Tags Archives: cardiac arrest

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Hypothermia in patients with cardiac arrest prior to ECMO-VA: Insight from the HYPO-ECMO trial

Abstract Aim Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has become a common intervention for patients with cardiogenic shock (CS), often complicated by cardiac arrest (CA). Moderate hypothermia (MH) has shown promise..

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Intraoperative circulatory arrest secondary to high-risk pulmonary embolism. Case series and updated literature review

Abstract Background Intraoperative pulmonary embolism (PE) with cardiac arrest (CA) represents a critical and potentially fatal condition. Available treatments include systemic thrombolysis, catheter-based thrombus fragmentation or aspiration, and surgical embolectomy...

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Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: an updated meta‑analysis and trial sequential analysis

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) may reduce mortality and improve neurological outcomes in patients with cardiac arrest. We updated our existing meta-analysis and trial sequential analysis to further evaluate..

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2023 American Heart Association Focused Update on Adult Advanced Cardiovascular Life Support: An Update to the American Heart Association Guidelines…

Abstract Cardiac arrest is common and deadly, affecting up to 700 000 people in the United States annually. Advanced cardiac life support measures are commonly used to improve outcomes. This “2023..

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Accredited cardiac arrest centers facilitate eCPR and improve neurological outcome

Abstract Background Out-of-hospital cardiac arrest (OHCA) remains a frequent medical emergency with low survival rates even after a return of spontaneous circulation (ROSC). Growing evidence supports formation of dedicated teams..

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The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations

Abstract Purpose: The 2021 guidelines endorsed by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) recommend using highly malignant electroencephalogram (EEG) patterns (HMEP; suppression..

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Impact of age on survival for patients receiving ECPR for refractory out-of-hospital VT/VF cardiac arrest

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival for patients with refractory ventricular tachycardia (VT)/ventricular fibrillation (VF) out-of-hospital cardiac arrest. Prior studies of the impact of age..

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Levosimendan in extracorporeal membrane oxygenation in refractory cardiac arrest

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can re-establish tissue perfusion in refractory cardiac arrest requiring cardiopulmonary resuscitation (CPR). Levosimendan showed potential benefit in VA-ECMO weaning and mortality but was not..

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Albumin Infusion Reduces Fluid Loading for Postresuscitation Syndrome in a Pig Model of Refractory Cardiac Arrest Resuscitated With Venoarterial Extra…

Abstract Hemodynamic instability in postresuscitation syndrome worsens survival and neurological outcomes. Venoarterial extracorporeal membrane oxygenation (VA ECMO) for refractory cardiac arrest might improve outcomes. Hemodynamical support under VA ECMO relies..

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Children who suffer cardiac arrest more likely to survive at ECMO capable hospitals

Abstract Children who experience cardiac arrest are one and a half times more likely to survive at a hospital capable of providing the life support system called ECMO, research suggests...

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Mechanical life support algorithm for the emergency management of patients with left-sided Impella

Abstract We sought to remedy the limited guidance that is available to support the resuscitation of patients with the Impella Cardiac Power (CP) and 5.0 devices during episodes of cardiac..

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Cardiac arrest and cardiopulmonary resuscitation in pediatric patients with cardiac disease: a narrative review

Abstract Children with cardiac disease are at a higher risk of cardiac arrest as compared to healthy children. Delivering adequate cardiopulmonary resuscitation (CPR) can be challenging due to anatomic characteristics,..

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Hospital ECMO capability is associated with survival in pediatric cardiac arrest

Abstract Aim Extracorporeal membrane oxygenation (ECMO) provides temporary support in severe cardiac or respiratory failure and can be deployed in children who suffer cardiac arrest. However, it is unknown if..

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Extracorporeal Cardiopulmonary Resuscitation for Cardiac Arrest

Abstract Cardiac arrest affects approximately 600 000 people in the US yearly and is associated with a survival rate of 10% to 12% for out-of-hospital cardiac arrests and 25% to 30%..

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Higher mean cerebral oxygen saturation shortly after extracorporeal cardiopulmonary resuscitation in patients who regain consciousness

Abstract Introduction In cardiac arrest, cerebral ischaemia and reperfusion injury mainly determine the neurological outcome. The aim of this study was to investigate the relation between the course of cerebral..

