Tags Archives: hemorrhage

Perfusfind S.L.

Abstract Introduction and importance Bleeding during pregnancy or during  can cause significant morbidity and mortality for the mother and baby, this can be overcome by performing a  (C-section) and . Although blood transfusions..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a rescue therapy in patients with severe acute res‑piratory distress syndrome (ARDS) secondary to COVID‑19. While bleeding and thrombosis complicate ECMO, theseevents may..

Perfusfind S.L.

Abstract Purpose: This study aimed to assess the necessity of routine intraoperative cell salvage in liver transplantations. Methods: A total of 327 liver transplants performed between 2014 and 2016 was..

Perfusfind S.L.

Abstract Background Thrombocytopenia, hemorrhage and platelet transfusion are common in patients supportedwith venoarterial extracorporeal membrane oxygenation (VA ECMO). However, current literature is limited to smallsingle‑center experiences with high degrees of..

Perfusfind S.L.

Abstract Blood loss by hemorrhaging wounds accounts for over one-third of ∼5 million trauma fatalities worldwide every year. If not controlled in a timely manner, exsanguination can take lives within..

Perfusfind S.L.

Abstract Introduction Extracorporeal Membrane Oxygenation (ECMO) may be used in the setting of pregnancy or the peripartal period, however its utility has not been well-characterized. This study aims to give..

Perfusfind S.L.

Abstract As perioperative bleeding continues to be a major source of morbidity and mortality in cardiac surgery, the search continues for an ideal  for use in this patient population. Transfusion of..

Perfusfind S.L.

Abstract Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become an essential method for assaying hemostatic competence in liver transplantation, cardiac surgery, and most recently, trauma surgery..

Perfusfind S.L.

Abstract Massive diffuse bleeding is still a problem in cardiovascular surgery. The first line treatment is platelet concentrate transfusion, although there is still insufficient information regarding efficacy, quantity, and timing...

Perfusfind S.L.

Abstract Objectives:  To investigate platelet pathophysiology associated with pediatric extracorporeal membrane oxygenation (ECMO). Design:  Prospective observational study of neonatal and pediatric ECMO patients from September 1, 2016, to December 31,..

Perfusfind S.L.

Abstract Background Coagulopathy and following massive bleeding are complications of cardiovascular surgery, particularly occurring after procedures requiring prolonged cardiopulmonary bypass (CPB). Reliable and rapid tests for coagulopathy are desirable for..

Perfusfind S.L.

Abstract The clinical importance of viscoelastic testing in patient blood management when performing cardiovascular surgery is increasing. We aimed to examine the effect of a blood transfusion protocol including an..

Perfusfind S.L.

Abstract Objectives Recombinant factor VIIa is used off-label for refractory bleeding after cardiac surgery. This study reviewed the indications, usage rates and complications of recombinant factor VIIa. Design Retrospective case..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation is challenged by several potential complications. Adverse neurologic events such as intracranial hemorrhages, strokes, seizures, and brain death are among the most detrimental and even catastrophic..

Perfusfind S.L.

Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo hemostasis, while viscoelastic tests, thromboelastography (TEG),..

Perfusfind S.L.

Abstract Background Hemorrhagic events remain a major concern in patients under extracorporeal membrane oxygenation (ECMO) support. We tested the association between anticoagulation levels and hemorrhagic events under ECMO using anti-Xa..

Perfusfind S.L.

Abstract Background Postoperative bleeding after heart operations is still a common finding, leading to allogeneic blood products transfusion. Fibrinogen and coagulation factors deficiency are possible determinants of bleeding. The experimental..

Perfusfind S.L.

Abstract Purpose Hemorrhage is the most common cause of preventable death after trauma. Coagulopathy plays a central role in uncontrolled bleeding and is caused by multiple factors. Extracorporeal Membrane Oxygenation..

Perfusfind S.L.

Abstract Anesthesiologists may encounter patients with disseminated intravascular coagulation, a potential complication of severe sepsis or major trauma. This practical guide discusses the clinical approach, laboratory diagnosis, and current management..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) protocols generally require systemic anticoagulation with heparin to prevent circuit thrombosis. The prevalence, risk factors, and outcomes of heparin resistance in this setting are ill-defined. To better..

Perfusfind S.L.

Abstract Background Obesity is suggested to reduce postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) but perioperative hemostasis variations have not been studied. Therefore, we investigated the..

Perfusfind S.L.

Abstract The use of extracorporeal circulation for cardiac surgery and extracorporeal life support poses tremendous challenges to the hemostatic equilibrium given its diametric tendency to trigger hyper‐ and hypocoagulopathy. The..

Perfusfind S.L.

Abstract There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial..

Perfusfind S.L.

Abstract Background Protamine neutralization is an essential step for the safe use and inactivation of the unfractionated heparin (UFH) that is widely employed in surgical and non-surgical procedures involving extracorporeal..

Perfusfind S.L.

Abstract BACKGROUND Sugammadex, which is used to reverse rocuronium-induced neuromuscular blockade, has a limited and transient effect on activated partial thromboplastin time and prothrombin time. However, no data are available..

Perfusfind S.L.

Abstract Background Protamine neutralization is an essential step for the safe use and inactivation of the unfractionated heparin (UFH) that is widely employed in surgical and non‐surgical procedures involving extracorporeal..

Perfusfind S.L.

Abstract Editor’s Perspective What We Already Know about This Topic Major bleeding can occur during cardiac surgery. Although different scoring systems exist, the assessment of bleeding can be variable, and..

Perfusfind S.L.

Abstract Although advances in knowledge and technology have improved outcomes in surgical cardiac patients over the last decade, complications following cardiac operations still remain to be potentially fatal. Gastrointestinal complications,..