Tags Archives: blood transfusion

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Predicting intraoperative transfusion volumes of blood products in cardiovascular surgery: a retrospective study

Abstract Background and Objectives Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a..

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Hemoglobin Optimization and Transfusion Reduction Through Anemia and Iron Deficiency Correction: A Post Hoc Prospective Study in Cardiac Surgery

Abstract Objectives To assess whether systematic perioperative correction of anemia and/or iron deficiency (ID) improves hemoglobin (Hb) levels and reduces transfusion requirements in elective cardiac surgery. Design Post hoc analysis..

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Predictive Power of the Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion Score for Cardiac Surgery–Associated Acute Kidney Injury:…

Abstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..

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Anaemia and blood transfusion in cardiac surgery with infective endocarditis

Abstract Background Up to half of patients with infective endocarditis (IE) require cardiac surgery. Although anaemia is common, its precise prevalence, transfusion practices and impact on outcomes in surgically treated IE..

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Reduced risk of perioperative blood transfusions in coronary surgery: A nationwide study over 18 years

Abstract Background Coronary artery bypass grafting (CABG) carries a high risk of bleeding and allogeneic blood transfusions, both associated with poor outcomes. We assessed perioperative transfusions and factors associated with..

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Crossing the line: blood transfusion thresholds in ECMO

Abstract In the high-stakes realm of extracorporeal membrane oxygenation (ECMO), every decision can have profound consequences—from initiation to termination. Management controversies persist throughout the entire course. Beyond patient selection, timing,..

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Effect of intraoperative cell salvage on postoperative blood transfusion demand outcomes in cesarean section with placenta previa: a retrospective study…

Abstract Background This study aimed to analyze the postoperative blood transfusion demand and safety of intraoperative cell salvage (ICS) without leukocyte depletion filters in cesarean sections complicated by placenta previa...

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Risk factors associated with the use of red blood cells in elective cardiac surgeries: A patient blood management (PBM) view

Abstract Background Blood is a biological, irreplaceable, and perishable resource, provided through voluntary, altruistic, and free donation in Brazil. Although blood components are widely used in hospital settings, several challenges..

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Evolving perspectives on blood transfusion in obstetric hemorrhage: a narrative review

Abstract Globally, postpartum hemorrhage is still among the most significant factors in preventable maternal morbidity and mortality. Although early recognition and intervention have improved with advances in obstetric care, transfusion..

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The evolution of artificial red blood cells and recent advances in state-of-the-art oxygen carrier technologies: a narrative review

Abstract The demand for homologous blood transfusions has reached an unprecedented level, driven by a declining donor population and the ever-increasing need for blood products. While significant advancements have been..

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The Effect of Autologous Blood Transfusion in Open Heart Procedures on the Requirement of Allogeneic Blood Products

Abstract Objectives The aim of the study was to evaluate the effect of autologous blood transfusion on the requirement of allogeneic blood products and the change in hemoglobin levels in..

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Liberal or restrictive transfusion for veno-arterial extracorporeal membrane oxygenation patients: a target trial emulation using the OBLEX study data

Abstract Background The optimal transfusion threshold for patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) remains uncertain. Methods We used data from OBLEX (ClinicalTrials.gov: NCT03714048), an international, prospective, observational study conducted..

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The role of acute normovolemic hemodilution and retrograde autologous priming in reducing intraoperative packed red blood cell transfusion needs in…

Abstract Background Acute normovolemic hemodilution (ANH) and retrograde autologous priming (RAP) are blood conservation techniques designed to reduce transfusion requirements. Purpose This study evaluated the impact of combining ANH and..

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Optimal 6-hour window for salvaged mediastinal blood retransfusion after cardiovascular surgery: an in vitro quality and safety analysis

Abstract Background - Postoperative hemorrhage is a significant complication of cardiovascular surgery. Although autologous cell salvage is safe and effective for preserving patients' blood, its use in the postoperative context remains..

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Risk–stratified outcomes of red blood cell transfusion in on–pump cardiac surgery

Abstract To the Editor: Red blood cell (RBC) transfusion is commonly performed during on-pump cardiac surgery; however, excessive use may lead to adverse clinical outcomes and medical resources wastage.[] The call..

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Intraoperative Cell Salvage in Oncologic Surgery: A Comprehensive Review

Abstract Intraoperative cell salvage (ICS) is a blood conservation technique utilized in major surgery, yet its application in oncologic procedures remains debated. Concerns persist about the theoretical risk of metastasis..

