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Basic Goals of Myocardial Protection During Cardiopulmonary Bypass (CPB)

Introduction Cardiopulmonary bypass (CPB) is essential for modern cardiac surgery, allowing complex repairs and reconstructions by diverting blood away from the heart and lungs. However, during this process, the heart's..

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Inflammatory Responses During Cardiopulmonary Bypass: Mechanisms, Mediators, and Management Strategies

Abstract: Cardiopulmonary bypass (CPB) induces a multifactorial systemic inflammatory response that significantly contributes to postoperative complications such as acute lung injury, renal dysfunction, and increased morbidity. This response is initiated..

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Perfusion Physiology: The Interplay of Flow, Pressure, Hematocrit, and Oxygen Delivery.

Introduction Cardiopulmonary bypass (CPB) has revolutionized cardiac surgery by temporarily taking over the function of the heart and lungs during complex procedures. Central to this technique is the management of..

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Optimizing Filtration in Cardiopulmonary Bypass: A Comprehensive Overview

Introduction Cardiopulmonary bypass (CPB) plays a pivotal role in modern cardiac surgery by temporarily assuming the functions of the heart and lungs during complex procedures. However, despite its life-saving capabilities,..

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Aseptic Techniques in the Setup of Cardiopulmonary Bypass: Ensuring Safety in Cardiac Surgery

Introduction: Cardiac surgery is among the most delicate and high-risk procedures in modern medicine, and the use of cardiopulmonary bypass (CPB) is central to its success. In this complex setting,..

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Priming Techniques in Cardiopulmonary Bypass: An Overview.

Introduction Cardiopulmonary bypass (CPB) is a cornerstone of modern cardiac surgery, facilitating complex intracardiac procedures by temporarily assuming the function of the heart and lungs. One of the most critical..

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Cerebral Hemodynamic Monitoring via Transcranial Doppler Ultrasound and Near-Infrared Spectroscopy for Risk-Stratified Pediatric Cardiac Surgery Patients

Abstract Background The objective of this study was to evaluate mean cerebral blood flow velocity, gaseous microemboli (GME) counts, regional cerebral oxygen saturation (rSO2), and clinical outcomes using multimodality neuromonitoring..

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Sepsis-Extracorporeal Membrane Oxygenation Score in Patients Receiving Extracorporeal Membrane Oxygenation Support for Sepsis

Abstract Predictive scoring systems for adult patients receiving extracorporeal membrane oxygenation (ECMO) support for sepsis have not been yet reported. Based on the Chinese Society of ExtraCorporeal Life Support (CSECLS)..

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Effect of extracorporeal circulation on structure of main components of animal plasma – ATR-IR and 2D-COS studies: Part I

Abstract Every year, more and more adults and children with severe cardiac and/or respiratory failure require connection to extracorporeal circulation (ECC). Despite a life-saving role in emergency settings, the use..

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Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry

Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..

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Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV

Abstract Objective To establish a nomogram for predicting the occurrence of postoperative delirium (POD) in patients undergoing cardiac surgery. Materials and methods Data from 5379 patients were retrieved from the..

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Sex-related differences in systemic inflammatory response and outcomes after cardiac surgery and cardiopulmonary bypass

Abstract OBJECTIVES Differences in inflammatory responses between men and women may contribute to sex disparities in cardiac surgery outcomes. We investigated how sex differences influence systemic inflammatory response syndrome (SIRS)..

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Practical Considerations for Extracorporeal Membrane Oxygenation Use During Orthotopic Liver Transplantation

Abstract Patients undergoing liver transplantation infrequently require extracorporeal membrane oxygenation (ECMO) support. However, when ECMO is required in the peritransplant period, several key considerations are required to maximize the efficacy..

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Vasoplegia in Cardiac Surgery: A Systematic Review and Meta-analysis of Current Definitions and Their Influence on Clinical Outcomes

Abstract Objectives To identify differences in the reported vasoplegia incidence, intensive care unit (ICU) length of stay (LOS), and 30-day mortality rates as influenced by different vasoplegia definitions used in..

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Fluid management in adult patients undergoing venoarterial extracorporeal membrane oxygenation: A scoping review

Abstract Background The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a cardiocirculatory support has tremendously increased in critically ill patients. Although fluid therapy is an essential component of the..

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Summary of the best evidence for the management of kinesiophobia in patients after cardiac surgery

Abstract Background This study aimed to systematically search for relevant evidence on the management of kinesiophobia in patients after cardiac surgery both home and abroad. The evidence was evaluated and..

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Carboxyhemoglobin and Methemoglobin as Biomarkers of Hemolysis and Mortality in Acute Respiratory Distress Syndrome Treated by Veno-Venous Extracorporeal Membrane Oxygenation

Abstract BACKGROUND:  Critically ill patients who receive circulatory or respiratory assist using extracorporeal membrane oxygenation (ECMO) may develop hemolysis, which can complicate the delivery of supportive care and be a..

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Aortic Regurgitation - Regurgitacion Aortica

      The echo lady; Lorena De Vanna, is a cardiac and respiratory physiologist graduated from the Central University of Venezuela. She currently holds British Society of Echocardiography accreditation..

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Preparing lung transplant with Ex Vivo Lung Perfusion Device

Preparing the Child lung for transplant into the Adult patient with usage of EVLPD or Ex Vivo Lung Perfusion Device a practical application which every Perfusionist should be familiar with...

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Totally Robotic Left Atrial Myxoma Removal

Totally Robotic Left Atrial Myxoma Removal with Ant.Lat Thoracotomy of the right chest limited accress femoral and Int.Jugular Cannula inserted for total inflow occlusion technique as well as cardio with..

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Lung procurement with ex vivo lung perfusion

A complete advance series of lung procurement and usage of ex vivo lung perfusion technologies or device either in the presence of pulmonary thromboembolism.   Dr.Sam Zeraatian Nejad Davani, CEO..

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Circular Shunt: A Loop Not to Be Ignored

Abstract A circular shunt, initially described by Shone et al. in 1962, refers to abnormal blood recirculation through complete intracardiac or intra- and extracardiac communications, bypassing the capillary beds. This..

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Left Ventricular Unloading Using Intra-aortic Entrainment Pumping Before Reperfusion Reduces Post-AMI Infarct Size

Abstract Background Anterior myocardial infarction standard of care prioritizes swift coronary reperfusion. Recent studies show left ventricular (LV) unloading with transvalvular axial flow pumps for 30 minutes before reperfusion (vs..

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Total bilirubin as a marker for hemolysis and outcome in patients with severe ARDS treated with veno-venous ECMO

Abstract Background Hemolysis is a common complication in critically ill patients with sepsis, acute respiratory distress syndrome (ARDS) or therapy with extracorporeal membrane oxygenation (ECMO). Heme degradation product bilirubin might..

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The impact of thyroid function on surgical prognosis in patients undergoing cardiac and major vascular surgeries

Abstract Objective This study aims to elucidate the relationship between thyroid function and surgical prognosis in patients undergoing cardiac and major vascular surgeries. Methods A retrospective cohort study was conducted..

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Prothrombotic Microvesicle Generation in Pediatric Cardiopulmonary Bypass: A Pilot Observational Study

Abstract Over 10% of children develop thrombosis after cardiac surgery for congenital heart disease. Children with a single ventricle physiology have the highest risk of thrombosis associated with increased length..

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Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

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Assay of cardiopulmonary bypass system for porcine alveolar macrophages removing GFP-E. coli from erythrocyte surfaces

Abstract While it is established that complement receptor molecules on the surface of erythrocytes are crucial for the clearance of immune complexes in the body, the molecular mechanisms underlying the..

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