Tags Archives: cardiac surgery

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) in infants is associated with morbidity due to systemic inflammatory response syndrome (SIRS). Strategies to mitigate SIRS include management of perfusion temperature, hemodilution, circuit miniaturization, and..

Perfusfind S.L.

Abstract Advances in cardiopulmonary bypass equipment have played a critical role in improving outcomes for cardiac surgery patients. Recent advancements include reduced priming volumes, biocompatible coatings and gaseous microemboli handling,..

Perfusfind S.L.

Abstract Background Levosimendan has been shown to confer direct renoprotection in renal endotoxemic and ischemia-reperfusion injury and could increase renal blood flow in patients with low-cardiac-output heart failure. Results from..

Perfusfind S.L.

Abstract Neurologic injury in the form of cognitive decline, delirium, and stroke are common phenomena in patients undergoing cardiac surgery and continues to be one of the most common complication..

Perfusfind S.L.

Abstract Blood transfusion is the most common procedure in cardiac surgery. Increasing evidence exists that excess transfusions are harmful to patients. Transfusion reactions and complications, including infection, immune modulation, and..

Perfusfind S.L.

Abstract Anemia is an common condition in patients undergoing cardiac surgery, and it is often present in one quarter to half of patients at admission. Several studies have indicated that..

Perfusfind S.L.

Abstract Objectives To estimate the global incidence and outcomes of  (AKI) after cardiac surgery in adult patients. Design A systematic review and meta-analysis. Setting Cardiac surgery wards. Participants Adult patients after..

Perfusfind S.L.

Abstract Post-cardiotomy extracorporeal life support (PC-ECLS) in adult patients has been used only rarely but recent data have shown a remarkable increase in its use, almost certainly due to improved..

Perfusfind S.L.

Abstract Introduction. During the past five years the approach to procedural planning, operative techniques and perfusion strategies for minimally invasive mitral valve surgery (MIMVS) has evolved. With the goal to..

Perfusfind S.L.

Abstract Objective Postoperative  is a frequent and serious consequence of cardiac surgery. We undertook to investigate the association of obesity and the risk of acute kidney injury development after cardiac surgery...

Perfusfind S.L.

Abstract Cardiac surgical outcomes in the UK have consistently improved despite increasing procedure complexity and ‘sicker’ patients. Numerous anaesthetic techniques are employed with no definitive evidence clearly demonstrating superiority of..

Perfusfind S.L.

Abstract BACKGROUND:  Hypomagnesemia has been associated with an increased risk of postoperative atrial fibrillation (POAF). Although previous studies have suggested a beneficial effect of magnesium (Mg) therapy, almost all of..

Perfusfind S.L.

Abstract Objective Remote  (RIPC) exerts  effects in models of cerebral . The authors tested the hypothesis that RIPC decreases the incidence of  and prevents deterioration of short-term postoperative cognitive function in isoflurane-fentanyl-anesthetized patients undergoing..

Perfusfind S.L.

Abstract Excessive haemodilution and the resulting anaemia during CPB is accompanied by a decrease in the total arterial oxygen content, which may impair tissue oxygen delivery. Hyperoxic ventilation has been..

Perfusfind S.L.

Abstract , a , has recently emerged as a valuable agent in the peri-operative management of cardiac surgery patients. Levosimendan is a calcium-sensitising ionodilator. By binding to  C and reducing its  co-efficient, it..

Perfusfind S.L.

Abstract Background The impact of transfusion of aged red blood cells (RBCs) on the outcome after  (CABG) is controversial. This issue has been investigated in the present study. Materials and methods..

Perfusfind S.L.

Abstract Objective To assess whether the administration of the ultra-short–acting β-blocker esmolol in cardiac surgery could have a cardioprotective effect that translates into improved postoperative outcomes. Design Single-center, double-blinded, parallel-group..

Perfusfind S.L.

Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited...

Perfusfind S.L.

Abstract Background Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) are thought to be at the origin of organ dysfunction, although few studies have correlated microvascular alterations with outcome...

Perfusfind S.L.

Abstract Background Severe post‐operative bleeding in cardiac surgery is associated with increased morbidity and mortality. We hypothesized that variation in genetic susceptibility contributes to post‐operative bleeding in addition to clinical..

Perfusfind S.L.

Abstract Purpose of review  To provide an update of research findings regarding the protection strategies utilized for patients undergoing cardiopulmonary bypass (CPB), including perioperative ventilatory strategies, different anesthetic regimens, and..

Perfusfind S.L.

Abstract Summary To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity..

Perfusfind S.L.

Abstract Objectives During cardiac surgery, circulating red blood cells (RBCs) are at risk of exposure to environmental factors during  and transfusion of stored RBCs. For this study, the authors observed morphological..

Perfusfind S.L.

Abstract Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical patients in association with patient (advanced age,..

Perfusfind S.L.

Abstract Introduction Genetic polymorphisms are important in explaining the wide interpatient variability that exists in the development of acute kidney injury (AKI) post cardiac surgery. We hypothesised that polymorphisms in..

Perfusfind S.L.

Abstract OBJECTIVES: The upcoming release of aprotinin in paediatric cardiac surgery prompted a re-evaluation of its use in comparison to tranexamic acid (TXA) focusing on their effect on exposure to..

Perfusfind S.L.

Abstract OBJECTIVES Although reduced lung function and chronic obstructive pulmonary disease (COPD) is associated with higher risk of death following cardiac surgery, preoperative spirometry is not performed routinely. The aim..

Perfusfind S.L.

Abstract OBJECTIVES Between 2% and 8% of patients return to the theatre for mediastinal bleeding following cardiac surgery. In the majority of patients, a surgical source of bleeding is identified...

Perfusfind S.L.

Abstract Objectives Prolonged  (CPB) is recognized as a risk factor for  (ARF), but the dose effect of time on bypass is unknown. We therefore examined the risk of ARF associated with increasing..

Perfusfind S.L.

Abstract Malignant hyperthermia is a well-known but potentially lethal disorder which is triggered by volatile anesthetics and depolarizing muscle relaxants. Early diagnosis and treatment could save lives. However, during cardiac..