiovascular function and prognosis of rats after cardiopulmonary resuscitation. Methods A total of 44 male SD rats were..
Read MoreAbstract Accidental hypothermia (AH) in Mediterranean countries often is underestimated. AH should be suspected in patients also in moderate climates throughout all seasons. Compared with other countries, the mortality rate..
Read MoreAbstract Background Oxygen delivery during cardiopulmonary bypass (CPB) is closely related to postoperative acute kidney injury (AKI). The value of critical indexed oxygen delivery (DO2i) is a key indicator to..
Read MoreAbstract Aim To determine whether targeting a mean arterial pressure of 90 mmHg (MAP90) would yield improved cerebral blood flow and less ischaemia compared to MAP 60 mmHg (MAP60) with..
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