Tags Archives: gas exchange

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A Validated CFD Model for Gas Exchange in Hollow Fiber Membrane Oxygenators: Incorporating the Bohr and Haldane Effects

Abstract Chronic respiratory diseases claim nearly four million lives annually, making them the third leading cause of death worldwide. Extracorporeal membrane oxygenation (ECMO) is often the last line of support..

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Optimizing Extracorporeal Membrane Oxygenation Gas Exchange: Key Insights for Clinical Management

Abstract This review examines the role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory distress syndrome (ARDS), emphasizing its contribution to lung-protective ventilation through optimizing oxygenation..

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Numerical Investigation of Gas Exchange Processes in Hollow-Fiber Membrane Bundles

Abstract The geometric configuration of fiber bundles plays a critical role in gas transfer for membrane oxygenators; however, experimentally studying its impact on gas transfer distribution is challenging. This study..

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Rethinking ARDS classification: oxygenation impairment fails to predict VILI risk

Abstract Purpose: The selection and intensity of respiratory support for ARDS are guided by PaO 2/FiO2 . However, ventilator-induced lung injury (VILI) is linked to respiratory mechanics and ventilator settings...

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Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation

Abstract Background The continuous exposure of blood to a non-biological surface during extracorporeal membrane oxygenation (ECMO) may lead to progressive thrombus formation in the oxygenator, hemolysis and consequently impaired gas..

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The effect of excessive gas to blood ratios in an ECMO oxygenator

Abstract Introduction Oxygenators for paediatric Extracorporeal Membrane Oxygenation (ECMO) are required to operate over a wide range of flow rates, in a patient group ranging from neonates through to fully..

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Physiology of Extracorporeal Gas Exchange

Abstract Circulating venous blood outside the body, through an artificial lung (membrane oxygenator), andreturning oxygenated blood to the patient is extracorporeal gas exchange. Oxygen and carbondioxide exchange in a membrane..

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In vitro evaluation of the performance of an oxygenator depending on the non-standard gas content of the inlet blood with…

Abstract Introduction The performance of an oxygenator, as found in literature, is evaluated according to protocols that define standard values of the gas content in the inlet blood. However, when..

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A new approach towards extracorporeal gas exchange and first in vitro results

Abstract Objectives Extracorporeal life support (ECLS) pertains to therapeutic and prophylactic techniques utilized in a wide range of medical applications, with severe pulmonary diseases being the most prominent cases. Over..

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How I manage differential gas exchange in peripheral venoarterial extracorporeal membrane oxygenation

Abstract Dual circulation is a common but underrecognized physiological occurrence associated with peripheral venoarterial extracorporeal membrane oxygenation (ECMO). Competitive flow will develop between blood ejected from the heart and blood..

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