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A rule-based clinical decision support system for detection of acute kidney injury after pediatric cardiac surgery

Abstract Background Acute kidney injury (AKI) is common in children with congenital heart disease following open-heart surgery with cardiopulmonary bypass (CPB). Early AKI detection in critically ill children requires clinician..

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Veno-venous extracorporeal membrane oxygenation exacerbates lung ischaemia–reperfusion injury in a rat model

Abstract OBJECTIVES Although lung transplantation has experienced great development in the past decades, the survival rate remains low, and lung ischaemia–reperfusion injury during transplantation is a major cause of primary..

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Mechanical circulatory support in cardiogenic shock: translating trial evidence into real-world practice

Abstract While iterative developments have improved outcomes of patients with myocardial infarction, mortality in patients with acute myocardial infarction cardiogenic shock (AMI-CS) remains stubbornly high. Several promising treatments have ultimately..

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Patient Characteristics and Extracorporeal Membrane Oxygenation Outcomes at Nelson Mandela Children’s Hospital: A South African Experience

Abstract This study aimed to describe patient characteristics, mortality, and morbidity outcomes in children at a South African extracorporeal membrane oxygenation (ECMO) center. Fifty-seven patients required ECMO from 2018 to..

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Microplastic in perfusion: the hidden risk and how to address it

Abstract The paper published in this issue of the ICVTS by Green and colleagues [] from the University of Hull in the UK addresses an often underestimated yet increasingly recognized issue in..

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Impact of frailty on outcomes after cardiac surgery

Abstract Objective The study objective was to evaluate whether increasing , as measured by the Clinical Frailty Scale, was associated with an increased risk of hospital mortality for patients undergoing cardiac..

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Protocol for the development of NHMRC-endorsed guidelines for extracorporeal membrane oxygenation using GRADE methodology

Abstract Introduction The last 15 years have seen a rapid expansion in the use of extracorporeal life support. ECMO has evolved from a rescue treatment available in a few expert..

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No benefit of adding mannitol to cardiopulmonary bypass priming solution assessing cystatin C. A randomized clinical trial

Abstract Introduction There is no recommendation regarding the optimal prime solution for the cardiopulmonary bypass circuit in adult cardiac surgery. Despite the lack of scientific evidence, mannitol has frequently been..

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Troubleshooting for the Empowered ECMO Nurse

Abstract An Introduction to ECMO Troubleshooting Like other ECMO nurses, I will never forget the first time I had to troubleshoot an  circuit. My patient had returned to the intensive care..

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Association between venous to arterial carbon dioxide tension gap and clinical outcome in cardiac surgery patients: A systematic review and…

Abstract Background Cardiac surgery is associated with increased risk of major adverse outcomes. Venous to arterial carbon dioxide tension gap (Pv-aCO2 gap) showed significant prognostic value of non-cardiac surgery, while their..

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Comparison of outcomes between axillary and femoral artery cannulation for type A aortic dissection surgery

Abstract Objective To compare the application and outcomes of femoral versus axillary arterial cannulation in adult patients undergoing surgery for type A aortic dissection. Methods We conducted a retrospective review..

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Postoperative hemoglobin changes following ultrafiltration in cardiac patients

Abstract Introduction This retrospective study investigated the relationship between differing thresholds of Conventional Ultrafiltration (CUF) and postoperative hemoglobin (HGB) in cardiac surgery cases involving cardiopulmonary bypass. Methods The study utilized..

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Utilization and outcomes of nonintubated extracorporeal membrane oxygenation as a bridge to lung transplant

Abstract Background Nonintubated extracorporeal membrane oxygenation (ECMO) has been increasingly utilized for patients with severe respiratory failure. Since data on its use as a bridge to lung transplant remain limited,..

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Clinical impact of changes in plasma osmolarity and pump time during cardiopulmonary bypass use

Abstract Aims To evaluate the roles of intraoperative changes in plasma osmolarity and pump time as predictor factors on postoperative hemodynamic instability and mid-term clinical outcomes, in adults undergoing cardiovascular..

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Evaluation of Integrated Arterial Filter Oxygenator vs. External Arterial Filters on Clinical Outcomes and Neurocognitive Function in Pediatric Cardiac Surgery:…

Abstract Background and Aims Innovative advancements in cardiopulmonary bypass (CPB) configurations, such as surface coating, blood filtration, and miniaturization, aim to reduce gaseous microemboli (GME) that contribute to embolic organ..

