Tags Archives: cardiac surgery

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Role of Platelet Function Test in Predicting Postoperative Bleeding Risk after Coronary Artery Bypass Grafting: A Prospective Observational Study

Abstract Patients undergoing cardiac surgery are at risk of excessive bleeding and its associated complications. Excessive bleeding during and after cardiac surgery has an incidence of ~20%. Massive bleeding and..

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The Effect of COVID-19 on Adult Cardiac Surgery in the United States in 717,103 Patients

Abstract Background: COVID-19 has changed the world as we know it, and the United States continues to accumulate the largest number of COVID-related deaths worldwide. There exists a paucity of data..

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Dissecting Cardiac Surgery

Abstract Objective:  The aim of this study was to elucidate the cognitive processes involved in surgical procedures from the perspective of different team roles (surgeon, anesthesiologist, and perfusionist) and provide..

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Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

The outbreak of severe acute respiratory syndrome-coronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide. It has..

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Haemostasis in Cardiac Surgery

Abstract The following sections are included: HISTORICAL NOTE DYNAMICS OF COAGULATION, FIBRINOLYSIS, AND COMPLEMENT ACTIVATION CARDIOPULMONARY BYPASS (CPB) Role of Oxygenators in Haemostasis   ANTI-COAGULATION DURING CARDIOPULMONARY BYPASS Heparin Protamine..

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Early prediction of acute kidney injury in neonates with cardiac surgery

Abstract Background  Acute kidney injury (AKI) occurs in 42%–64% of the neonatal patients experiencing cardiac surgery, contributing to postoperative morbidity and mortality. Current diagnostic criteria, which are mainly based on..

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CIRP Secretion during Cardiopulmonary Bypass Is Associated with Increased Risk of Postoperative Acute Kidney Injury

Abstract Background  Systemic inflammation contributes to cardiac surgery–associated acute kidney injury (AKI). Cardiomyocytes and other organs experience hypothermia and hypoxia during cardiopulmonary bypass (CPB), which induces the secretion of cold-inducible..

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Oxidative stress response in children undergoing cardiac surgery: Utility of the clearance of isoprostanes

Abstract Introduction Cardiac surgery (CS) in pediatric patients induces an overt oxidative stress (OS) response. Children are particularly vulnerable to OS related injury. The immaturity of their organs and antioxidant..

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A tool to assess nontechnical skills of perfusionists in the cardiac operating room

Abstract Objectives This study aimed to develop the Perfusionists' Intraoperative Non-Technical Skills tool, specifically to the perfusionists' context, and test its inter-rater reliability. Methods An expert panel was convened to..

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The role of hydrocortisone pre-treatment in decreasing side effects of protamine sulfate administration during cardiac surgery: a randomised controlled trial

Abstract Background One of the challenges during cardiac surgery is to keep patients fully anticoagulated during the  time and reversing  at the end of surgery. For that purpose, heparin and its approved..

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Patient blood management in cardiac surgery: The “Granducato algorithm”

Abstract Background Patients undergoing cardiac surgery are subject to severe alterations of the coagulation system. The four cardiac surgery centers in Tuscany (Italy) structured and shared an algorithm (Granducato Patient..

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The Albumin-to-Fibrinogen Ratio Independently Predicts Acute Kidney Injury in Infants With Ventricular Septal Defect Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..

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Procalcitonin and Early Postoperative Infection After Pediatric Cardiopulmonary Bypass Surgery

Abstract Objectives Systemic inflammation and bacterial infections are critical occurrences after pediatric cardiac surgery. Elevated white blood cell count and C-reactive protein cannot discriminate between these two conditions in the..

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Pro-Con Debate: Fibrinogen Concentrate or Cryoprecipitate for Treatment of Acquired Hypofibrinogenemia in Cardiac Surgical Patients

Abstract Cryoprecipitate has been the gold standard for treating acquired hypofibrinogenemia in cardiac surgery for nearly 50 years. More recently, fibrinogen concentrate has been used off-label in the United States..

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Biomarkers of Cerebral Injury for Prediction of Postoperative Cognitive Dysfunction in Patients Undergoing Cardiac Surgery

Abstract Objectives To assess the ability of the biomarkers neuron-specific enolase (NSE), tau, neurofilament light chain (NFL), and glial fibrillary acidic protein (GFAP) to predict postoperative cognitive dysfunction (POCD) at..