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Blood Transfusions are Associated With Prolonged Mechanical Ventilation Following Cardiac Surgery in Neonates

Abstract Background: To investigate the factors that influence blood transfusions after neonatal cardiac surgery and their association with prolonged mechanical ventilation (PMV) to provide a basis for optimizing blood transfusion..

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Efficacy and Safety of Desmopressin in Terms of Bleeding and Transfusion in Cardiac Surgery With Cardiopulmonary Bypass: A Systematic Review…

Abstract Bleeding and transfusion during cardiac surgery are major sources of complications. Surgery and cardiopulmonary bypass can induce coagulopathy, including platelet dysfunction. Desmopressin has been shown to reduce bleeding and..

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Evaluation of Intraoperative and Postoperative Blood Cell Salvage Use in Cardiac Surgery with Cardiopulmonary Bypass

Abstract Introduction:  Blood transfusion is associated with adverse clinical and surgical outcomes. Strategies like the Patient Blood Management program, which includes blood cell salvage, contribute to reducing the use of..

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Intraoperative Autologous Blood Transfusion in Aortic Surgery

Abstract Aortic surgeries are associated with intraoperative blood loss, often requiring allogeneic blood transfusion. Therefore, blood must be viewed as a scarce resource that carries risks and benefits. Many preoperative..

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Validation and optimization of a blood transfusion prediction model for low transfusion rate adult cardiac surgery

Abstract Introduction Blood transfusion is associated with adverse events and should be prevented. Preoperative identification of patients at risk is necessary and makes subsequent preventive intervention possible. Many risk models..

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Does Intraoperative Cell-Salvaged Autologous Blood Transfusion in Metastatic Spine Tumour Surgery Impact Clinical Outcomes: A Prospective Clinical Study With 4-year…

Abstract Study design Prospective Clinical Study. Objective Allogeneic blood transfusion (ABT) is the current standard of blood replenishment for metastatic spine tumour surgery (MSTS) despite known complications. Salvaged blood transfusion..

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Can clinical guidelines reduce variation in transfusion practice? A pre–post study of blood transfusions during cardiac surgery

Abstract Background and Objectives Previously published studies have consistently identified significant variation in red blood cell (RBC) transfusions during cardiac surgery. Clinical guidelines can be effective at improving the average..

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Development and validation of a nomogram for predicting perioperative transfusion in children undergoing cardiac surgery with CPB

Abstract Background Timely recognition of perioperative red blood cell transfusion (PRT) risk is crucial for developing personalized blood management strategies in pediatric patients. In this study, we sought to construct..

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What drives variability in postoperative cardiac surgery transfusion rates?

Abstract Objective Wide interhospital variation exists in cardiac surgical postoperative transfusion rates. We aimed to compare transfusion rates at 2 hospitals and identify the institutional practice factors, unrelated to patient..

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Significant reduction in blood product usage, same early outcomes: Blood conservation in infants undergoing open heart surgery

Abstract Objective To evaluate the effect of a blood conservation program on trends in use of donor blood products and early clinical outcomes in infants undergoing open heart surgery. Methods..

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It’s in your blood: The impact of age, sex, genetic factors and exposures on stored red blood cell metabolism

Abstract Transfusion of packed red blood cell (RBCs) saves millions of lives yearly worldwide, making packed RBCs the most commonly administered drug in hospitals after vaccines. However, not all blood..

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Evaluation of staged autologous blood transfusion during extracorporeal membrane oxygenation decannulation: A retrospective study

Abstract Background Clinical blood resources are scarce and autologous blood transfusion for extracorporeal membrane oxygenation (ECMO) withdrawal is less studied. Objectives To assess the use of staged autotransfusion during ECMO..

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Pitfalls of reasoning in hospital-based transfusion medicine

Abstract Introduction Hospital-based transfusion involves hundreds of daily medical decisions. Medical decision-making under uncertainty is susceptible to cognitive biases which can lead to systematic errors of reasoning and suboptimal patient..

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Impact of Blood Sampling Methods on Blood Loss and Transfusion After Pediatric Cardiac Surgery: An Observational Study

Abstract Objectives The aims of this study were to assess the impact of the closed-loop sampling method on  and the need for  in pediatric patients following cardiac surgery. Design Retrospective observational study...

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