Abstract Extracorporeal Life Support (ECLS), including venovenous (VV) extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) is a temporary support option for patients with severe respiratory failure. Current..
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Abstract Extracorporeal carbon dioxide removal (ECCO2R) is increasingly used in clinical practice as a means of facilitating protective mechanical ventilation and reducing the risk of ventilator-induced lung injury (VILI) in patients..
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Abstract Extracorporeal Carbon Dioxide Removal (ECCO2R) systems support patients with severe respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes, but these procedures are limited by the complexity and..
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Abstract The therapeutic target of extracorporeal carbon dioxide removal (ECCO2R) is the elimination of carbon dioxide (CO2) from the blood across a gas exchange membrane without influencing oxygenation to a clinically relevant..
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Abstract Our objective was to assess the relationship between the pre-/post-oxygenator gradient of the partial pressure of carbon dioxide (∆EC PCO2; dissolved form) and CO2 elimination under extracorporeal respiratory support. All patients..
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Abstract Severe acute hypercapnia is independently associated with increased adverse effects and intensive care unit mortality in mechanically ventilated patients. During the severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic,..
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High- versus Low-Flow Extracorporeal Respiratory Support in Experimental Hypoxemic Acute Lung Injury
Abstract Rationale: In the EOLIA (ECMO to Rescue Lung Injury in Severe ARDS) trial, oxygenation was similar between intervention and conventional groups, whereas V˙V˙e was reduced in the intervention group. Comparable reductions in..
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Abstract Extracorporeal CO2 removal (ECCO2R) was introduced in 1977 to control arterial CO2 tension and reduce ven- tilation, thus allowing lung rest in patients with acute respiratory failure (ARF). Its..
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Abstract The aim of this retrospective multicenter observational study is to test the feasibility and safety of a combined extracorporeal CO2 removal (ECCO2R) plus renal replacement therapy (RRT) system to use..
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Abstract Extracorporeal carbon dioxide removal (ECCO2R) has gained widespread use as a supposedly less invasive alternative for hypercapnic respiratory failure besides venovenous extracorporeal membrane oxygenation (VV ECMO). Despite technological advances,..
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Abstract Low flow extracorporeal carbon dioxide removal (ECCO2R) is a promising approach to correct hypercapnic lung failure, facilitate lung protective ventilation in acute respiratory distress syndrome and to possibly prevent..
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Abstract Extracorporeal life support (ECLS) for severe respiratory failure has seen an exponential growth in recent years. Extracorporeal membrane oxygenation (ECMO) and extracorporeal CO2 removal (ECCO2R) represent two modalities that can..
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Abstract Extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R) provide respiratory support aimed at gaining time to allow patient’s recovery from hypoxemic and/or hypercapnic respiratory failure, respectively. However, in..
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Abstract We retrospectively reviewed the medical records of 11 patients supported with a veno-venous low-flow extracorporeal carbon dioxide (CO2) removal (ECCO2R) device featuring a large gas exchange surface membrane lung..
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Abstract Extracorporeal CO2 removal is a highly promising support therapy for patients with hypercapnic respiratory failure but whose clinical implementation and patient benefit is hampered by high cost and highly specialized..
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