Abstract Importance Acute normovolemic hemodilution (ANH) is a well-known blood conservation technique, yet its adoption in the US remains low (<20%), and cardiac surgery remains the largest consumer of blood components...
Read MoreAbstract Background Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic hemodilution [ANH]) is a blood-conservation technique..
Read MoreIntroduction Cardiopulmonary bypass (CPB) introduces significant alterations in blood composition due to the priming solution, fluid shifts, and extracorporeal circulation. Hemodilution and hemoconcentration represent two opposing strategies, each with distinct..
Read MoreAbstract Background Minimizing the use of blood component can reduce known and unknown risks, preserve blood bank resources, and decrease healthcare costs. Red Blood Cell (RBC) transfusion is common after cardiac..
Read MoreAbstract Autologous blood transfusion can be achieved through different techniques, including by the patient donating blood before surgery (pre-deposit), collecting blood from the patient immediately before the operation and replacing..
Read MoreAbstract Objectives Patients undergoing cardiac surgery often require , which are associated with increased morbidity and mortality. Patient blood management (PBM) strategies, including acute normovolemic (ANH), have been implemented to minimize allogeneic..
Read MoreAbstract Background The use of crystalloid priming for extracorporeal circuit in adult cardiac surgery causes inevitable haemodilution. The haemodilution can be reduced by using methods such as retrograde autologous priming..
Read MoreAbstract Study Objective: To investigate whether large volume acute normovolemic (L-ANH), compared with moderate acute normovolemic (M-ANH), can reduce perioperative allogeneic with intermediate-high risk of transfusion during cardiac surgery with (CPB). Design: Prospective . Setting:..
Read MoreAbstract Background The adverse effects of cardiopulmonary bypass during open cardiac surgery, including hemodilution, seem to be inevitable, especially for patients who generally have a relatively lower BMI with relatively..
Read MoreAbstract Objective: The study aimed to evaluate the effect of mild and moderate hemodilution during CPB on the neurocognitive dysfunction in patients undergoing coronary artery bypass grafting. Design: A randomized clinical study. ..
Read MoreAbstract Background: During the last decades many efforts have been made to reduce transfusion requirements and adverse clinical effects during cardiopulmonary bypass (CPB). The minimal extracorporeal circulation (MECC) system and the..
Read MoreAbstract Background: Although conventional cardiopulmonary bypass (cCPB) is still the most widely used method in open heart surgery, methods such as retrograde autologous priming (RAP) are increasingly popular in terms..
Read MoreAbstract Objective: Compare the use of blood products and intravenous fluid management in patients scheduled for coronary artery bypass surgery and randomized to minimal invasive extracorporeal circulation (MiECC) and conventional..
Read MoreAbstract The American Society for Testing and Materials (ASTM) F1841 standard for the assessment of hemolysis in blood pumps recommends using phosphate-buffered saline (PBS) for hemodilution to standardize hematocrit (HCT)...
Read MoreAbstract UNLABELLED:Hemodilution during cardiopulmonary bypass (CPB) is a primary risk factor for blood transfusion in cardiac surgical patients. Priming of the CPB circuit with the patients' own blood (retrograde autologous..
Read MoreAbstract The current practice of cardiopulmonary bypass (CPB) requires a preoperative priming of the circuit that is frequently performed with crystalloid solutions. Crystalloid priming avoids massive embolism but is unable..
Read MoreLecture and discussion on optimizing hemoglobin and why hemoglobin thresholds alone may not be best for assuring adequacy of perfusion during open heart surgery.
Read MoreThe learner will be able to discuss the pros and cons of blood transfusions and the morbidities associated with transfusion and the morbidities associated with excessive hemodilution.
Read MoreAbstract Objective has been associated with both and in studies based on (TEG). Severe hemodilution during (CPB) is a risk factor for morbidity in cardiac surgery. This study investigated the effects of different degrees..
Read MoreAbstract Background: Coronary artery bypass surgery is the most commonly performed cardiac operation and approximately 40-70% of patients require a blood transfusion despite improvements in cardiac surgical techniques. Some preventive..
Read MoreAbstract Background: We designed a non-invasive, observational, real-time study, using near-infrared spectroscopy (NIRS) to assess the in vivo effects of cardiopulmonary bypass (CPB) on patients’ skeletal muscle as well as..
Read MoreAbstract Systemic inflammatory response and are prominent factors associated with and result in increased morbidity and mortality in children. Miniaturized systems have evolved to decrease such effects and restrict use of blood..
Read MoreAbstract The desired use of the HPH Jr. is optimal due to the low priming volume; however, the lower rate of volume removal necessitates utilization of a larger hemofilter. Larger..
Read MoreRetrograde Autologous Priming in Cardiac Surgery: Results From a Systematic Review and Meta-analysis
Abstract Background: Retrograde autologous priming (RAP) before cardiopulmonary bypass (CPB) may minimize allogeneic red cell transfusion. We conducted a systematic review of the literature to examine the impact of RAP..
Read MoreAbstract Objective: Hemodilution is a concern in cardiopulmonary bypass (CPB). Using a smaller dual tubing rather than a single larger inner diameter (ID) tubing in the venous limb to decrease..
Read MoreAbstract Objectives: Minimal extracorporeal circulation techniques and systems (MiECC) may reduce the negative side effects of conventional extracorporeal circulation (ECC). However, it is still unclear as to what this is caused..
Read MoreAbstract Background Acute normovolemic hemodilution (ANH) is considered safe and effective in decreasing perioperative transfusion in paediatric populations undergoing high blood‐loss surgeries. We determined the association between ANH and the..
Read MoreAbstract Background A high hematocrit level in patients with erythrocytosis is linked with increased blood viscosity and increased risk of thromboembolism. Therefore, it is necessary to adequately lower the hematocrit..
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