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Heterogeneity of Treatment Effect for Intra-Aortic Balloon Pump Use Across Lactate Trajectories in Cardiogenic Shock Patients Supported by VA-ECMO: An…

Abstract This study aimed to investigate the heterogeneity of treatment effect for intra-aortic balloon pump (IABP) across various lactate trajectories in patients with acute myocardial infarction-related cardiogenic shock (AMICS) supported..

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Ischemic and hemorrhagic stroke in pediatric patients after extracorporeal membrane oxygenation decannulation: a systematic review

Abstract OBJECTIVE Extracorporeal membrane oxygenation (ECMO) is a vital support for pediatric patients with severe cardiac or pulmonary failure. However, post-decannulation complications, particularly involving carotid artery ligation (CAL) or carotid..

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The Association Between Early Postoperative Temperature Trajectories and Severe Acute Kidney Injury After Valvular Heart Surgery: A Retrospective Cohort Study

Abstract Background/Objectives: Postoperative body temperature abnormalities are common yet underrecognized, and their association with acute kidney injury (AKI) remains unclear. In this study, we aimed to identify early postoperative temperature..

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Radical Pericardiectomy and Use of Cardiopulmonary Bypass for Constrictive Pericarditis

Abstract Background Pericardiectomy is a definitive treatment for constrictive pericarditis. However, the extent of resection and cardiopulmonary bypass (CPB) use remain debated. We therefore compared hemodynamic changes, complications, long-term survival,..

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Distal Limb Perfusion in Extracorporeal Membrane Oxygenation

Abstract Limb ischemia is the most common vascular complication in patients receiving femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO) and is associated with an increased risk of mortality., To improve blood flow..

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Determining an optimal central cannulation strategy for ambulatory veno-venous extracorporeal life support

Abstract Background Chronic obstructive pulmonary disease (COPD) is the most prevalent chronic end stage lung disease. There are few long-term treatment options for end stage COPD due to donor lung..

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Nutrition support practices in cardiothoracic surgery patients with gastrointestinal complications: An observational study

Abstract Introduction Gastrointestinal (GI) complications following cardiac surgery involving cardiopulmonary bypass are rare but life threatening. Despite GI complications having implications for nutrition delivery, nutrition support practices in this population..

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Temporal evolution of arterial pulse pressure trajectories as early predictor of weaning success in venoarterial extracorporeal membrane oxygenation

Abstract Introduction: Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) remains a major challenge because reliable indicators of cardiac recovery are lacking. Arterial pulse pressure (PP), a simple and continuously measured..

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Weaning From Mechanical Ventilation in Cardiac Surgery Patients: Current Strategies, Monitoring Innovations, and Future Perspectives

Abstract Weaning from mechanical ventilation after cardiac surgery is a dynamic, multifaceted process that extends beyond respiratory function alone. While most patients experience timely extubation, others face delayed or failed..

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Nursing management in extracorporeal membrane oxygenation (ECMO): A scoping review

Abstract Objectives To synthesise the existing literature on nursing management in the care of ECMO-supported patients, with a focus on: (1) the competencies required for ECMO nursing care, (2) the..

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Addressing metabolic demands during veno-venous extracorporeal life support: A narrative review

Abstract When critical illness is further complicated by severe respiratory failure, such as in cases of acute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO), patients may be..

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Prolonged Systemic Inflammatory Response Syndrome Predicts Atrial Fibrillation After Cardiac Surgery

Abstract Objectives Cardiac surgery and the use of cardiopulmonary bypass (CPB) lead to short-lasting postoperative inflammatory response and some patients fail to adapt to the stress leading to a prolonged..

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Standardization of in-vitro evaluation of extracorporeal life support (ECLS) devices for research and development

Abstract Extracorporeal life support (ECLS) technology has witnessed remarkable advancements during the last decades. However, further research and development of devices are required to increase, for example, performance-efficiency, hemocompatibility, and..

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Post-Decannulation Mortality in Patients on Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock

Abstract This retrospective single-center study evaluated adults with cardiogenic shock supported with veno-arterial extracorporeal membrane oxygenation (VA ECMO) from 2011 to 2023 to identify predictors of in-hospital mortality among those..

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The role of the perfusionist in the extracorporeal life support management: An international survey

Abstract Background Extracorporeal Life Support (ECLS) services are characterised by variability in resource availability, specific expertise, device management and team organisation, especially regarding the role of perfusionists. This international survey..

