Tags Archives: Antifibrinolytics

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A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery

Abstract The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a “patient-focused, evidence-based and systematic approach for optimizing the..

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Prophylactic Use of Antifibrinolytics During Pediatric Cardiac Surgery With Cardiopulmonary Bypass on Postoperative Bleeding and Transfusion: A Systematic Review and…

Abstract Objectives:  To determine the effect of intraoperative antifibrinolytics, including tranexamic acid (TXA), aminocaproic acid (EACA), or aprotinin, on bleeding in children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Data..

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Blood Conservation in Cardiac Surgery: In Need of a Transfusion Revolution

Abstract Blood transfusion is the most common procedure in cardiac surgery. Increasing evidence exists that excess transfusions are harmful to patients. Transfusion reactions and complications, including infection, immune modulation, and..

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Aprotinin versus tranexamic acid in children undergoing cardiac surgery: an observational study

Abstract OBJECTIVES: The upcoming release of aprotinin in paediatric cardiac surgery prompted a re-evaluation of its use in comparison to tranexamic acid (TXA) focusing on their effect on exposure to..

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