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Purificación sanguínea inteligente para la estabilización hemodinámica en caso de choque vasopléjico

Con el uso de Cytosorb los datos clínicos actuales apuntan claramente a una estabilización rápida de la hemodinamia y las funciones orgánicas de los pacientes de cuidados intensivos con síndrome..

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Reduce peri-operative bleeding risk in patients on ticagrelor/rivaroxaban

The intraoperative use of the CytoSorb hemoadsorption in patients with ticagrelor or rivaroxaban treatment undergoing emergency open-heart operations is a safe and effective method to reduce bleeding complications and to..

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Reduce bleeding complications in patients on ticagrelor

Ticagrelor is a platelet aggregation inhibitor and is recommended in the current European Guidelines for the treatment of acute coronary syndrome and prevention of stent thrombosis.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Reduce-bleeding-complications-in-patients-on-ticagrelor_compressed.pdf" title="Reduce..

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Reducción de complicaciones hemorrágicas en pacientes sometidos a tratamiento con ticagrelor

El ticagrelor es un inhibidor de la agregación plaquetaria y se recomienda en las directrices europeas para el tratamiento del síndrome coronario agudo y para la profilaxis de la trombosis..

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Perioperative use of the extracorporeal cytokine adsorber CytoSorb in a patient with septic endocarditis

This case study reports on a 69-year-old female patient (pre-existing medical conditions: chronic heart failure NYHA III, Type 2 diabetes mellitus, multiple myeloma, chronic kidney disease stage 3), who was..

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Intraoperative extracorporeal cytokine adsorption in a case of cardiac transplant with congestive hepatitis post viral dilated cardiomyopathy

The following case study reports on a 13-year-old pediatric patient (body weight 45 kg) who was admitted to our hospital due to a deterioration in his clinical condition, after he..

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Intra- and postoperative use of CytoSorb in a patient with infective endocarditis, septic shock and myocardial infarction

This case reports on a 49-year-old previously healthy female patient, who presented to the Accident and Emergency Department of a peripheral hospital with complaints of breathlessness and fever for one..

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CytoSorb Therapy Intelligent Blood Purification for hemodynamic stabilization in vasoplegic shock

In these patients there is a high chance of success (shock reversal) possibly translating to survival benefits when the adsorber treatment is started in good time.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy_compressed.pdf" title="CytoSorb..

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CytoSorb Therapy Manage cytokine storm in patients with COVID-19

Limited treatment options are currently available for critically-ill COVID-19 ICU patients who may experience mortality rates up to 50%.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy-Manage-cytokine-storm-in-patients-with-COVID-19_compressed.pdf" title="CytoSorb Therapy Manage cytokine storm in patients with..

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CytoSorb Therapy enhanced ECMO

CytoSorb Therapy was prospectively applied and retrospectively analyzed to the control group, in patients with pneumogenic sepsis and ARDS until shock reversal was achieved   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-Therapy-enhanced-ECMO_compressed.pdf" title="CytoSorb Therapy enhanced..

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CytoSorb in the management of severe septic shock after coronary artery bypass graft surgery

This case reports on a 58-year-old male was hospitalized with a 2-day history of chest pain and dyspnea on exertion (New York Heart Association Class III).   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/CytoSorb-in-the-management-of-severe-septic-shock-after-coronary-artery-bypass-graft-surgery_compressed.pdf" title="CytoSorb..

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Cytosorb for Management of Acute Kidney Injury due to Rhabdomyolysis in a Child

This case reports on a 6-year-old, previously healthy girl who presented to the hospital with a febrile illness and profound pain in her lower extremities.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/Cytosorb-for-Management-of-Acute-Kidney-Injury-due-to-Rhabdomyolysis-in-a-Child_compressed.pdf" title="Cytosorb for..

