Tags Archives: ecmo

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Venting the Left Ventricle from the Atrium: A Case Series of transeptal LA Vent VA-ECMO

Abstract Introduction: In cardiogenic shock, peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide hemodynamic support, however this results in adverse left ventricular afterload. Left ventricle (LV) venting (unloading) has favorable effects..

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Mortality on extracorporeal membrane oxygenation: Evaluation of independent risk factors and causes of death during venoarterial and venovenous support

Abstract Introduction Most patients on extracorporeal membrane oxygenation (ECMO) decease during therapy on the system. However, the actual causes of death have not been studied sufficiently. This study analyses the..

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De senectute and the art of medicine: how old is too old for ECMO in cardiogenic shock?

Abstract Complexity and a certain level of uncertainty are inherent to the clinical scenarios faced by the treating teams, often inundated with exhaustive details. Disease arises from a multitude of..

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Peripheral Veno-Arterial-Extracorporeal Membrane Oxygenation for Refractory Septic Shock in Children: A Multicenter Review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is utilized as a rescue therapy in the management of pediatric patients with refractory septic shock. Multiple studies support the use of a central..

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Early Changes in Arterial Partial Pressure of Carbon Dioxide and Blood Pressure After Starting Extracorporeal Membrane Oxygenation in Children: Extracorporeal…

Abstract Objective:  Neurologic complications in pediatric patients supported by extracorporeal membrane oxygenation (ECMO) are common and lead to morbidity and mortality; however, few modifiable factors are known. Design:  Retrospective study..

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Outcomes in Obese Are Comparable to Non-Obese Patients: A Propensity Matched Cohort Study

Abstract Introduction: Obesity, defined as a body mass index ≥ 40 kg/m2, was considered a relative contraindication to cannulation for extra-corporeal membrane oxygenation (ECMO) during the coronavirus pandemic. While body habitus can..

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A safe and effective method for percutaneous, awake, bedside decannulation of peripheral VA ECMO using vascular closure devices: a case…

Abstract Decannulation of patients on peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) typically involves femoral arterial cutdown and surgical arteriotomy closure in an operating room under general anesthesia. However, this..

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How I manage differential gas exchange in peripheral venoarterial extracorporeal membrane oxygenation

Abstract Dual circulation is a common but underrecognized physiological occurrence associated with peripheral venoarterial extracorporeal membrane oxygenation (ECMO). Competitive flow will develop between blood ejected from the heart and blood..

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Radiation Exposure in Extracorporeal Life Support

Abstract Extracorporeal membrane oxygenation (ECMO) exposes patients to multiple radiologic studies. We hypothesized ECMO patients endure radiation exposure in excess of the International Commission of Radiological Protection (ICRP) recommendations of..

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Prevalence of FXII-Deficiency and Its Relevance to Monitoring Anticoagulation in Adults Receiving Extracorporeal Membrane Oxygenation

Abstract During extracorporeal membrane oxygenation (ECMO) blood is exposed to artificial surfaces, resulting in contact activation of the intrinsic coagulation pathway initiated by coagulation factor XII (FXII). Little is known..

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Anticoagulation strategies in COVID-19 infected patients receiving ECMO support

Abstract Background: Hospitalized COVID-19 patients with hypoxemic respiratory failure may deteriorate despite invasive mechanical ventilation and thus require extracorporeal membrane oxygenation (ECMO) support. Unfractionated heparin (UFH) is the antithrombotic of..

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Early Left Ventricular Unloading or Conventional Approach After Venoarterial Extracorporeal Membrane Oxygenation: The EARLY-UNLOAD Randomized Clinical Trial

Abstract BACKGROUND: Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) is beneficial for the treatment of profound cardiogenic shock, peripheral VA-ECMO cannulation can increase left ventricular afterload, thus compromising myocardial recovery. We..

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The role of ECMO support in airway procedures

Abstract The role of ECMO support in airway procedures

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Outcomes of Extracorporeal Life Support Utilization for Pediatric Patients With COVID-19 Infections

Abstract Outcomes of pediatric patients who received extracorporeal life support (ECLS) for COVID-19 remain poorly described. The aim of this multi-institutional retrospective observational study was to evaluate these outcomes and..

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ECMO for Premature Neonates- Are we there yet?