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A Nomogram to Predict Acute Respiratory Distress Syndrome After Cardiac Surgery

Abstract Purpose: To establish a model to predict the risk of acute respiratory distress syndrome (ARDS) after cardiac surgery. Methods: Data were collected on 132 ARDS patients, who received valvular or coronary..

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Comparison of postoperative delirium within 24 hours between ketamine and propofol infusion during cardiopulmonary bypass machine: A randomized controlled trial

Abstract Background:  Postoperative delirium (POD) is a common complication in cardiac surgery especially in elderly population which can lead to a delay of weaning from ventilator and extubation. Cardiopulmonary bypass..

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Con: Routine Use of Fresh Frozen Plasma Should Not Be Used to Prime Cardiopulmonary Bypass Circuits During Cardiac Surgery

Abstract BLEEDING is a well-documented and frequently encountered complication after cardiac surgery, affecting roughly 2%-to-10% of all patients.  Major bleeding is a known risk factor for significant morbidity and mortality..

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Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery

Abstract Objectives The objective of this study was to identify novel serum biomarkers specific to postoperative delirium after major cardiac surgery to provide insight into the pathologic processes involved in..

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Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..

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Hyponatremia: An Overlooked Risk Factor Associated With Adverse Outcomes After Cardiac Surgery

Abstract Background  is an unrecognized risk factor for  after cardiac surgery. We sought to study the prevalence of preoperative hyponatremia and its impact on short-term and long-term outcomes after cardiac surgery...

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Patient characteristics and cardiac surgical outcomes at a tertiary care hospital in Kenya, 2008–2017: a retrospective study

Abstract Background Cardiac surgeries are high risk procedures that require specialized care and access to these procedures is often limited in resource-poor countries. Although fatalities for surgical patients across Africa..

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Retrograde autologous priming during cardiopulmonary bypass reduces blood transfusion rate in adult cardiac surgery: A prospective randomized clinical trial

Abstract To the editor, Retrograde autologous priming (RAP) is a non-drug blood protection method to reduce blood dilution by lowering the amount of crystal liquid priming., ,  But there is no unified..

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Risk factors for vasoplegia after coronary artery bypass and valve surgery

Abstract Introduction Vasoplegia denotes a state of low tissue perfusion characterized by hypotension, tachycardia, and low systemic vascular resistance. This state results in increased mortality and morbidity following cardiac surgery...

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Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

Abstract Background Approximately 20% to 30% of patients awaiting cardiac surgery are anemic. Anemia increases the likelihood of requiring a red cell transfusion and is associated with increased complications, intensive care,..

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Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac surgery

Abstract Background Acute Kidney Injury (AKI) represents a clinical condition with poor prognosis. The incidence of AKI in hospitalized patients was about 22–57%. Patients undergoing cardiac surgery (CS) are particularly..

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Elevated Arterial–Central Venous Carbon Dioxide Partial Pressure Difference Indicates Poor Prognosis in the Early Postoperative Period of Open Heart Surgery…

Abstract Background Elevated arterial–central venous carbon dioxide partial pressure difference (AVCO2) may be an important marker to predict tissue and organ hypoperfusion in adults. We analyzed the hemodynamic data of..

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Pro: Priming the Cardiopulmonary Bypass Circuit With Fresh Frozen Plasma Reduces Bleeding in Complex Cardiac Surgery

Abstract CARDIAC SURGERY is inherently complex and is associated with a high risk of perioperative bleeding. As such, it is responsible for a disproportionate percentage of annual blood product usage..

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The impact of team familiarity on intra and postoperative cardiac surgical outcomes

Abstract Background Familiarity among cardiac surgery team members may be an important contributor to better outcomes and thus serve as a target for enhancing outcomes. Methods Adult cardiac surgical procedures..

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Dynamic responses of renal oxygenation at the onset of cardiopulmonary bypass in sheep and man

Abstract Introduction: The renal medulla is susceptible to hypoxia during cardiopulmonary bypass (CPB), which may contribute to the development of acute kidney injury. But the speed of onset of renal..

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