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Comparison of Short-Term Outcomes of Extubation in the Operating Room and Extubating in the Intensive Care Unit After Cardiac Surgery:…

Abstract Objectives: This study aimed to compare short-term outcomes in patients extubated in the operating room (ORE) vs those extubated in the intensive care unit (ICUE) following cardiac surgery.    Methods: A..

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High-risk pulmonary embolism: the significance and perspectives of pulmonary reperfusion

Abstract Rapid hemodynamic stabilization and restoration of pulmonary perfusion are the cornerstones of treatment for high-risk pulmonary embolism (PE). While all current guidelines recommend systemic thrombolysis (SYS) as the first-line..

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Routine Use of an On-Table Extubation Protocol in Pediatric Cardiac Surgery—Our Experience With Life in the Fast Lane

Abstract Background We undertook this study to evaluate the efficacy of an on-table extubation protocol and to assess the magnitude of benefits when implemented as a routine practice in a..

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Extracorporeal Membrane Oxygenation as a Bridge to Recovery in Children With Severe Necrotizing Pneumonia: Case Report

Abstract Necrotizing pneumonia is a severe complication of bacterial or viral pneumonia that can lead to refractory respiratory failure in children. Extracorporeal membrane oxygenation (ECMO) has emerged as a vital..

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Extracorporeal Membrane Oxygenation in Pulmonary Embolism: Current Evidence and Evolving Data

Abstract PULMONARY EMBOLISM (PE) remains a significant healthcare challenge, ranking as the third leading cause of mortality worldwide, following coronary artery disease and stroke. In the United States, mortality rates among..

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Outcomes after hospital discharge in children requiring post-cardiotomy extracorporeal membrane oxygenation: A binational retrospective cohort study

Abstract Objectives To describe longer-term survival and morbidity outcomes after hospital discharge in a binational cohort of children who required extracorporeal membrane oxygenation after cardiac surgery. Methods This was a..

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Clinical assessment of cannula performance during adult minimally invasive valve surgery using predictive mathematical models

Abstract OBJECTIVES Peripheral cannula selection in minimally invasive cardiac surgery (MICS) is crucial, as venous drainage limitations during cardiopulmonary bypass (CPB) can impair end-organ perfusion and overall outcomes. This study..

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Bloodless lung transplantation: Comparison between 2 central venoarterial extracorporeal membrane oxygenation anticoagulation strategies and their impact on lung transplant outcomes

Abstract Objective To report differences between 2 anticoagulation protocols during venoarterial extracorporeal membrane oxygenation (VA-ECMO) intraoperative support and their effects on outcomes after lung transplantation. Methods We performed a retrospective..

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Saline-based modified del Nido cardioplegia versus multidose St. Thomas cardioplegia in canine mitral valve repair: A randomized controlled trial

Abstract Objective To compare the utility of a saline-based modified del Nido (mDN) cardioplegia solution with a conventional institutional technique (multidose St. Thomas blood cardioplegia) for mitral valve repair (MVR)..

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Exploring the role of inflammation and proinflammatory proteins in coagulopathy during venovenous extracorporeal membrane oxygenation

Abstract Background Coagulopathy frequently complicates venovenous extracorporeal membrane oxygenation (VV ECMO) procedures, yet its underlying mechanism remains elusive. This retrospective study aimed to identify factors contributing to coagulopathy during VV..

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A heart full of nails: complex management of multiple nail gun cardiac injuries

Abstract A 54-year-old male presented after a suicide attempt, suffering severe cardiac and extracardiac injuries from firing a nail gun into both temples () and his chest. Imaging showed six..

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The use of checklists in the intensive care unit: a scoping review

Abstract Background Despite the extensive volume of research published on checklists in the intensive care unit (ICU), no review has been published on the broader role of checklists within the..

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Vasoplegic syndrome in cardiac surgery: bridging therapeutic gaps with best practices and future research

Abstract Vasoplegic syndrome (VS) is a common and potentially life-threatening complication of cardiac surgery with cardiopulmonary bypass (CPB). It presents a significant haemodynamic challenge that is often difficult to manage..

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Analysis of the feasibility of a low-anticoagulation strategy in patients undergoing post-cardiotomy extracorporeal membrane oxygenation: a retrospective cohort study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is increasingly used in patients after cardiac surgery; however, anticoagulation management has consistently been challenging. This study aimed to explore the feasibility of a..

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Impact of routine extracorporeal cardiopulmonary resuscitation service on the availability of donor organs

Abstract Background In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors...

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