Abstract Patients undergoing cardiopulmonary bypass (CPB) often experience neurological complications, but the neurobiological mechanisms remain unclear. This study combined resting-state fMRI, structural MRI, and cognitive testing to examine brain changes..
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Abstract Objective Acute kidney injury (AKI) affects approximately 30% of patients undergoing cardiac surgery with conventional non-pulsatile cardiopulmonary bypass (CPB). Pulsatile flow has long been proposed for mitigating this complication...
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Abstract OBJECTIVES Acute kidney injury (AKI) is a common consequence of surgical repair of the thoraco-abdominal aorta (TAA). Perfusion techniques aim to facilitate renal protection through oxygenation or hypothermia. This..
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Abstract Background Gastrointestinal complications (GICs) following cardiac surgery with cardiopulmonary bypass (CPB) significantly impact postoperative recovery and clinical outcomes. Methods This single-center, retrospective cohort study evaluated the incidence, risk factors,..
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Abstract Background: The objective of this study was to describe thrombin generation in children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Change in the endogenous thrombin potential (ETP) across three..
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Abstract Assessment of cerebral autoregulation is challenging under different hemodynamic conditions during cardiac surgery and must be rapidly calculated in order to optimize mean arterial pressure (MAP). Whether systemic flow..
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Abstract Evaluating the impact of cardiac surgery on humoral and cellular immunity in pediatric congenital heart disease patients with prior Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection or vaccination..
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Abstract Purpose Cardiac surgery associated acute kidney injury (CSA-AKI) is a frequent and severe complication. Goal Directed Perfusion (GDP) during cardiopulmonary bypass (CPB) has been developed to reduce post-operative complications,..
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Abstract Objectives Intraoperative cell salvage (ICS) is broadly used in high-risk surgical procedures to facilitate rapid autologous red blood cell transfusion, minimizing the need for allogeneic blood and its associated..
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Abstract Acute Kidney Injury (AKI) is a common complication after cardiac surgery affecting up to 40% leading to increased morbidity and mortality. To date, there is no specific treatment for..
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Abstract BACKGROUND Exposure to supra-physiologic levels of oxygen has been associated with end-organ damage and worse outcomes across multiple populations related to oxidative stress and inflammation. There is limited evidence..
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Abstract Licensure in medicine originated in London when a small group of physicians led by the scholar Thomas Linacre petitioned King Henry VIII to establish a college of physicians on..
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Abstract Background ECPR patients who receive guideline-compliant CPR will have improved survival to hospital discharge (SHD) compared to patients who do not receive guideline-compliant CPR, regardless of CPR duration. Methods..
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Abstract Heart failure remains a leading cause of morbidity and mortality globally, particularly among individuals with advanced forms of the disease. This study introduces a groundbreaking hydromagnetic artificial heart..
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Abstract We report the case of a 54-year-old man with right-lung pneumonia and contralateral pulmonary embolism (PE) conditioning severe refractory hypoxemia requiring veno-venous extracorporeal membrane oxygenation. Electrical impedance tomography (EIT)..
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Abstract This study conducts an in-vitro experiment using a mock circulation system that mimics human circulation to assess the veno-arterial extracorporeal membrane oxygenation (ECMO) system. This study aims to compare the hemodynamic..
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Abstract Preterm birth remains the leading cause of mortality among neonates. Despite improvements in neonatal intensive care over the years, current treatments for lung and kidney failure are highly invasive,..
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Abstract Although venovenous (VV) extracorporeal membrane oxygenation (ECMO) is a life-saving intervention for trauma patients with severe respiratory failure, its mortality rate is 27%, and optimal metabolic markers for its..
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Introduction Profound hypotension and end-organ hypoperfusion is most often a consequence of inadequate systemic blood flow from primary cardiac failure (cardiogenic shock) or hemorrhage (hemorrhagic shock). However, profound hypotension may..
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Abstract Extracorporeal membrane oxygenation (ECMO) is the most important support for patients with severe cardiopulmonary failure. As the key component, the oxygenation membrane has suffered the risk of blood coagulation..
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Abstract The use of extracorporeal membrane oxygenation (ECMO) in the paediatric population has increased over time, with the ability to rescue pulmonary and cardiovascular deterioration. ECMO can be utilised by..
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Abstract Objective To describe the occurrence of cerebral desaturation (≥10% decrease or <50% in regional cerebral oxygen saturation [rSO₂]), deep anesthetic states (processed electroencephalography patient state index [PSI] <25), and..
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Abstract Objective: We aimed to characterize the impact of body mass index (BMI) on stroke in patients receiving extracorporeal cardiopulmonary resuscitation (ECPR). Methods: We queried the Extracorporeal Life Support Organization registry..
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Abstract Background The effect of Friday the 13th and Full Moons on cardiac transplantation is unknown. We investigated the impact of these superstitious events on recipient and donor qualities, complications,..
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Abstract Background Antithrombin signalling may exert an anti-inflammatory effect; therefore we hypothesised that individuals with inherited antithrombin deficiency (ATD) may have an altered inflammatory state. Aims To assess the inflammatory..
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Abstract The autonomic nervous system is critical for regulating cardiovascular physiology. The neurocardiac axis encompasses multiple levels of control, including the motor circuits of the sympathetic and parasympathetic nervous systems,..
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Abstract The use of extracorporeal membrane oxygenation has been increasing over time, in part due to the COVID-19 pandemic. Whilst lifesaving, complications that must be managed are also associated with..
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Abstract Aims This study aims to identify distinct clusters of patients undergoing coronary artery bypass grafting (CABG) based on demographic, clinical, and autonomic function characteristics and to validate these clusters...
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Abstract Background Outcomes in cardiac surgery are influenced by surgical priority, with higher mortality in emergency cases. Whether this applies to postcardiotomy venoarterial (VA) extracorporeal membrane oxygenation (ECMO) remains unknown...
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Abstract Acute poisoning may lead to life-threatening conditions that require advanced life support, such as extracorporeal membrane oxygenation (ECMO). Data about the use of ECMO in intoxications and overdose are..
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