Abstract Background It is hypothesized that combining HA380 with cardiopulmonary bypass (CPB) in acute type A aortic dissection (ATAAD) surgery could reduce the inflammatory response induced by CPB and subsequently..
Read MoreAbstract Objectives Severe perioperative bleeding occurs in over 30 % of patients on ticagrelor undergoing isolated coronary artery bypass grafting (i-CABG) before completing the recommended 3-day washout. Intraoperative ticagrelor removal with..
Read MoreAbstract Background/Objectives: Septic shock remains a significant clinical challenge with consistently high mortality rates. Recent investigations have focused on the efficacy of CytoSorb® (CytoSorbents Corporation, Monmouth Junction, NJ, USA), an extracorporeal..
Read MoreAbstract Background Cardiopulmonary bypass (CPB) triggers marked cytokine release often followed by a systemic inflammatory response syndrome, associated with adverse postoperative outcomes. This trial investigates the intraoperative use of haemoadsorption..
Read MoreAbstract OBJECTIVES Multi-organ failure is one of the leading causes of mortality after cardiac surgery for infective endocarditis (IE). Although the randomized evidence does not support the use of haemoadsorption..
Read MoreAbstract The usage of cardiopulmonary bypass (CPB) in cardiothoracic surgery contributes to the activation of the inflammatory response. In certain cases, the systemic inflammatory response may be immoderate, leading to..
Read MoreAbstract Background Rhabdomyolysis describes a syndrome characterized by muscle necrosis and the subsequent release of creatine kinase and myoglobin into the circulation. Myoglobin elimination with extracorporeal hemoadsorption has been shown..
Read MoreAbstract Introduction Prevention of acute kidney injury during cardiopulmonary bypass (CPB) is still a challenge and has been the object of numerous studies. The incidence of acute kidney injury in..
Read MoreAbstract Background Extracorporeal blood purification has been widely used in intensive care medicine, nephrology, toxicology, and other fields. During the last decade, with the emergence of new adsorptive blood purification..
Read MoreAbstract Background: Acute respiratory distress syndrome (ARDS) is often a consequence of a dysregulated immune response; therefore, immunomodulation by extracorporeal cytokine removal has been increasingly used as an adjuvant therapy, but..
Read MoreAbstract Blood purification by dialysis is a nephrology cornerstone. However, despite its success, dialysis has not systematically moved to the treatment of other conditions, such as liver failure, intoxication with..
Read MoreAbstract Background The management of hemostasis in patients medicated with apixaban (Eliquis) undergoing emergency cardiac surgery is exceedingly difficult. The body’s natural elimination pathways for apixaban prove ineffective in emergency..
Read MoreAbstract Objectives: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19..
Read MoreAbstract Venlafaxine is a serotonin and noradrenalin reuptake inhibitor prescribed as an antidepressant. Overdose clinically manifests with neurological, cardiovascular and gastrointestinal abnormalities based on, amongst others, serotonin syndrome and can..
Read MoreAbstract PRINCETON, N.J., March 07, 2023 (GLOBE NEWSWIRE) -- (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using blood purification, announces that..
Read MoreThis case reports on an a 67-year-old woman with CHILD-C liver cirrhosis, who was admitted to the tertiary intensive care unit (ICU) after intoxication with bromazepam. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/12/CoW_41_2022_E_web_compressed.pdf"]
Read MoreHemoadsorption in infective endocarditis and antithrombotic removal in the cardiosurgical setting: an update Prof. Dr. med. Daniel Wendt Update of the current literature Patient selection Cost effectiveness Outlook ..
Read MoreAbstract Background: Patients on direct oral anticoagulants are at high risk of perioperative bleeding complicaapitions. We analyzed the results of intraoperative hemoadsorption (HA) in patients undergoing cardiac surgery who were..
Read MoreAbstract Introduction: Immunomodulatory therapies have shown beneficial effects in patients with severe COVID-19. Patients with hypercytokinemia might benefit from the removal of inflammatory mediators via hemadsorption. Methods: Single-center prospective randomized trial at..
Read MoreAbstract Extracorporeal hemoadsorption with the CytoSorb adsorber is increasingly being used during the past years. The use in combination with extracorporeal membrane oxygenation (ECMO) is feasible, but frequency of its use and..
Read MoreAbstract Background: Antithrombotic drugs increase the risk of bleeding, especially in patients who need urgent surgery without an adequate wash-out period. This review aims to evaluate perioperative bleeding complications in..
Read MoreAbstract Background Postoperative sepsis is an important cause of morbidity and mortality in patients with infective endocarditis undergoing surgical therapy. Blood purification using hemoadsorption therapy shows promising results in the..
Read MoreAbstract Introduction: We performed an analysis of two blood purification systems to determine their performance for removing interleukins (ILs)-6 and 10, tumor necrosis factor (TNF)-α and monocyte chemoattractant protein (MCP)-1 from..
Read MoreAbstract Extracorporeal hemoadsorption with the CytoSorb adsorber is increasingly being used during the past years. The use in combination with extracorporeal membrane oxygenation (ECMO) is feasible, but frequency of its use and..
Read MoreA 64-year-old female was admitted to the Emergency Department after she was found somnolent by her daughter [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/05/CoW_21_2022_E_web_compressed.pdf"]
Read More- Hemoadsorption with CytoSorb as part of an individualized therapy in critically-ill patients Chair: Manu Malbrain, Leuven, Belgium and Yatin Mehta, Gurgaon, India - How to balance sepsis campaign guidelines..
Read MoreThis case reports on a 13-year-old boy, who was admitted to the hospital for coryzal symptoms (acute inflammation of the upper respiratory tract) and chest pain. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/03/CoW_09_2022_E_web_compressed.pdf"]
Read MoreThis case reports on a 61-year-old woman with confirmed COVID-19, who was admitted to a different hospital with a productive cough that she had had for a few days. [pdf-embedder..
Read MoreAbstract Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the..
Read MoreAbstract Hemodynamic instability due to dysregulated host response is a life-threatening condition requiring vasopressors and vital organ support. Hemoadsorption with Cytosorb has proven to be effective in reducing cytokines and..
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