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Incidence, kinetics, and clinical impact of thrombocytopenia in venovenous ECMO: insights from the multicenter observational PROTECMO study

Abstract Background Thrombocytopenia is a recognized risk factor for bleeding during extracorporeal membrane oxygenation (ECMO). This study determines the incidence, risk factors, and clinical relevance of thrombocytopenia and platelet transfusions..

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Sleep protects the heart after myocardial infarction through a neuro-immune axis: time to implement healthy sleep for cardiovascular prevention?

Abstract Sleep is essential for human health and represents an active state of unconsciousness that plays a critical role in restoring brain and body functions, as well as regulating the..

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The effect of cardiopulmonary bypass on hemorheology: Evaluation of clinical outcomes

Abstract Background During cardiopulmonary bypass (CPB), which is frequently utilized in open-heart surgery, the maintenance of circulation in a non-physiological environment may lead to alterations in the properties of circulating..

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Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries

Abstract Background The global prevalence of congenital heart disease (CHD) is increasing. Research on patient-reported outcomes (PROs) predominantly originates from high-income countries, resulting in an incomplete understanding of the true global..

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Hydroxocobalamin for vasoplegia in cardiac surgery: a retrospective cohort analysis

Abstract Background Vasoplegia during cardiac surgery is common and associated with perioperative mortality. Hydroxocobalamin is a catecholamine-sparing approach for treating vasoplegia. However, there is currently limited evidence to inform its..

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Contemporary use and safety of prepartum autologous blood donation: A retrospective cohort study in Quebec, Canada

Abstract Background Autologous blood donation (ABD) can be indicated in pregnant individuals with rare blood groups. Yet, unlike hospitals, some blood establishments are reluctant to collect ABDs in this population...

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2024 Guidelines on Patient Blood Management for Adult Cardiac Surgery Under Cardiopulmonary Bypass in China

Abstract The Working Group on Cardiopulmonary Bypass and Extracorporeal Life Support of China National Center for Cardiovascular Quality Improvement presents evidence-based guidelines on patient blood management for adult cardiac surgery..

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Storage duration of packed red blood cells transfused during veno-venous extracorporealmembrane oxygenation is associatedwith elevated pulmonary artery pressureand lung injury…

Abstract Background Veno‑venous extracorporeal membrane oxygenation (VV‑ECMO) is associated with a high transfusion burden. While trials have concluded that red blood cell (RBC) storage does not impact patient morbidity and..

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Is the use of ECPR for OHCA ready for broad implementation?

Abstract The use of Extracorporeal Cardiopulmonary Resuscitation (ECPR) in cases of cardiac arrest is increasing, as addressed in the number of cases in the Extracorporeal Life Support Organization (ELSO) dashboard. Of..

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Crescent jugular dual-lumen catheter for adult veno-venous extracorporeal membrane oxygenation in China: Multicenter initial experience

Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a life support technique used for patients with life-threatening respiratory failure. It effectively addresses arterial hypoxemia without overstretching the injured lungs. Traditional..

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Pharmacological Research Agenda on Adult Extracorporeal Membrane Oxygenation Using the Delphi Method: A Position Article of the Extracorporeal Membrane Oxygenation…

Abstract Objectives:  Extracorporeal membrane oxygenation (ECMO) is a critical intervention for patients with severe cardiac or respiratory failure. However, pharmacological management for ECMO-supported patients presents unique challenges due to alterations..

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Optimal ECLS Support in Mixed Cardiogenic and Septic Shock: An ELSO Registry Analysis

Abstract Background Mixed cardiogenic and septic shock has been shown to have a higher mortality than cardiogenic shock alone and presents a unique hemodynamic phenotype. Objectives This study aimed to..

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Patients Post Cardiac Surgery Requiring Venoarterial Extracorporeal Membrane Oxygenation: Outcomes From an Intensivist-Led Extracorporeal Membrane Oxygenation Program

Abstract Post cardiac surgery shock (PCS) is a life-threatening condition that may require the use of mechanical circulatory support. Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is increasingly used to treat..

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Outcomes of Patients Requiring VA-ECMO for Cardiogenic Shock and Evaluation of Programmatic Changes

Abstract Objectives To describe outcomes in patients who received venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock and to evaluate outcomes following programmatic changes. Design A retrospective cohort study. Setting..

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Extracorporeal Support Vascular Access: 3D Printing Custom Cannulas

Abstract Extracorporeal life support (ECLS) requires specialized cannulas for vascular access that are dependent on each patient’s needs, size, and unique vascular anatomy. There are currently no commercially available drainage..

