Tags Archives: carbon dioxide

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The association between intraoperative end-tidal carbon dioxide and prognosis in cardiac surgery patients: a retrospective cohort study

Abstract Background To evaluate the association between intraoperative end-tidal carbon dioxide (ETCO₂) levels and clinical outcomes in patients undergoing cardiac surgery. Methods This retrospective analysis included patients who underwent cardiac..

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Transcutaneous Monitoring of Carbon Dioxide to Optimize Ventilator Weaning in At-Risk Adults After Cardiopulmonary Bypass

Abstract Background  Cardiopulmonary bypass use during surgery disrupts microcirculation, which can contribute to lung injury, particularly in patients with pulmonary comorbidities. Continuous transcutaneous carbon dioxide (CO2) monitoring assists clinicians to..

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Association between venous to arterial carbon dioxide tension gap and clinical outcome in cardiac surgery patients: A systematic review and…

Abstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..

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Association between venous to arterial carbon dioxide tension gap and clinical outcome in cardiac surgery patients: A systematic review and…

Abstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..

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Effect of Dexmedetomidine on Cerebrovascular Carbon Dioxide Reactivity During Pediatric Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objective To assess the effects of dexmedetomidine (DEX) on cerebrovascular autoregulation in children with congenital heart disease (CHD) using transcranial color-coded duplex sonography (TCCD). Design Randomized controlled trial. Setting..

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Recent Advances and Future Directions in Extracorporeal Carbon Dioxide Removal

Abstract Extracorporeal carbon dioxide removal (ECCO2R) is an emerging technique designed to reduce carbon dioxide (CO2) levels in venous blood while enabling lung-protective ventilation or alleviating the work of breathing...

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The Clinical Relevance of Carbon Dioxide Management During Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation.

Abstract Background: Management of arterial carbon dioxide tension (PaCO₂) during extracorporeal circulation is critical to maintaining physiological stability. Both cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) significantly alter natural..

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Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice

Abstract Recently, advancements in extracorporeal carbon dioxide removal (ECCO2R) technology have markedly enhanced its clinical applicability and efficacy for managing severe respiratory conditions. This review highlights critical innovations in ECCO2R,..

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Extracorporeal Organ Support for Burn-Injured Patients

Abstract As mortality relating to severe acute burn injury improves, patients are surviving longer into the critical care phase, which is commonly complicated by multisystem organ failure. Extracorporeal organ support..

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A Wearable Extracorporeal CO2 Removal System with a Closed-Loop Feedback

Abstract Extracorporeal Carbon Dioxide Removal (ECCO2R) systems support patients with severe respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes, but these procedures are limited by the complexity and..

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Is there still a place for ECCO2R?

Abstract The therapeutic target of extracorporeal carbon dioxide removal (ECCO2R) is the elimination of carbon dioxide (CO2) from the blood across a gas exchange membrane without influencing oxygenation to a clinically relevant..

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Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A…

Abstract Purpose To assess the association between fluctuations of arterial carbon dioxide early after start of  (ECMO) with  (ICH) or  (IS). Materials and methods This single-center retrospective study included patients who required ECMO..

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Carbon Dioxide Targets in Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

Abstract Target values for arterial carbon dioxide tension (PaCO2) in extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS) are unknown. We hypothesized that lower PaCO2 values on ECMO would..

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Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial – A Randomized…

Abstract Rationale: It is unclear whether extracorporeal CO2 removal (ECCO2R) can reduce the rate of intubation or the total time on invasive mechanical ventilation (IMV) in adults experiencing an exacerbation of chronic..

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Efficacy and safety of carbon dioxide insufflation for brain protection for patients undergoing planned left-sided open heart valve surgery: protocol…

Abstract Introduction Brain injury is common following open heart valve surgery. Carbon dioxide insufflation (CDI) has been proposed to reduce the incidence of brain injury by reducing the number of air..

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The Effect of Carbon Dioxide Insufflation Applied at Different Pressures and Periods on Thrombotic Factors

Abstract The aim of this experimantal study which is applied on rats, is to determine the differences on the clotting factors over the application of low and high intraabdominal pressure..

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Arterial oxygen and carbon dioxide tension and acute brain injury in extracorporeal cardiopulmonary resuscitation patients: Analysis of the extracorporeal life…

Abstract Background Acute brain injury (ABI) remains common after extracorporeal cardiopulmonary resuscitation (ECPR). Using a large international multicenter cohort, we investigated the impact of peri-cannulation arterial oxygen (PaO2) and carbon..

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Continuous field flooding versus final one-shot CO2 insufflation in minimally invasive mitral valve repair

Abstract Background Insufflation of carbon dioxide (CO2) into the operative field to prevent cerebral or myocardial damage by air embolism is a well known strategy in open-heart surgery. However, here..

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Elimination of CO2 insufflation-induced hypercapnia in open heart surgery using an additional venous reservoir

Abstract   OBJECTIVES Carbon dioxide (CO2) gas insufflation is used for continuous de-airing during open heart surgery. The aim was to evaluate if an additional separate venous reservoir eliminates CO2 insufflation-induced..

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Targeting arterial partial pressure of carbon dioxide in acute respiratory distress syndrome patients using extracorporeal carbon dioxide removal

Abstract Background A retrospective analysis of SUPERNOVA trial data showed that reductions in tidal volume to ultraprotective levels without significant increases in arterial partial pressure of carbon dioxide (PaCO2) for..

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Perioperative Continuous Noninvasive Cardiac Output Monitoring in Cardiac Surgery Patients by a Novel Capnodynamic Method

Abstract Objectives To test the clinical performance of a novel continuous noninvasive cardiac output (CO) monitoring based on expired carbon dioxide kinetics in cardiac surgery patients. Design A prospective feasibility..

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The association between end-tidal carbon dioxide and arterial partial pressure of carbon dioxide after cardiopulmonary bypass pumping in cyanotic children

Abstract Introduction: Evidence suggests the high capability of non-invasive assessment of the End-tidal carbondioxide (ETCO2) in predicting changes in arterial carbon dioxide pressure (PCO2) following major surgeries in children. We aimed..

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Elimination of CO2 insufflation-induced hypercapnia in open heart surgery using an additional venous reservoir

Abstract     OBJECTIVES Carbon dioxide (CO2) gas insufflation is used for continuous de-airing during open heart surgery. The aim was to evaluate if an additional separate venous reservoir eliminates..

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Measurement of gaseous microemboli in the prime before the initiation of cardiopulmonary bypass

Abstract Introduction: The use of cardiopulmonary bypass is associated with a risk of neurocognitive deficit caused by gaseous microemboli. Flushing the empty bypass circuit with carbon dioxide, which is more..

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Respiratory Electrodialysis. A Novel, Highly Efficient Extracorporeal CO2 Removal Technique

Abstract Rationale:  We developed an innovative, minimally invasive, highly efficient extracorporeal CO2 removal (ECCO2R) technique called respiratory electrodialysis (R-ED). Objectives:  To evaluate the efficacy of R-ED in controlling ventilation compared with..

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Assessment of Cerebral Autoregulation Patterns with Near-infrared Spectroscopy during Pharmacological-induced Pressure Changes

Abstract Background: Previous work has demonstrated paradoxical increases in cerebral oxygen saturation (ScO2) as blood pressure decreases and paradoxical decreases in ScO2 as blood pressure increases. It has been suggested that..

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