Tags Archives: hemoadsorption

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Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection

Abstract Background It is hypothesized that combining HA380 with cardiopulmonary bypass (CPB) in acute type A aortic dissection (ATAAD) surgery could reduce the inflammatory response induced by CPB and subsequently..

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Early CABG with intraoperative hemoadsorption in patients on ticagrelor: Real world data from the international Safe and Timely Antithrombotic Removal…

Abstract Objectives Severe perioperative bleeding occurs in over 30 % of patients on ticagrelor undergoing isolated coronary artery bypass grafting (i-CABG) before completing the recommended 3-day washout. Intraoperative ticagrelor removal with..

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Hemoadsorption in the Management of Septic Shock: A Systematic Review and Meta-Analysis

Abstract Background/Objectives: Septic shock remains a significant clinical challenge with consistently high mortality rates. Recent investigations have focused on the efficacy of CytoSorb® (CytoSorbents Corporation, Monmouth Junction, NJ, USA), an extracorporeal..

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Removal of cytokines during cardiac surgery (RECCAS): a randomised controlled trial

Abstract Background Cardiopulmonary bypass (CPB) triggers marked cytokine release often followed by a systemic inflammatory response syndrome, associated with adverse postoperative outcomes. This trial investigates the intraoperative use of haemoadsorption..

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Effect of haemoadsorption during cardiac surgery for Staphylococcus aureus endocarditis: a REMOVE trial post hoc analysis Get access Arrow

Abstract OBJECTIVES Multi-organ failure is one of the leading causes of mortality after cardiac surgery for infective endocarditis (IE). Although the randomized evidence does not support the use of haemoadsorption..

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Impact of extracorporeal haemoadsorption during prolonged cardiopulmonary bypass on the incidence of acute kidney injury

Abstract The usage of cardiopulmonary bypass (CPB) in cardiothoracic surgery contributes to the activation of the inflammatory response. In certain cases, the systemic inflammatory response may be immoderate, leading to..

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Hemoadsorption therapy for myoglobin removal in rhabdomyolysis: consensus of the hemoadsorption in rhabdomyolysis task force

Abstract Background Rhabdomyolysis describes a syndrome characterized by muscle necrosis and the subsequent release of creatine kinase and myoglobin into the circulation. Myoglobin elimination with extracorporeal hemoadsorption has been shown..

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Hemadsorption to Contain Postoperative Cell-Free Hemoglobin and Haptoglobin Preservation for Extended Cardiopulmonary Bypass Time in Cardiac Surgery for Acute Kidney…

Abstract Introduction Prevention of acute kidney injury during cardiopulmonary bypass (CPB) is still a challenge and has been the object of numerous studies. The incidence of acute kidney injury in..

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The role of hemoadsorption in cardiac surgery – a systematic review

Abstract Background Extracorporeal blood purification has been widely used in intensive care medicine, nephrology, toxicology, and other fields. During the last decade, with the emergence of new adsorptive blood purification..

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Hemoadsorption as Adjuvant Therapy in Acute Respiratory Distress Syndrome (ARDS): A Systematic Review and Meta-Analysis

Abstract Background: Acute respiratory distress syndrome (ARDS) is often a consequence of a dysregulated immune response; therefore, immunomodulation by extracorporeal cytokine removal has been increasingly used as an adjuvant therapy, but..

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Hemoadsorption

Abstract Blood purification by dialysis is a nephrology cornerstone. However, despite its success, dialysis has not systematically moved to the treatment of other conditions, such as liver failure, intoxication with..

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Effective Apixaban removal using hemoadsorption during emergent open-heart surgery: a case report and narrative literature review

Abstract Background The management of hemostasis in patients medicated with apixaban (Eliquis) undergoing emergency cardiac surgery is exceedingly difficult. The body’s natural elimination pathways for apixaban prove ineffective in emergency..

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Extracorporeal hemoadsorption in critically ill COVID-19 patients on VV ECMO: the CytoSorb therapy in COVID-19 (CTC) registry

Abstract Objectives: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19..

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Successful use of extracorporeal life support and hemadsorption in the context of venlafaxine intoxication requiring cardiopulmonary resuscitation: a case report

Abstract Venlafaxine is a serotonin and noradrenalin reuptake inhibitor prescribed as an antidepressant. Overdose clinically manifests with neurological, cardiovascular and gastrointestinal abnormalities based on, amongst others, serotonin syndrome and can..

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New European “Guidelines for the Management of Severe Perioperative Bleeding” Consider Hemoadsorption for the First-Time

Abstract PRINCETON, N.J., March 07, 2023 (GLOBE NEWSWIRE) --  (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in the intensive care unit and cardiac surgery using blood purification, announces that..

