Tags Archives: cardiopulmonary bypass (CPB)

Perfusfind S.L.

Abstract Objective Neurodevelopmental delays and frontal lobe cortical dysmaturation are widespread among children with congenital heart disease (CHD). The subventricular zone (SVZ) is the largest pool of neural stem/progenitor cells..

Perfusfind S.L.

Abstract Introduction Cardiopulmonary bypass (CPB) is currently performed in infants and newborns for surgical correction of congenital heart diseases (CHDs).1 CPB exposes the body to extreme, nonphysiologic conditions that initiate a..

Perfusfind S.L.

Abstract Backgroundː Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its occurrence and associations with outcomes. The objective of this..

Perfusfind S.L.

Abstract Introduction: To our knowledge, methylprednisolone pharmacokinetics and plasma concentrations have not been comprehensively investigated in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. It is unknown whether..

Perfusfind S.L.

Abstract Introduction Weaning from cardiopulmonary bypass (CPB) is a critical step of any cardiac surgical procedure and often requires pharmacologic intervention. Calcium ions are pivotal elements for the excitation-contraction coupling..

Perfusfind S.L.

Abstract Objectives Patients after cardiac surgery with  (CPB) require a stay in the ICU postoperatively. This study aimed to investigate the incidence of prolonged length of stay (LOS) in the ICU..

Perfusfind S.L.

Abstract Objectives The aim was to evaluate changes in the coagulation profile of cyanotic neonates, to analyze the effects of cardiopulmonary bypass (CPB) with crystalloid priming on their coagulation status,..

Perfusfind S.L.

Abstract Introduction: Modified ultrafiltration (MUF) is employed at the termination of cardiopulmonary bypass (CPB) in pediatric and neonatal patients undergoing congenital heart surgery to reduce the accumulation of total body..

Perfusfind S.L.

Inspire is a complete family of adult oxygenators designed from years of research and laboratory experience, input from clinical experts from around the world and the application of advanced manufacturing..

Perfusfind S.L.

Abstract Background Elevated plasma free hemoglobin is associated with multi-organ injury. In this context, minimally invasive extracorporeal technologies represent a way to reduce this complication following cardiac surgery. Methods We..

Perfusfind S.L.

Abstract Purpose of Review Cardiopulmonary bypass for on-pump cardiac surgery induces a systemic inflammation that may contribute to postoperative major complications. To reduce this inflammatory response in patients undergoing heart..

Perfusfind S.L.

Abstract Background Red blood cell transfusion is common and associated with adverse outcomes for cardiac surgery, while present blood conservation guidelines have not been fully implemented until now. This study..

Perfusfind S.L.

Abstract     OBJECTIVES Older patients have a higher cardiac surgery-associated acute kidney injury (CSA-AKI) related mortality. Low oxygen delivery (DO2) during cardiopulmonary bypass (CPB) is a risk factor for..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We..

Perfusfind S.L.

Abstract BACKGROUND:  Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse reaction to heparin. Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) are routinely anticoagulated with heparin before the initiation of bypass...

Perfusfind S.L.

Abstract Background： Hyperlactacidemia seriously affects the prognosis of cardiac surgery patients. This study was to explore the impact of target blood pressure management during cardiopulmonary bypass (CPB) on blood lactate..

Perfusfind S.L.

Abstract     OBJECTIVES Carbon dioxide (CO2) gas insufflation is used for continuous de-airing during open heart surgery. The aim was to evaluate if an additional separate venous reservoir eliminates..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is a well-known complication after cardiac surgery and cardiopulmonary bypass (CPB). In the present secondary analysis of a blinded randomized controlled trial, we evaluated..

Perfusfind S.L.

Abstract Objectives This study aimed to investigate which factors have a great impact on coagulopathy after cardiopulmonary bypass (CPB) using rotational thromboelastometry (ROTEM). Methods Ninety-eight patients undergoing cardiovascular surgery using..

Perfusfind S.L.

Abstract The Priming volume of the oxygenators has been reduced by 75% during the last two decades and it is now possible to go safely on bypass with a priming..

Perfusfind S.L.

Abstract Protamine is mainly used to reverse the anticoagulant effect of heparin after cardiopulmonary bypass (CPB). Unfortunately, it is associated with adverse clinical reactions ranging from minor cardiopulmonary instability to..

Perfusfind S.L.

Abstract Introduction To assess the efficacy of C-reactive protein (CRP) and procalcitonin (PCT) at identifying infection in children after congenital heart surgery (CHS) with cardiopulmonary bypass (CPB). Materials and Methods..

Perfusfind S.L.

Abstract Background Oxygen delivery during cardiopulmonary bypass (CPB) is closely related to postoperative acute kidney injury (AKI). The value of critical indexed oxygen delivery (DO2i) is a key indicator to..

Perfusfind S.L.

Abstract During cardiopulmonary bypass (CPB), high flows can allow an adequate perfusion to kidneys, but, on the other hand, they could cause emboli production, increased vascular pressure, and a more..

Perfusfind S.L.

Abstract Background: Myocardial preconditioning using volatile anesthetics such as isoflurane and sevoflurane have beneficial effects in decreasing morbidity in cardiac surgical patients. Studies in animal models have indicated that reactive oxygen..

Perfusfind S.L.

Abstract Background: The purpose of the present systematic review was to evaluate the incidence, risk factors, and outcome of hyperbilirubinemia after cardiac surgery. Methods: The Population, Interventions, Comparators, Outcomes, and Study design..

Perfusfind S.L.

Abstract Introduction Cytokine storm and endotoxin release during cardiac surgery with cardiopulmonary bypass (CPB) have been related to vasoplegic shock and organ dysfunction. We hypothesised that early (during CPB) cytokine adsorption..

Perfusfind S.L.

Abstract Background: Current diagnostic strategies for acute kidney injury (AKI) after cardiac surgery with cardiopulmonary bypass (CPB) are nonspecific and limited. Previously, we demonstrated that circulating microparticles (MPs) in patients with..

Perfusfind S.L.

Example of multiple Y grafts for total epicardial vessels revascularisation as you can see despite 6 grafts just two proximal anastomoses in the ascending aorta. Another type of SVG transverse..

Perfusfind S.L.

Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..