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Exploring the Role of Central Venous Pressure in Cardiac Surgery-Associated Acute Kidney Injury: A Comprehensive Scoping Review

Abstract Background: Acute kidney injury (AKI) is a critical complication, affecting up to 30% of coronary artery bypass grafting (CABG) patients, and contributing to significant morbidity and mortality. Recent studies indicate..

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Dose-response relationship between cell salvage volume, perioperative transfusion requirements, and postoperative clinical outcomes in cardiac surgery: A retrospective cohort study

Abstract Background Intraoperative cell salvage (CS) reduces allogeneic transfusion in cardiac surgery but depletes coagulation factors, potentially causing dose-dependent coagulopathy. Although mechanistic studies suggest hemostatic impairment at higher volumes, nearly..

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Novel insights into microcirculatory dysfunction in cardiogenic shock

Abstract While cardiogenic shock (CS) is classically defined by primary cardiac dysfunction leading to impaired macrocirculatory variables—such as hypotension, reduced cardiac output (CO), and diminished left ventricular ejection fraction—growing evidence..

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Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction

Abstract Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with..

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Extracorporeal membrane oxygenation without invasive mechanical ventilation for acute respiratory distress syndrome: an international cohort study Get access Arrow

Abstract Rationale In acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) without invasive mechanical ventilation (IMV) is particularly challenging. Objectives To study ARDS patients treated with ECMO to avoid..

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Compassionate Extracorporeal Membrane Oxygenation Discontinuation: A Narrative Review and Practical Process Model for Reliable End-of-Life Care

Abstract Background and Objectives: Extracorporeal membrane oxygenation (ECMO) provides temporary respiratory or circulatory support when conventional therapies fail. Some patients do not recover and are not candidates for transplant or..

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Technical feasibility of hyperbaric oxygen therapy for gas embolism with ECMO support: a brief report

Abstract Background Gas embolism (GE) occurs when gas enters into the circulation. Whilst small quantities of gas may be harmless, massive, or systemic GE may be life-threatening, when associated with..

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Postcardiotomy veno-arterial membrane oxygenation as a bridge to heart replacement therapies

Abstract Background Data on the outcome of veno-arterial extracorporeal membrane oxygenation (V-A-ECMO) support as a bridge to replacement therapies are scarce. Objectives We investigated the outcome of V-A-ECMO support after..

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Rhabdomyolysis-Associated Acute Kidney Injury: From Pathogenic Mechanisms to the Therapeutic Use of Sorbents

Abstract Background: Rhabdomyolysis is a pathological process that results from the breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, creatine kinase, potassium, and phosphate..

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Impact of an eCPR Pilot Program on Outcomes After Out-of-Hospital Cardiac Arrest for Patients Who Do Not Receive eCPR in…

Abstract Objectives Los Angeles County initiated an extracorporeal cardiopulmonary resuscitation (eCPR) program to transport patients with refractory shockable out-of-hospital cardiac arrest (OHCA) to dedicated eCPR-capable centers (ECCs). The impact of..

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Four Reasons ECMO Programs Stall

Abstract For many tertiary care hospitals, not offering extracorporeal membrane oxygenation (ECMO) is increasingly difficult to justify. Choosing not to offer ECMO means patients who could survive are instead transferred,..

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PRECISION study: impact of personalised cardiac anaesthesia and cerebral autoregulation on neurological outcomes in patients undergoing cardiac surgery – protocol…

Abstract Introduction Adverse neurological complications, including postoperative delirium (POD) and stroke, remain one of the major risks after cardiac surgery. A lack of comprehensive knowledge about their causes and neuroprotective strategies..

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How I manage drainage insufficiency on extracorporeal membrane oxygenation

Abstract While extracorporeal membrane oxygenation (ECMO) case volume continues to increase [, ], management of patients receiving ECMO remains technically challenging [, ]. Iatrogenic injury is a potential contributor to complications and..

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Evolving Concepts in Anticoagulation for VV-ECMO, VA-ECMO, and ECPR

  Evolving Concepts in Anticoagulation for VV-ECMO, VA-ECMO, and ECPR Moderator: Peter Schellongowski Speakers and Schedule: Anticoagulation and antiplatelets in VA ECMO Christophe Vandenbriele (London/United Kingdom) Anticoagulation and antiplatelets in..

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Organ donation after ECPR: ethical challenges and clinical implications

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) offers a life-saving option for select patients with refractory cardiac arrest, yet a substantial proportion suffer devastating neurological injury and die despite extracorporeal support. In..

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