Abstract Despite ECMO being a well-accepted and established life-saving support for newborns, prematurity (<34 weeks of gestation) and low birth weight <2.0 kg are still considered relative contraindications due to..

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Lower Oxygen Tension and Intracranial Hemorrhage in Veno-venous Extracorporeal Membrane Oxygenation

Abstract Introduction and Methods We examined the relationship between 24-h pre- and post-cannulation arterial oxygen tension (PaO2) and arterial carbon dioxide tension (PaCO2) and subsequent acute brain injury (ABI) in..

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Challenges of Nutrition Support in Pediatric Patients Requiring Extracorporeal Membrane Oxygenation

Abstract Nutrition support in critically ill infants and children remains an integral part of providing optimal care for these patients. The pediatric patient requiring extracorporeal membrane oxygenation therapy faces specific..

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Extracorporeal Membrane Oxygenation Physiological Factors Influence Pulse Oximetry and Arterial Oxygen Saturation Discrepancies

Abstract Background  strategy, vasopressors, and hemolysis are important physiological factors that influence  in  (ECMO). We hypothesized these factors influence the discrepancy between  measured by  (Spo2) and  (Sao2)  on ECMO. Methods We retrospectively analyzed adults (aged ≥18..

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Multicenter Assessment of a Novel ECMO Cannulation Simulator Using a Standardized Procedural Checklist

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA ECMO) is an emergency procedure performed across various specialties. These conditions present barriers to education and assessment of competency. Checklists and simulation may be..

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Factor XII promotes the thromboinflammatory response in a rat model of venoarterial extracorporeal membrane oxygenation

Abstract Background  (FXII) is a multifunctional  capable of activating thrombotic and inflammatory pathways. FXII has been linked to thrombosis in  (ECMO), but the role of FXII in ECMO-induced inflammatory complications has not..

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Commercial and novel anticoagulant ECMO coatings: a review

Abstract Extracorporeal membrane oxygenation (ECMO) is an invasive and last-resort treatment for circulatory and respiratory failure. Prolonged ECMO support can disrupt the coagulation and anticoagulation systems in a patient, leading..

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The effects of nitric oxide on coagulation and inflammation in ex vivo models of extracorporeal membrane oxygenation and cardiopulmonary bypass

Abstract Background Extracorporeal life support (ECLS) has extensive applications in managing patients with acute cardiac and pulmonary failure. Two primary modalities of ECLS, cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation..

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Bleeding patients on extracorporeal membrane oxygenation have reduced platelet aggregation and plasma fibrinogen: a longitudinal observational study

Abstract This study investigated changes in coagulation and associations with occurrence of bleeding and thrombosis during extracorporeal membrane oxygenation (ECMO) therapy. The study included 100 adult ECMO-patients. Standard coagulation parameters,..

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Phosphorylcholine/Heparin Composite Coatings on Artificial Lung Membrane for Enhanced Hemo-compatibility

Abstract As the key component of extracorporeal membrane oxygenation (ECMO), artificial lung membranes have low gas permeability and plasma leakage problems, and the contact between membrane materials and blood can..

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Comparison of Serial and Parallel Connections of Membrane Lungs against Refractory Hypoxemia in a Mock Circuit

Abstract Extracorporeal membrane oxygenation (ECMO) is an important rescue therapy method for the treatment of severe hypoxic lung injury. In some cases, oxygen saturation and oxygen partial pressure in the..

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Standardized approach for extubation during extracorporeal membrane oxygenation in severe acute respiratory distress syndrome: a prospective observational study

Abstract Background Extubation during extracorporeal oxygenation (ECMO) in severe acute respiratory distress syndrome(ARDS) has not been well studied. Despite the potential benefits of this strategy, weaning from ECMO before libera‑tion..

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Groundbreaking NIH Study Reveals: ECMO More Effective for Obese Patients than Previously Thought!

Abstract The escalating concern of obesity in the United States isn’t merely a statistic; it’s a palpable crisis. As of 2017-2018, the CDC noted that . The ramifications of this startling..

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Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

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Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

Abstract Background Venoarterial  (VA-ECMO) is increasingly used  with  despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..

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Antithrombin III supplementation during neonatal and pediatric extracorporeal membrane oxygenation

Abstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced..

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