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Low-Flow Duration and Outcomes of Extracorporeal Cardiopulmonary Resuscitation in Adults With In-Hospital Cardiac Arrest: A Nationwide Inpatient Database Study

Abstract OBJECTIVES:  Although existing guidelines recommend commencing cannulation for extracorporeal cardiopulmonary resuscitation (ECPR) within 10–20 minutes of failed conventional resuscitation efforts for cardiac arrest, there is little supportive evidence. The present study..

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Mechanical life support algorithm for emergency management of patient receiving extracorporeal membrane oxygenation

Abstract Background There are limited practical advanced life support algorithms to aid teams in the management of cardiac arrest in patients on extracorporeal membrane oxygenation (ECMO). Methods In our specialist..

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Refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: A meta-analysis of randomized trials

Abstract Background In adults with refractory out-of-hospital cardiac arrest, when conventional cardiopulmonary resuscitation (CPR) alone does not achieve return of spontaneous circulation, extracorporeal CPR is attempted to restore perfusion and..

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Out-of-hospital cardiac arrest

Abstract Cardiac arrest science continues to evolve and in the last two years many cardiac arrest clinical trials have been published in high-impact journals. In this manuscript we have selected 6..

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Successful percutaneous coronary intervention with extracorporeal membrane oxygenation in a patient with acute inferior wall myocardial infarction complicated by electrical…

Abstract Background High-risk patients with coronary heart disease who develop acute myocardial infarction (AMI) have severe coronary lesions. If severe complications occur, such as malignant ventricular arrhythmia, cardiogenic shock, and..

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Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest

Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on..

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Variation in Survival After Cardiopulmonary Arrest in Cardiac Catheterization Laboratories in the United States

Abstract Background In-hospital cardiac arrest during cardiac catheterization is not uncommon. The extent of variation in survival after cardiac arrest occurring in the cardiac catheterization laboratory (CCL) and underlying factors..

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Extracorporeal Membrane Oxygenation Cannulation Timing in the Pediatric Myocarditis Population: An Exploratory Analysis From the Extracorporeal Life Support Organization Registry

Abstract OBJECTIVES:  Children presenting with acute myocarditis may experience rapid clinical deterioration requiring extracorporeal membrane oxygenation (ECMO); however, our understanding of best practices and timing of ECMO initiation are lacking...

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Outcome of extracorporeal membrane oxygenation use in severe accidental hypothermia with cardiac arrest and circulatory instability: A multicentre, prospective, observational…

Abstract Aim To elucidate the effectiveness of extracorporeal membrane oxygenation (ECMO) in accidental hypothermia (AH) patients with and without cardiac arrest (CA), including details of complications. Methods This study was..

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Enabling the control of reperfusion parameters in out-of-hospital cardiac arrest: First applications of the CARL system

Abstract Introduction There is increasing evidence for extracorporeal cardiopulmonary resuscitation (ECPR) as a rescue therapy for selected patients in refractory cardiac arrest (CA). Besides patient selection, the control of reperfusion..

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Dutch trial set out to save more lives using Getinge’s Cardiohelp in prehospital care

Abstract A nationwide trial has kicked off in the Netherlands as four Mobile Medical Teams join forces to offer extracorporeal cardiopulmonary resuscitation (ECPR) as rescue therapy for refractory out-of-hospital cardiac arrest...

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Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest

Abstract Importance  The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. Objective  To determine whether targeting a lower oxygen..

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Cost-effectiveness of extracorporeal cardiopulmonary resuscitation after in-hospital cardiac arrest: A Markov decision model

Abstract Background: This study aimed to estimate the cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital cardiac arrest treatment. Methods: A decision tree and Markov model were constructed based on current literature...

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Contemporary targeted temperature management: Clinical evidence and controversies

Abstract Advancements in cardiac arrest and post-cardiac arrest care have led to improved survival to hospital discharge. While survival to hospital discharge is an important clinical outcome, neurologic recovery is..

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Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest: A Systematic Review and Meta-Analysis

Abstract The survival rate after cardiac arrest (CA) remains low. The utilization of extracorporeal life support is proposed to improve management. However, this resource-intensive tool is associated with complications and..

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