Tags Archives: cardiac arrest

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Hospital ECMO capability is associated with survival in pediatric cardiac arrest

Abstract Aim Extracorporeal membrane oxygenation (ECMO) provides temporary support in severe cardiac or respiratory failure and can be deployed in children who suffer cardiac arrest. However, it is unknown if..

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Extracorporeal Cardiopulmonary Resuscitation for Cardiac Arrest

Abstract Cardiac arrest affects approximately 600 000 people in the US yearly and is associated with a survival rate of 10% to 12% for out-of-hospital cardiac arrests and 25% to 30%..

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Higher mean cerebral oxygen saturation shortly after extracorporeal cardiopulmonary resuscitation in patients who regain consciousness

Abstract Introduction In cardiac arrest, cerebral ischaemia and reperfusion injury mainly determine the neurological outcome. The aim of this study was to investigate the relation between the course of cerebral..

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Low-Flow Duration and Outcomes of Extracorporeal Cardiopulmonary Resuscitation in Adults With In-Hospital Cardiac Arrest: A Nationwide Inpatient Database Study

Abstract OBJECTIVES:  Although existing guidelines recommend commencing cannulation for extracorporeal cardiopulmonary resuscitation (ECPR) within 10–20 minutes of failed conventional resuscitation efforts for cardiac arrest, there is little supportive evidence. The present study..

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Mechanical life support algorithm for emergency management of patient receiving extracorporeal membrane oxygenation

Abstract Background There are limited practical advanced life support algorithms to aid teams in the management of cardiac arrest in patients on extracorporeal membrane oxygenation (ECMO). Methods In our specialist..

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Refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: A meta-analysis of randomized trials

Abstract Background In adults with refractory out-of-hospital cardiac arrest, when conventional cardiopulmonary resuscitation (CPR) alone does not achieve return of spontaneous circulation, extracorporeal CPR is attempted to restore perfusion and..

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Out-of-hospital cardiac arrest

Abstract Cardiac arrest science continues to evolve and in the last two years many cardiac arrest clinical trials have been published in high-impact journals. In this manuscript we have selected 6..

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Successful percutaneous coronary intervention with extracorporeal membrane oxygenation in a patient with acute inferior wall myocardial infarction complicated by electrical…

Abstract Background High-risk patients with coronary heart disease who develop acute myocardial infarction (AMI) have severe coronary lesions. If severe complications occur, such as malignant ventricular arrhythmia, cardiogenic shock, and..

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Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest

Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on..

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Variation in Survival After Cardiopulmonary Arrest in Cardiac Catheterization Laboratories in the United States

Abstract Background In-hospital cardiac arrest during cardiac catheterization is not uncommon. The extent of variation in survival after cardiac arrest occurring in the cardiac catheterization laboratory (CCL) and underlying factors..

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Extracorporeal Membrane Oxygenation Cannulation Timing in the Pediatric Myocarditis Population: An Exploratory Analysis From the Extracorporeal Life Support Organization Registry

Abstract OBJECTIVES:  Children presenting with acute myocarditis may experience rapid clinical deterioration requiring extracorporeal membrane oxygenation (ECMO); however, our understanding of best practices and timing of ECMO initiation are lacking...

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Outcome of extracorporeal membrane oxygenation use in severe accidental hypothermia with cardiac arrest and circulatory instability: A multicentre, prospective, observational…

Abstract Aim To elucidate the effectiveness of extracorporeal membrane oxygenation (ECMO) in accidental hypothermia (AH) patients with and without cardiac arrest (CA), including details of complications. Methods This study was..

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Enabling the control of reperfusion parameters in out-of-hospital cardiac arrest: First applications of the CARL system

Abstract Introduction There is increasing evidence for extracorporeal cardiopulmonary resuscitation (ECPR) as a rescue therapy for selected patients in refractory cardiac arrest (CA). Besides patient selection, the control of reperfusion..

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Dutch trial set out to save more lives using Getinge’s Cardiohelp in prehospital care

Abstract A nationwide trial has kicked off in the Netherlands as four Mobile Medical Teams join forces to offer extracorporeal cardiopulmonary resuscitation (ECPR) as rescue therapy for refractory out-of-hospital cardiac arrest...

