Tags Archives: cardiopulmonary bypass (CPB)

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A prospective, observational study of cerebrovascular autoregulation and its association with delirium following cardiac surgery

Summary This aim of this prospective observational cohort study was to evaluate any association between postoperatively impaired cerebrovascular autoregulation and the onset of delirium following cardiac surgery. Previous studies have..

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Red Blood Cell Disorders: Perioperative Considerations for Patients Undergoing Cardiac Surgery

Abstract Disorders affecting red blood cells (RBCs) are uncommon yet have many important physiologic considerations for patients undergoing cardiac surgery. RBC disorders can be categorized by those that are congenital..

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The effect of air exposure on leucocyte and cytokine activation in an in-vitro model of cardiotomy suction

Abstract Introduction: Cardiopulmonary bypass (CPB) is known to cause a systemic inflammatory and immune response. Objective: An in-vitro model of cardiotomy suction was designed to quantify the effects of incrementally increased air-blood..

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The Effect of Modified Ultrafiltration on Serum Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery

Abstract Objective The aim of this study was to investigate whether the use of  at the end of  for cardiac surgical procedures significantly changes  serum concentrations. Design Prospective study. Setting Single tertiary cardiac..

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Pediatric extracorporeal membrane oxygenation (ECMO): a guide for radiologists

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment for pediatric patients with respiratory and/or cardiac failure. The ECMO circuit oxygenates and sometimes pumps the blood, effectively replacing lung and/or..

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Perioperative Characteristics of the Accuracy of Subcutaneous Continuous Glucose Monitoring: Pilot Study in Neurosurgery and Cardiac Surgery

Abstract Background: The aim of this study was to elucidate the characteristics of accuracy of subcutaneous continuous glucose monitoring (SCGM) in the perioperative period for neurosurgical and cardiac surgery patients. Methods: Forty-five..

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Feasibility of autologous intraoperative blood collection and retransfusion in small children with complex congenital heart defects undergoing cardiopulmonary bypass

Abstract Introduction Allogeneic blood product transfusion is common in pediatric patients undergoing cardiopulmonary bypass although it is associated with an increased risk for adverse events. Furthermore, numerous donor exposures may..

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Cardiac Surgery–Associated Kidney Injury in Children and Renal Oximetry

Abstract Objectives:  Cardiac surgery–associated acute kidney injury is common in children and associates with negative outcomes. Novel interventions to reduce cardiac surgery–associated acute kidney injury require knowledge of its pathophysiology...

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Heparin–protamine balance after neonatal cardiopulmonary bypass surgery

Abstract Essentials   Heparin‐protamine balance (HPB) modulates bleeding after neonatal cardiopulmonary bypass (CPB). HPB was examined in 44 neonates undergoing CPB. Post‐operative bleeding occurred in 36% and heparin rebound in..

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Correlation among decreased regional cerebral oxygen saturation, blood levels of brain injury biomarkers, and cognitive disorder

Abstract Objective This study was performed to investigate the correlation among decreased regional cerebral oxygen saturation (rSO2), blood levels of brain injury biomarkers, and postoperative cognitive disorder (POCD) after cardiac..

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Improving hemolysis levels associated with cardiotomy suction

Abstract Background: The major source of hemolysis during cardiopulmonary bypass (CPB) remains the cardiotomy suction.1 Previous research has shown that the combination of negative pressures and the massive air-blood interface exponentially..

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Cardiopulmonary Bypass in Non-Cardiac Surgery

Background  (CPB) and  membrane oxygenation (ECMO) are used to facilitate  in standard cardiac surgery and emergency intervention, but CPB and ECMO are not used routinely in  involving the  and major vessels. The primary aim..

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A Table Mounted Cardiopulmonary Bypass System for Pediatric Cardiac Surgery

Abstract Systemic inflammatory response and  are prominent factors associated with  and result in increased morbidity and mortality in children. Miniaturized systems have evolved to decrease such effects and restrict use of blood..

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Comparison of Ringer’s Lactate and Plasmalyte-A as Cardiopulmonary Bypass Prime for Bypass Associated Acidosis in Valve Replacement Surgeries

Abstract Introduction A wide range of acid base fluctuations are seen during Cardiopulmonary bypass (CPB) and the development of metabolic acidosis is well recognized. We conducted a study tocompare the..

