Abstract Cytokine hemoadsorption therapy has been proposed to reduce inflammation in patients with hyperinflammation. However, the clinical benefit of cytokine hemoadsorption therapy during venovenous extracorporeal membrane oxygenation (VV ECMO) is..
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Abstract Background: Cardiac surgery can lead to dysregulation with a pro-inflammatory state, resulting in adverse outcomes. Hemadsorption using the AN69 membrane (Oxiris membrane) has the properties to chelate inflammatory cytokines...
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Abstract Objectives: To investigate the impact of a cytokine haemoadsorption (HA) device (CytoSorb®) on inflammatory markers and patients' outcome during aortic root surgery. Methods: Prospective, observational study including all-comers with quasi-randomization by..
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Abstract Multiple organ failure following a septic event derives from immune dysregulation. Many of the mediators of this process are humoral factors (cytokines), which could theoretically be cleared by direct..
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Abstract Objectives Patients with endocarditis requiring urgent valvular surgery with cardiopulmonary bypass are at a high risk of developing systemic inflammatory response syndrome and septic shock, necessitating intensive use of..
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Abstract Background: Cardiac surgery often represents the only treatment option in patients with infective endocarditis (IE). However, IE surgery may lead to a sudden release of inflammatory mediators, which is..
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A 35-year-old pregnant woman (gestational age 32 weeks) admitted to hospital due to COVID-19 pneumonia and severe respiratory failure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/12/CoW_50_2021_E_web_compressed.pdf"]
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Despite the critical role of cytokines in the modulation of the immune response, cytokine hyperactivity has been implicated in the pathogenesis of severe organ failure secondary to sepsis, cardiac surgery,..
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