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Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest

Abstract Importance  The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. Objective  To determine whether targeting a lower oxygen..

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Cost-effectiveness of extracorporeal cardiopulmonary resuscitation after in-hospital cardiac arrest: A Markov decision model

Abstract Background: This study aimed to estimate the cost-effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for in-hospital cardiac arrest treatment. Methods: A decision tree and Markov model were constructed based on current literature...

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Contemporary targeted temperature management: Clinical evidence and controversies

Abstract Advancements in cardiac arrest and post-cardiac arrest care have led to improved survival to hospital discharge. While survival to hospital discharge is an important clinical outcome, neurologic recovery is..

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Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest: A Systematic Review and Meta-Analysis

Abstract The survival rate after cardiac arrest (CA) remains low. The utilization of extracorporeal life support is proposed to improve management. However, this resource-intensive tool is associated with complications and..

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Hypothermic versus Normothermic Temperature Control after Cardiac Arrest

Abstract BACKGROUND The evidence for temperature control for comatose survivors of cardiac arrest is inconclusive. Controversy exists as to whether the effects of hypothermia differ per the circumstances of the..

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Clinical outcomes among out-of-hospital cardiac arrest patients treated by extracorporeal cardiopulmonary resuscitation: the CRITICAL study in Osaka

Abstract Aim Extracorporeal cardiopulmonary resuscitation (ECPR) is performed in refractory out-of-hospital cardiac arrest (OHCA) patients, and the eligibility has been conventionally determined based on three criteria (initial cardiac rhythm, time..

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Predictors of Survival and Favorable Neurologic Outcome in Patients Treated with eCPR: a Systematic Review and Meta-analysis

Abstract Extracorporeal cardiopulmonary resuscitation (eCPR) can improve survival in selected patients with cardiac arrest (CA). In this meta-analysis, we evaluated factors associated with short-term survival and favorable neurologic outcome (FNO)..

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The effect of a structured ECPR protocol aided by specific simulation training in a quaternary ECMO centre: A retrospective pre-post…

Abstract Background There is limited literature exploring the relationship between simulation training and  cardiopulmonary resuscitation (ECPR) outcomes. We examined whether there was an association between the implementation of an  training program and..

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Induced Hypothermia to as Cold as 3°C in Humans: Forgotten Cases Rediscovered

Abstract Zafren, Ken, Raimund Lechner, Peter Paal, Hermann Brugger, Giles Peek, and Tomasz Darocha. Induced hypothermia to as cold as 3°C in humans: Forgotten cases rediscovered. High Alt Med Biol. 22:000–000, 2021...

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A review of ECMO for cardiac arrest

Abstract Cardiac arrest is an important public health concern, affecting an estimated 356,500 people in the out-of-hospital setting and 209,000 people in the in-hospital setting each year. The causes of..

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ECMO in Cardiac Arrest: A Narrative Review of the Literature

Abstract Cardiac arrest (CA) is a frequent cause of death and a major public health issue. To date, conventional cardiopulmonary resuscitation (CPR) is the only efficient method of resuscitation available..

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Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

Abstract BACKGROUND Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS In an open-label trial with blinded assessment of outcomes,..

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How effective is extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest? A systematic review and meta-analysis

Abstract Background  cardiopulmonary resuscitation (ECPR) has gained increasing as a promising but resource-intensive intervention for out-of-hospital cardiac arrest (OHCA). There is little data to quantify the impact of this intervention..

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Resuscitation Using ECPR During In-Hospital Cardiac Arrest (RESCUE-IHCA) Mortality Prediction Score and External Validation

Abstract Objectives The aim of this study was to develop and validate a score to accurately predict the probability of death for adult extracorporeal cardiopulmonary resuscitation (ECPR). Background ECPR is..

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Adrenaline improves regional cerebral blood flow, cerebral oxygenation and cerebral metabolism during CPR in a porcine cardiac arrest model using…

Abstract Background The effects of adrenaline on cerebral blood vessels during cardiopulmonary resuscitation (CPR) are not well understood. We developed an extracorporeal CPR model that maintains constant low systemic blood..

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Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest

Abstract The survival rate after cardiac arrest (CA) remains low. The utilization of extracorporeal life support is proposed to improve management. However, this resource-intensive tool is associated with complications and..

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