Abstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..
Read MoreAbstract Background Prophylactic corticosteroids have been widely used to mitigate the inflammatory response induced by cardiopulmonary bypass (CPB). However, the impact of this treatment on clinically important outcomes in infants..
Read MoreAbstract Background Cardiac surgery triggers a strong inflammatory reaction, which carries significant clinical consequences. Corticosteroids have been suggested as a potential perioperative strategy to reduce inflammation and help prevent postoperative..
Read MoreAbstract Objective Perioperative corticosteroids have been used for cardiac surgery for decades, but the underlying evidence is conflicting. We aimed to investigate the efficacy and safety of perioperative prophylactic corticosteroids in heart..
Read MoreAbstract An updated systematic review with meta-analysis comparing perioperative prophylactic administration of corticosteroids with placebo in cardiac surgeries using was conducted. The Cochrane Central Register of Controlled Trials and MEDLINE (via PubMed)..
Read MoreAbstract The advantages and disadvantages of using corticosteroids in children undergoing cardiac surgery is still contentious. To examine how perioperative corticosteroids affect postoperative mortality and clinical outcomes in pediatric cardiac..
Read MoreAbstract Objective Corticosteroids can attenuate the inflammatory response to cardiopulmonary bypass, but their benefits on clinical outcomes are unclear. We conducted a meta-analysis to evaluate whether corticosteroid therapy affects outcomes..
Read MoreAbstract Background Corticosteroids suppress the inflammatory response to in children undergoing cardiac surgery. What is less clear is the impact of corticosteroids on the postoperative course. Methods A systematic review and..
Read MoreImpact of Corticosteroids on Cardiopulmonary Bypass Induced Inflammation in Children:A Meta-Analysis
Abstract Background Corticosteroids (CS) suppress the inflammatory response to cardiopulmonary bypass in children undergoing cardiac surgery. What is less clear is the impact of CS on the postoperative course. Methods..
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