Tags Archives: cardiopulmonary bypass (CPB)

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Clinical evaluation of SafeCEC® one-way valve in hemolysis during CPB: Pilot study

Abstract Introduction: In cardiopulmonary bypass (CPB), blood circulation is temporarily maintained by an artificial blood-pumping device during cardiac surgery. Worldwide, approximately half of the CPB procedures utilize either centrifugal or..

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Time-dose response of oxygen delivery during cardiopulmonary bypass in mitral valve surgery: does surgical approach matter?

Abstract Introduction Increased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs...

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Transcutaneous Monitoring of Carbon Dioxide to Optimize Ventilator Weaning in At-Risk Adults After Cardiopulmonary Bypass

Abstract Background  Cardiopulmonary bypass use during surgery disrupts microcirculation, which can contribute to lung injury, particularly in patients with pulmonary comorbidities. Continuous transcutaneous carbon dioxide (CO2) monitoring assists clinicians to..

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The predictive power of hemodynamic data on postoperative neurocognitive impairment: a logistic regression and random forest approach

Abstract This study assesses hemodynamic data and parameter combinations in predicting neurocognitive impairment post-cardiopulmonary bypass graft (CABG) using logistic regression and random forest algorithms. 28 patients underwent the Montreal Cognitive..

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Sickle Cell Disease and Cardiopulmonary Bypass: A Multidisciplinary Approach to High-Risk Cardiac Surgery

1. Introduction Sickle Cell Disease (SCD) is a chronic, inherited blood disorder resulting from a single point mutation in the β-globin gene. This mutation leads to the production of hemoglobin..

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Minimizing Cardiopulmonary Bypass Time: Are We Saving Lives or Just Minutes?

In modern cardiac surgery, cardiopulmonary bypass (CPB) plays a life-saving role. It allows the heart to be stopped safely while the body is perfused with oxygenated blood. However, it’s a..

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Global trend of review articles focused on cardiopulmonary bypass: Perspectives from bibliometrics

Abstract BACKGROUND Cardiopulmonary bypass (CPB) is a life-support technology widely used in surgery. Review articles reflect research advances in a certain topic or field within a certain period of time...

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A Temperature-Adjusted Algorithm for Predicting Critical Indexed Oxygen Delivery (DO₂i) During Cardiopulmonary Bypass

Abstract Introduction: Indexed oxygen delivery (DO₂i) is a critical parameter in cardiopulmonary bypass (CPB) management. Traditional goal-directed perfusion (GDP) protocols use fixed DO₂i thresholds, typically derived from normothermic conditions. However,..

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Prophylactic corticosteroids in neonatal cardiac surgeries using cardiopulmonary bypass: a systematic review and meta-analysis

Abstract Purpose Neonates undergoing cardiopulmonary bypass (CPB) are at a high risk of a systemic inflammatory response leading to cardiac, respiratory, and renal dysfunction due to their small body size..

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Does the venous cannulation method affect gaseous embolic load to the patient during extracorporeal circulation?

Abstract Introduction Cardiopulmonary bypass (CPB) is essential for cardiac surgery but poses risks, including gaseous micro emboli (GME). While the incidence of stroke—a common clinical consequence of embolism—ranges from 1-5%..

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A novel blood volume monitoring approach in a venous reservoir using a laser displacement sensor for blood surface distance measurement

Abstract A venous reservoir (VR) is crucial for safe blood volume regulation during cardiopulmonary bypass (CPB) procedures. Currently, blood volume measurement in VRs relies heavily on visual inspection, which limits..

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Alteration in Indole Metabolites After Cardiopulmonary Bypass Surgery in Neonates and Infants

Abstract IMPORTANCE:  Cardiopulmonary bypass (CPB) surgery is associated with changes in the intestinal microbiome. Metabolism of tryptophan into the indole pathway is entirely facilitated by the intestinal microbiome, and indole..

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Impact of gender differences on optimal oxygen delivery thresholds to prevent acute kidney injury in cardiac surgeries with cardiopulmonary bypass

Abstract Background The nadir oxygen delivery index (DO2i) during cardiopulmonary bypass (CPB) is reportedly associated with acute kidney injury (AKI) in patients undergoing cardiac surgery. However, there are few reports..

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Frontoparietal and temporal brain alterations post-cardiopulmonary bypass

Abstract Patients undergoing cardiopulmonary bypass (CPB) often experience neurological complications, but the neurobiological mechanisms remain unclear. This study combined resting-state fMRI, structural MRI, and cognitive testing to examine brain changes..

