Tags Archives: Antifibrinolytic agents

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Optimizing Tranexamic Acid Use in Adult Cardiac Surgery: From Rationale to Clinical Practice

Abstract  (TXA) has emerged as a cornerstone in blood conservation strategies for cardiac surgery. This comprehensive review synthesizes current evidence on TXA's efficacy, safety, and optimal use in various cardiac..

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A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objectives To examine the  (PK) and  of a tranexamic (TXA) regimen designed for cardiac surgery with  (CPB). Design A pilot study quantifying TXA concentrations,  markers, and a plasmin- generation (PG) assay. For comparison,..

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Topical and low-dose intravenous tranexamic acid in cyanotic cardiac surgery

Abstract Background Coagulopathy is a major problem in surgery for cyanotic congenital heart disease. Tranexamic acid has been used both topically and systemically and plays a vital role in pediatric..

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