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Managing Anticoagulation in Cardiopulmonary Bypass: Best Practices

Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, enabling complex procedures by temporarily taking over the heart and lung functions. However, one of the most critical aspects of..

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ECMO Management and Ventilator Settings: Optimizing Care for Critically Ill Patients

Introduction Extracorporeal Membrane Oxygenation (ECMO) is a critical intervention for patients with severe cardiac and respiratory failure. Although ECMO provides life-saving support, its management, particularly in conjunction with mechanical ventilation,..

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Review of the European Board of Cardiovascular Perfusion (EBCP) Guidelines: Implementation and Feasibility for Pakistani Perfusionists.

Introduction The European Board of Cardiovascular Perfusion (EBCP) establishes standardized guidelines to ensure quality and safety in perfusion practices across Europe. These guidelines provide a framework for clinical protocols, training,..

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Managing Serum Lactate During Cardiopulmonary Bypass

Serum lactate is a critical biomarker in cardiac surgery, offering insights into tissue oxygenation and metabolic status. Elevated lactate levels during cardiopulmonary bypass (CPB) can indicate inadequate perfusion, hypoxia, or..

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Alpha-Stat vs. pH-Stat Blood Gas Management During Cardiopulmonary Bypass

Introduction Blood gas management during cardiopulmonary bypass (CPB) is crucial for optimizing oxygen delivery and cerebral perfusion, especially in temperature-regulated surgeries such as deep hypothermic circulatory arrest (DHCA). Two primary..

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Common Mistakes in Perfusion and How to Avoid Them.

Perfusionists play a critical role in cardiac surgery and extracorporeal support, ensuring optimal oxygenation and circulation during procedures. However, given the complexity of the field, even experienced professionals can make..

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Parallel Venovenous Extracorporeal Membrane Oxygenation Circuits During Bridge-to-Lung Transplantation

Abstract Venovenous (VV) extracorporeal membrane oxygenation (ECMO) supports end-organ oxygen delivery in patients with refractory respiratory failure. Physical therapy (PT) while on ECMO provides conceptual benefits of strength and conditioning...

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Impact of Multistage Cannula on Recirculation in Various Venovenous Extracorporeal Membrane Oxygenation Cannulation Strategies

Abstract We aimed to compare recirculation of venovenous extracorporeal membrane oxygenation (V-V ECMO) administered with various cannula placements for femoro-femoral (F-F) and femoro-jugular (F-J) configurations in patients with respiratory failure...

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The first case of central Y–Y extra-corporeal membrane oxygenation system in a pediatric patient

Abstract The mechanical circulatory support (MCS) for pediatric patients with severe acute heart failure and poor pulmonary conditions is challenging. Herein, we report the first pediatric case of successfully treated..

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ECMO for the pregnant and peripartum patient: A practical review of indications, unique management considerations, and an approach framework

Abstract The use of extracorporeal membrane oxygenation (ECMO) to support the pregnant patient and fetus requires a complex decision-making process. Peripartum ECMO requires coordinated and informed decision-making between an interdisciplinary..

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Treatment time limit for successful weaning from veno‐arterial extracorporeal membrane oxygenation in cardiogenic shock

Abstract Aims Knowing the upper time limit for successful weaning from temporary mechanical circulatory support in cardiogenic shock will help with decision‐making regarding advanced heart failure (HF) therapy or considering..

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Extracorporeal lung perfusion and donation EVLPD in donation after circulatory death DCD

Extracorporeal lung perfusion and donation (EVLPD) in donation after circulatory death (DCD) patients is a groundbreaking advancement in organ transplantation, and Professor Sam Zeraatiannejaddavani, a world-renowned surgeon, has been at..

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Bilateral Lung Procurement for interstate Transfer

A to Z Steps of Bilateral Lung Procurement for interstate Transfer.   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of IUMS transplant..

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Organ Donation

Organ Donation after 60 minutes of Complete Cardiac Death in Patient with Previous Cardiac Surgery Mitral Valve Replacement.   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center..

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Impact of Cannulation Strategy and Extracorporeal Blood Flow on Recirculation During Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Introduction Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is increasingly used in the treatment of severe respiratory failure. Despite a significant increase in the worldwide use of extracorporeal lung assist..