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Low Tidal Volume Mechanical Ventilation Against No Ventilation During Cardiopulmonary Bypass in Heart Surgery (MECANO): A Randomized Controlled Trial

Abstract Background Postoperative pulmonary complications are common after cardiac surgery and have been related to lung collapse during cardiopulmonary bypass (CPB). No consensus exists regarding the effects of maintaining mechanical..

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Microvascular Alterations During Cardiac Surgery Using a Heparin or Phosphorylcholine-Coated Circuit

Abstract Objective Heparin biocompatible coating frequently is used to reduce inflammation and blood coagulation during cardiopulmonary bypass (CPB) in cardiac surgery. Whether heparin coating is protective or damaging to the..

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Oxygen delivery, oxygen consumption and decreased kidney function after cardiopulmonary bypass

Abstract Introduction Low oxygen delivery during cardiopulmonary bypass is related to a range of adverse outcomes. Previous research specified certain critical oxygen delivery levels associated with acute kidney injury. However,..

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Impact of MELD score and cardiopulmonary bypass duration on post-operative hypoxic hepatitis in patients with liver cirrhosis undergoing open heart…

Abstract Background The outcome of open-heart surgery for patients with liver cirrhosis (LC) varies widely, indicating multifactorial influences on liver injury after cardiopulmonary bypass (CPB). Methods This observational single center..

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Comparative spallation performance of silicone versus Tygon extracorporeal circulation tubing

Abstract OBJECTIVES Reports ranged from mixed to marginal tubing wear and spallation effects as a complication of roller pumps in cardiopulmonary bypass (CPB). Because the rollers constantly compress part of..

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The use of mannitol in cardiopulmonary bypass prime solution—Prospective randomized double‐blind clinical trial

Abstract Background The optimal prime solution for the cardiopulmonary bypass (CPB) circuit in adult cardiac surgery has not yet been defined. Mannitol is widely used in the priming solution for..

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Right atrial pressure and venous return during cardiopulmonary bypass

Abstract The relevance of right atrial pressure (RAP) as the backpressure for venous return (QVR) and mean systemic filling pressure as upstream pressure is controversial during dynamic changes of circulation...

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Inflammation and coagulation following minimally invasive extracorporeal circulation technologies

Abstract Minimally invasive extracorporeal perfusion technologies are based on the use of a minimally invasive extracorporeal circulation (MiECC) system. This includes a closed CPB circuit; biologically inert blood contact surfaces;..

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Effects of pulsatile minimal invasive extracorporeal circulation on fibrinolysis and organ protection in adult cardiac surgery—a prospective randomized trial

Abstract Background  Minimal invasive extracorporeal circulation (MiECC) reduces the impact of cardiopulmonary bypass during cardiac surgery on inflammation and hemostasis. Pulsatile perfusion may enhance organ perfusion and help to prevent..

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Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Abstract Background Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier..

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Effect of high- versus low-volume saline administration on acute kidney injury after cardiac surgery

Abstract Background: Fluid resuscitation is critical to perioperative maintenance of adequate preload and cardiac output after cardiac surgery. Liberal use of saline, however, is reportedly associated with an increased risk of..

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The cardiopulmonary bypass and cancer dissemination puzzle

Abstract Early cancer diagnosis, new therapies that increased survival of patients, besides the increasingly elderly population are some factors would be associated with possible cancer dissemination in patients under cardiopulmonary..

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Novel method for estimating the total blood volume: the importance of adjustment using the ideal body weight and age for…

Abstract OBJECTIVES Although total blood volume (TBV) is central to the estimation of the haemodilution rate during cardiopulmonary bypass (CPB), conventional formulas lack sufficient accuracy. The aim of this study..

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Audit of transfusion of blood products in paediatric congenital heart surgery on cardiopulmonary bypass

Abstract Background: Cardiac surgery is associated with peri-operative bleeding, which may result in the need for blood transfusion, particularly in paediatric congenital cardiac surgery on cardiopulmonary bypass (CPB). There is..

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Effects of cardiopulmonary bypass on the disposition of cefazolin in patients undergoing cardiothoracic surgery

Abstract The aim of the study was to evaluate the disposition of plasma unbound cefazolin in patients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB). Adult patients undergoing cardiothoracic surgery with..

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Is the Cardiopulmonary Bypass Systemic Inflammatory Response Overestimated?

Abstract According to a survey by the University of Ottawa in 2009, we have surpassed the 50 million mark over the total number of scientific articles published since 1665, and..

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