Abstract Background Organ dysfunction after cardiac surgery may be reduced by dexmedetomidine. We evaluated whether perioperative dexmedetomidine reduces complications after cardiac surgery with cardiopulmonary bypass. Methods In this randomised, double-blind,..
Read MoreAbstract Cardiac procedures carry a higher perioperative risk than other operations for major adverse cardiovascular events and kidney injury, especially since patients with multiple comorbidities have been accepted as candidates..
Read MoreAbstract Purpose: Dexmedetomidine, an alpha-2 adrenergic agonist, has shown potential benefits in various surgical settings, but its impact on microcirculation and renal function in cardiac surgery patients remains unclear. Patients and..
Read MoreAbstract Objective This study aims to investigate pulmonary protective and antiinflammatory effects of dexmedetomidine (DEX) in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) by meta-analysis. Methods Six databases were..
Read MoreAbstract Objective To assess the effects of dexmedetomidine (DEX) on cerebrovascular autoregulation in children with congenital heart disease (CHD) using transcranial color-coded duplex sonography (TCCD). Design Randomized controlled trial. Setting..
Read MoreAbstract Background In cardiac surgery, the extent of systemic inflammatory response is closely Mobile associated with patient’s outcome. A systemic inflammatory response syndrome (SIRS) may develop after operations using cardiopulmonary..
Read MoreAbstract Dexmedetomidine (DEX) is a sedative used in combination with other drugs in neonates and infants undergoing cardiac surgery using cardiopulmonary bypass (CPB). This study aimed to evaluate the disposition..
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