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Implementation of Bundled Interventions to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery: A Quality Improvement Project

Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..

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Normothermic Crystalloid Polarizing Cardioplegia Improves Systolic and Diastolic Function in a Porcine Model of Cardiopulmonary Bypass

Abstract Background/Objectives: Previously, we showed that blood-based polarizing cardioplegia exerted beneficial cardioprotection during hypothermic ischemia; however, these positive effects of blood-based polarizing cardioplegia were reduced during normothermic ischemia compared to..

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The effects of changes in thrombocyte indices, on-on-pump time on prognosis in open heart surgery

Abstract Extracorporeal perfusion systems utilized in open-heart surgeries with cardiopulmonary bypass can affect multiple body systems. The primary adverse effects of Extracorporeal Perfusion Systems (EPS) on the hematological system include..

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Extracorporeal membrane oxygenation in pregnancy and the post-partum period: a systematic review and meta-analysis

Abstract Objective There is an increase in the application data of Extracorporeal Membrane Oxygenation (ECMO) in perinatal women, particularly since the outbreak of coronavirus disease 2019. Therefore, we reviewed publications..

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Developing active learning activities for didactic perfusion courses

Abstract Background In the world of academia, traditional lecturing has been the most common pedagogical approach for centuries. However, it can create an environment for students to be passive learners..

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Congenital cardiac surgical simulation: bridging global workforce gaps and optimizing outcomes

Abstract Reaching competency in congenital heart surgery (CHS) requires lengthy and rigorous training. Due to patient safety, time limitations, and procedural complexity, the intraoperative setting is not ideal for technical..

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Advances in understanding the effects of cardiopulmonary bypass on gut microbiota during cardiac surgery

Abstract Cardiopulmonary bypass (CPB) is an indispensable technique in cardiac surgery; however, its impact on gut microbiota and metabolites remains insufficiently studied. CPB may disrupt the intestinal mucosal barrier, altering..

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Effects of noradrenaline and phenylephrine on cerebral oxygen saturation during cardiopulmonary bypass in cardiac surgery

Abstract Cardiopulmonary bypass (CPB) in cardiac surgery is associated with a high risk of postoperative neurological complications. Perioperative use of vasopressors is common to counteract arterial hypotension in this setting...

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The influence of cardiopulmonary bypass residual volume processing technique on blood management in cardiac surgical patients

Abstract Background: Post-cardiopulmonary bypass (CPB) blood processing is an important component of blood management during cardiac surgery.    Purpose: The purpose of this study is to evaluate several methods of processing post-CPB..

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Acute aortic dissection during minimally invasive cardiac surgery: a case report

Abstract Background Management of acute aortic dissection (AAD) caused by retrograde perfusion through the femoral artery during minimally invasive cardiac surgery (MICS) remains controversial. We present a case of AAD..

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Direct Axillary Artery Cannulation as Standard Perfusion Strategy in Minimally Invasive Coronary Artery Bypass Grafting

Abstract Objective: Cardiopulmonary bypass (CPB) via the right axillary artery (RAA) has become an alternative perfusion strategy, especially in complex aortic procedures. This study delineates our technique and outcome with..

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Anti-platelet Factor 4 Antibody-Mediated Disorders: An Updated Narrative Review

Abstract Anti-platelet factor 4 (PF4) antibody-mediated disorders are a heterogeneous group of diseases characterized by the presence of highly pathogenic immunoglobulins G directed against PF4 and/or PF4/heparin complexes. These antibodies..

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Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac…

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for adults with cardiac arrest (CA) refractory to Advanced Cardiovascular Life Support (ACLS). Concerns exist that adding ECPR could worsen health..

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Preoperative vascular dysfunction is associated with acute kidney injury after cardiac surgery

Abstract Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) results in poor prognosis. Several risk factors for CSA-AKI have been reported, including preoperative creatinine level, cardiopulmonary bypass time, and perioperative blood pressure..

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ECMO in the Cardiac Catheterization Lab—Patient Selection Is Key

Abstract The use of extracorporeal membrane oxygenation (ECMO) has emerged as a rescue intervention for hemodynamically unstable patients and prophylactic intraprocedural hemodynamic support in the cardiac catheterization laboratory. The prompt..

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