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Flow of Data, Not Blood Flow, Is the Key to Unraveling ECMO Support in Mixed Shock

Abstract Mixed shock has been identified by the Shock Academic Research Consortium (SHARC) as a “high-risk, understudied population”. It develops in around one-quarter of patients with cardiogenic shock and has a higher..

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Trends and institutional patterns of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest in Korea: a nationwide analysis, 2016–2023

Abstract Background While the clinical effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) has gained increasing attention, its real-world utilization, patient selection, and system-level implementation remain incompletely..

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Optimizing Extracorporeal Cardiopulmonary Resuscitation Delivery for Out-of-Hospital Cardiac Arrest: A Monte Carlo Simulation Study

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) can improve outcomes in refractory out-of-hospital cardiac arrest (OHCA), but access is limited by geographic and system constraints. We aimed to compare the potential..

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The combined impact of AI and VR on interdisciplinary learning and patient safety in healthcare education: a narrative review

Abstract Introduction The increasing integration of Artificial Intelligence (AI) and Virtual Reality (VR) in healthcare education offers innovative ways to enhance collaborative learning and improve patient safety. This narrative review..

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Modern overhaul of the Pre-CPB checklist: Leveraging live data capture to replace yes/no checklist design

Abstract Introduction Standard “yes/no”' checklists fail to meet their purported goals of enhancing patient safety because they enable inattentive completion and complacency. The mere presence of a check mark is..

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Current intraoperative mechanical circulatory support strategies for bilateral lung transplantation surgery

Abstract Objective To discuss technical strategies and considerations to facilitate intraoperative extracorporeal membrane oxygenation (ECMO) management during lung transplantation. Methods We review our institutional approach to the management of intraoperative..

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Impact of acute kidney injury and dysnatremia on length of stay in infants after cardiac surgery

Abstract Background Acute kidney injury (AKI) and dysnatremia following pediatric cardiac surgery are common conditions associated with worse outcomes. While the multifactorial etiology of AKI is well-known, the role of..

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Modified ultrafiltration warming technology in pediatric congenital heart disease surgery: A case‒control study

Abstract Background To evaluate the effect and safety of modified ultrafiltration warming technology during pediatric congenital heart disease (CHD) surgery. Methods A retrospective analysis included 68 children (<1 year) who..

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Minimally Invasive vs Conventional Coronary Bypass Surgery for Multivessel Coronary Disease

Abstract Background Despite sternum sparing and without cardiopulmonary bypass, the actual value of minimally invasive coronary surgery (MICS) is still debatable. This study aimed to compare the completeness of revascularization..

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Venovenous extracorporeal membrane oxygenation with mechanical chest compression for cardiopulmonary resuscitation: A porcine model study

Abstract Objective To evaluate the effectiveness of venovenous (VV) extracorporeal membrane oxygenation (ECMO) using a dual-lumen cannula coupled with continuous mechanical chest compressions (cMCC) for cardiopulmonary resuscitation and compare it..

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Hypotension During Cardioplegia Administration: Does the Route of Delivery Matter?

Abstract Objective To determine if the route of administration of whole blood cardioplegia (cardioplegia) is significantly associated with the frequency of profound transient hypotension (intermittent “vasoplegia”) often observed during cardioplegia..

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A Continuous, Real-Time Coagulation State Monitor for ECMO Patients

Abstract For patients undergoing extracorporeal membrane oxygenation (ECMO), clot formation is a critical complication requiring high-risk circuit changes. Blood tests used to assess clotting risk may be drawn only four..

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Red blood cell transfusion practices in extracorporeal membrane oxygenation: A single-center study

Abstract Objectives Evaluating blood transfusion practices and their impact on morbidity and mortality across extracorporeal membrane oxygenation (ECMO) configurations. Background As ECMO becomes increasingly utilised in critical care, the ideal..

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Arterial Cannula Size Selection for Percutaneous Femoral Venoarterial Extracorporeal Membrane Oxygenation in Children and Young Adults: Solving a Goldilocks Paradox?

Abstract The correct arterial cannula size for percutaneous femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) cannulation is imperative for adequate circulatory support. We aimed to describe the relationship between cannula size,..

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The Relationship Between the Type of Microorganisms Isolated in Cultures and Outcomes in Children on Extracorporeal Membrane Oxygenation Support Following…

Abstract Objetives Extracorporeal membrane oxygenation (ECMO) after surgery for congenital heart disease (CHD) provides hemodynamic support to patients when their myocardial function is temporarily affected. Postoperative infections in children with..

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