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Minimal invasive extracorporeal circulation versus conventional cardiopulmonary bypass in cardiac surgery: a contemporary systematic review and meta-analysis

Abstract OBJECTIVES The question whether minimally invasive extracorporeal circulation (MiECC) represents the optimal perfusion strategy in cardiac surgery remains unanswered. We sought to systematically review the entire literature and thoroughly..

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Effect of cardiopulmonary bypass on late-onset hyperlactatemia after pediatric cardiac surgery

Abstract Background: This study aimed to investigate the effect of operative and postoperative parameters on late-onset hyperlactatemia (LOHL) after cardiac surgery in the pediatric patient population.Methods: One hundred fifty-nine ventricular septal defect..

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Outcomes after lung transplantation performed using elective cardiopulmonary bypass: A single-center experience

Abstract Background There remains significant variability in the use of intraoperative mechanical circulatory support in lung transplantation. This report details our outcomes using elective cardiopulmonary bypass (CPB) in lung transplantation...

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Persistent Renal Hypoxia and Histologic Changes at 4 Weeks after Cardiopulmonary Bypass in Sheep

Abstract Background:  The sustained renal effects of exposure to cardiopulmonary bypass are unknown. This study aimed to test whether cardiopulmonary bypass (CPB) is associated with sustained renal tissue hypoxia and..

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Intraoperative Hemolysis Monitoring by Real-time Point-of-care in Patients Undergoing Cardiopulmonary Bypass in Cardiac Surgery: A Single-centre Prospective Observational Study

Abstract Objective Hemolysis is a complication in surgical procedures requiring cardiopulmonary bypass (CPB). The primary aim of this study was to evaluate the effectiveness of the point-of-care device Hemcheck Helge..

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Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

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Principles and Functions of Cardiopulmonary Bypass (CPB).

Cardiopulmonary Bypass (CPB) is one of the most critical advancements in cardiac surgery. It allows the surgical team to operate on a non-beating heart by temporarily taking over the functions..

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Micronanoplastic exposure due to cardiopulmonary bypass in children: A prospective observational study

Abstract Cardiopulmonary bypass (CPB) is widely used in cardiac operations. However, it remains unclear whether a CPB circuit, which is mainly made of plastics, can release micronanoplastics (MNPs) into the..

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Development and validation of a checklist for cardiopulmonary bypass

Abstract Introduction: Risk prevention protocols related to patient care have been developed to reduce the incidence of adverse events in health care services. Cardiopulmonary bypass (CPB) can trigger several complications,..

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Impact of behavior change theory-based nursing interventions on cardiac function recovery and quality of life among cardiac surgery patients with…

Abstract Background This study investigates the impact of nursing interventions, guided by behavior change theory, on the recovery of cardiac function and quality of life in patients undergoing cardiac surgery..

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Managing Anticoagulation in Cardiopulmonary Bypass: Best Practices

Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, enabling complex procedures by temporarily taking over the heart and lung functions. However, one of the most critical aspects of..

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Advances in understanding the effects of cardiopulmonary bypass on gut microbiota during cardiac surgery

Abstract Cardiopulmonary bypass (CPB) is an indispensable technique in cardiac surgery; however, its impact on gut microbiota and metabolites remains insufficiently studied. CPB may disrupt the intestinal mucosal barrier, altering..

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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach

Abstract Objective This study sought to evaluate the value of a CO2 field-flooding device in cardiopulmonary bypass (CPB) surgical procedures for congenital heart disease (CHD) performed via a right-side small incision..

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Prebypass Critical Closing Pressure Predicts Acute Kidney Injury After Cardiopulmonary Bypass

Abstract Objectives Optimal blood pressure goals during cardiopulmonary bypass (CPB) remain uncertain and new metrics to individualize perfusion targets are needed. Critical closing pressure (Pcrit) is a fundamental property of..

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Development of and recovery from acute kidney injury after cardiac surgery: Randomized phase 2 trial of the hepatocyte growth factor…

Abstract Objectives To investigate the safety and efficacy of ANG-3777, a hepatocyte growth factor mimetic, in mitigating the risk of acute kidney injury (AKI) in patients undergoing cardiac surgery with..

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Innovative balloon-inflatable venous cannula for enhanced cardiopulmonary bypass in minimally invasive cardiac surgery

Abstract OBJECTIVES Minimally invasive cardiac surgery (MICS) struggles with effective caval isolation and cannulation for cardiopulmonary bypass (CPB). We aimed to develop a novel MICS venous cannula, eliminating external manipulations...

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