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Hemadsorption: A New Therapeutic Option for Selected Cases of Bromazepam Intoxication

This case reports on an a 67-year-old woman with CHILD-C liver cirrhosis, who was admitted to the tertiary intensive care unit (ICU) after intoxication with bromazepam. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/12/CoW_41_2022_E_web_compressed.pdf"]  

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Hemoadsorption in cardiac surgery - New data and trends for successful use of CytoSorb - 2022

Hemoadsorption in infective endocarditis and antithrombotic removal in the cardiosurgical setting: an update Prof. Dr. med. Daniel Wendt Update of the current literature Patient selection Cost effectiveness Outlook    ..

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Removal of Apixaban during Emergency Cardiac Surgery Using Hemoadsorption with a Porous Polymer Bead Sorbent

Abstract Background: Patients on direct oral anticoagulants are at high risk of perioperative bleeding complicaapitions. We analyzed the results of intraoperative hemoadsorption (HA) in patients undergoing cardiac surgery who were..

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Effect of Hemadsorption Therapy in Critically Ill Patients with COVID-19 (CYTOCOV-19): A Prospective Randomized Controlled Pilot Trial

Abstract Introduction: Immunomodulatory therapies have shown beneficial effects in patients with severe COVID-19. Patients with hypercytokinemia might benefit from the removal of inflammatory mediators via hemadsorption. Methods: Single-center prospective randomized trial at..

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Survival of Patients Treated with Extracorporeal Hemoadsorption and Extracorporeal Membrane Oxygenation: Results from a Nation-Wide Registry

Abstract Extracorporeal hemoadsorption with the CytoSorb adsorber is increasingly being used during the past years. The use in combination with extracorporeal membrane oxygenation (ECMO) is feasible, but frequency of its use and..

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Management of perioperative bleeding risk in patients on antithrombotic medications undergoing cardiac surgery—a systematic review

Abstract Background: Antithrombotic drugs increase the risk of bleeding, especially in patients who need urgent surgery without an adequate wash-out period. This review aims to evaluate perioperative bleeding complications in..

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Intraoperative hemoadsorption in high-risk patients with infective endocarditis

Abstract Background Postoperative sepsis is an important cause of morbidity and mortality in patients with infective endocarditis undergoing surgical therapy. Blood purification using hemoadsorption therapy shows promising results in the..

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Comparison of the CytoSorb ® 300 mL and Jafron HA380 hemoadsorption devices: an in vitro study

Abstract Introduction: We performed an analysis of two blood purification systems to determine their performance for removing interleukins (ILs)-6 and 10, tumor necrosis factor (TNF)-α and monocyte chemoattractant protein (MCP)-1 from..

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Survival of Patients Treated with Extracorporeal Hemoadsorption and Extracorporeal Membrane Oxygenation: Results from a Nation-Wide Registry

Abstract Extracorporeal hemoadsorption with the CytoSorb adsorber is increasingly being used during the past years. The use in combination with extracorporeal membrane oxygenation (ECMO) is feasible, but frequency of its use and..

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Successful treatment of severe quetiapine intoxication with CytoSorb hemoadsorption

A 64-year-old female was admitted to the Emergency Department after she was found somnolent by her daughter [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/05/CoW_21_2022_E_web_compressed.pdf"]

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ISICEM 2022 CytoSorbents Symposium: Hemoadsorption with CytoSorb

- Hemoadsorption with CytoSorb as part of an individualized therapy in critically-ill patients Chair: Manu Malbrain, Leuven, Belgium and Yatin Mehta, Gurgaon, India - How to balance sepsis campaign guidelines..

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Single-pass albumin dialysis and hemoadsorption for bilirubin and bile acids removal for a child with hyperbilirubinemia after ventricular assist device…

This case reports on a 13-year-old boy, who was admitted to the hospital for coryzal symptoms (acute inflammation of the upper respiratory tract) and chest pain. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/03/CoW_09_2022_E_web_compressed.pdf"]

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Kinetics of Bilirubin and Ammonia Elimination during Hemadsorption Therapy in Secondary Sclerosing Cholangitis Following ECMO Therapy and Severe COVID-19

This case reports on a 61-year-old woman with confirmed COVID-19, who was admitted to a different hospital with a productive cough that she had had for a few days. [pdf-embedder..

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Use of Hemoadsorption in Patients With Severe Intoxication Requiring Extracorporeal Cardiopulmonary Support—A Case Series

Abstract Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the..

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The Potential Role of Extracorporeal Cytokine Removal in Hemodynamic Stabilization in Hyperinflammatory Shock

Abstract Hemodynamic instability due to dysregulated host response is a life-threatening condition requiring vasopressors and vital organ support. Hemoadsorption with Cytosorb has proven to be effective in reducing cytokines and..

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