Tags Archives: Autophagy

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Dysregulation of Autophagy in Circulating Platelets Is Associated with Platelet Dysfunction During Cardiopulmonary Bypass

Abstract Objectives To investigate whether cardiopulmonary bypass (CPB)-induced platelet dysfunction is associated with dysregulated autophagic flux in patients undergoing cardiac surgery. Design Prospective, single-center observational study. Setting A tertiary university..

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Cardiopulmonary Bypass Suppresses Forkhead Box O3 and Downstream Autophagy in the Diabetic Human Heart

Abstract Background Autophagy is an integral component of cellular  and metabolism. The exact mechanism of impaired autophagy in diabetes mellitus is unknown. Forkhead Box O3 (FOXO3α) is a key regulator of..

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