Tags Archives: ex vivo

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Ex Vivo Lung Perfusion (EVLP)

Ex Vivo Lung Perfusion (EVLP) has become a key strategy to assess, recondition, and safely transplant lungs from DCD (Donation after Circulatory Death) donors, particularly because of warm ischemia exposure...

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Report of the Portable Ex Vivo Organ Perfusion Workforce Survey: Staffing Models and Clinical Trends

Abstract Historically, organs recovered for transplant have been transported using static cold preservation. However, newer portable ex vivo organ perfusion (PEVOP) strategies allow warm organ perfusion during transport. Although PEVOP is a..

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Preparing lung transplant with Ex Vivo Lung Perfusion Device

Preparing the Child lung for transplant into the Adult patient with usage of EVLPD or Ex Vivo Lung Perfusion Device a practical application which every Perfusionist should be familiar with...

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Lung procurement with ex vivo lung perfusion

A complete advance series of lung procurement and usage of ex vivo lung perfusion technologies or device either in the presence of pulmonary thromboembolism.   Dr.Sam Zeraatian Nejad Davani, CEO..

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Hypothermic oxygenated perfusion (HOPE) safely and effectively extends acceptable donor heart preservation times: Results of the Australian and New Zealand…

Abstract Background Cold static storage preservation of donor hearts for periods longer than 4 hours increases the risk of primary graft dysfunction (PGD). The aim of the study was to determine..

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Polymerized Human Hemoglobin–Based Oxygen Carrier Preserves Lung Allograft Function During Normothermic Ex Vivo Lung Perfusion

Abstract Normothermic ex vivo lung perfusion (EVLP) can resuscitate marginal lung allografts to increase organs available for transplantation. During normothermic perfusion, cellular metabolism is more active compared with subnormothermic perfusion, creating a..

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Successful heart transplant after 12 h preservation aboard a commercial flight

Abstract For the first time, a heart transplant has been successfully performed after transport of a donor heart across the Atlantic Ocean, marking a substantial advancement in the realm of..

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Ex Vivo Optimization of Donor Lungs with Inhaled Sevoflurane during Normothermic Ex Vivo Lung Perfusion (VITALISE): A Pilot and Feasibility…

Abstract Volatile anesthetics have been shown in different studies to reduce ischemia reperfusion injury (IRI). Ex vivo lung perfusion (EVLP) facilitates graft evaluation, extends preservation time and potentially enables injury..

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CytoSorb with Ex Vivo Organ Perfusion: Transforming the Future of Solid Organ Transplantation

Abstract PRINCETON, N.J., Sept. 11, 2023 (GLOBE NEWSWIRE) --   (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in intensive care and cardiac surgery using blood purification via its..

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Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History

Abstract Heart transplantation is considered the gold standard for the treatment of advanced end-stage heart failure. However, standard donors after brain death are decreasing, whereas patients on the heart transplant waitlist are..

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A report of the first pediatric heart transplant following donation after circulatory death in the United States using ex-vivo perfusion

Abstract Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients. We..

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Remote ex vivo lung perfusion at a centralized evaluation facility

Abstract Background: In the US, only 23% of lungs offered for transplantation are transplanted. Ex vivo lung perfusion (EVLP) allows for evaluation of additional donor lungs; its adoption has been limited..

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Ex Vivo Lung Perfusion: A Review of Current and Future Application in Lung Transplantation

Abstract The number of waitlisted lung transplant candidates exceeds the availability of donor organs. Barriers to utilization of donor lungs include suboptimal lung allograft function, long ischemic times due to..

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Sequestration of Midazolam, Fentanyl, and Morphine by an Ex Vivo Cardiopulmonary Bypass Circuit

Abstract Cardiopulmonary bypass (CPB) circuits can significantly sequester intravenous anesthetics. Adsorption of medications by our institution’s standard circuit (Terumo CAPIOX FX05 oxygenator; noncoated polyvinylchloride tubing) has not been described. We..

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Sequestration of Midazolam, Fentanyl, and Morphine by an Ex Vivo Cardiopulmonary Bypass Circuit

Abstract Cardiopulmonary bypass (CPB) circuits can significantly sequester intravenous anesthetics. Adsorption of medications by our institution’s standard circuit (Terumo CAPIOX FX05 oxygenator; noncoated polyvinylchloride tubing) has not been described. We..

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Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients

Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..

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Sequestration of Dexmedetomidine in Ex Vivo Cardiopulmonary Bypass Circuits

Abstract Dexmedetomidine (DEX) is a sedative used in combination with other drugs in neonates and infants undergoing cardiac surgery using cardiopulmonary bypass (CPB). This study aimed to evaluate the disposition..

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