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Terapia CytoSorb: Manejo de la tormenta de citokinas en pacientes con COVID-19

Actualmente se dispone de opciones de tratamiento limitadas para pacientes graves de COVID-19 en UCI, pudiendo alcanzar tasas de mortalidad de hasta el 50 %.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/cytosorb-covid19_compressed.pdf" title="cytosorb covid19_compressed"]  

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CytoSorb complementa la terapia ECMO

El tratamiento con CytoSorb se aplicó de forma prospectiva y se analizó de forma retrospectiva en el grupo de control, en los pacientes con sepsis de orígen pulmonar y SDRA..

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Neonatal and Pediatric General and Cardiac Anaesthesia and ICU: what’s new in 2017/2018 ? -Bari Pediatric Hospital Experience-Italy

Abstract This review wants to give an overview to most of the controversial fields in the clinical therapeutic assistance in neonatal and pediatric general and cardiothoracic surgery in anaesthesia and..

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In vitro assays and clinical trials in red blood cell aging: Lost in translation

Abstract The age of  (EC) in  and the  when transfusing long-term-stored EC are highly controversial issues. Whereas the definition of a short-term-stored EC or a long-term-stored EC is unclear in clinical trials, data..

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Identification of Plasma Metabolites Prognostic of Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass

Abstract Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass, but early detection of postoperative AKI remains challenging. Protein biomarkers predict AKI excellently in homogeneous cohorts but are..

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Assessment of Cerebral Autoregulation Patterns with Near-infrared Spectroscopy during Pharmacological-induced Pressure Changes

Abstract Background: Previous work has demonstrated paradoxical increases in cerebral oxygen saturation (ScO2) as blood pressure decreases and paradoxical decreases in ScO2 as blood pressure increases. It has been suggested that..

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Feasibility of smaller arterial cannulas in venoarterial extracorporeal membrane oxygenation

Abstract To facilitate venoarterial extracorporeal membrane oxygenation (ECMO) insertion for cardiogenic shock, we recently adopted a strategy of using a 15F arterial cannula in all patients, rather than 1 designed..

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Extracorporeal Life Support

Abstract This is a review of the University of Michigan experience with extracorporeal life support (ECLS) also known as extracorporeal membrane oxygenation (ECMO). Two thousand patients were managed with ECMO..

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Visceral organ protection in aortic arch surgery: safety of moderate hypothermia

Abstract OBJECTIVES Although antegrade selective cerebral perfusion (ASCP) provides good brain protection during aortic arch surgery, the issue of distal organ protection during circulatory arrest remains to be clarified. The..

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Platelet factor 4/heparin-particle gel immunoassay (PaGIA) is a weak method for heparin-induced thrombocytopenia (HIT) evaluation of post cardio-pulmonary bypass surgery…

Abstract Diagnosis of heparin induced thrombocytopenia (HIT) is not always easy, especially when a confirmatory functional test is not available. In most cases the diagnosis relies on the combination of..

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The Efficacy, Safety and Cost-Effectiveness of Intra-Operative Cell Salvage in High-Bleeding-Risk Cardiac Surgery with Cardiopulmonary Bypass: A Prospective Randomized and…

Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited...

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Post-Operative Bleeding Risk Stratification in Cardiac Pulmonary Bypass Patients Using Artificial Neural Network

Abstract The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data..

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Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial

Abstract Background The Organ Care System is the only clinical platform for ex-vivo perfusion of human donor hearts. The system preserves the donor heart in a warm beating state during..

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Ventricular assist devices: The future is now

Abstract Heart failure has become a global epidemic. For advanced heart failure, a broad assortment of device options have been introduced for both acute and prolonged intervals of  assistance. Durable implantable  (VADs)..

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Severe antiphospholipid syndrome and cardiac surgery: Perioperative management

Abstract Antiphospholipid syndrome is an antiphospholipid antibody-mediated prothrombotic state leading to arterial and venous thrombosis. This condition alters routine in-vitro coagulation tests, making results unreliable. Antiphospholipid syndrome patients requiring cardiac..

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Intra‐aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Abstract Background Intra‐aortic balloon pump counterpulsation (IABP) is currently the most commonly used mechanical assist device for patients with cardiogenic shock due to acute myocardial infarction. Although there has been..

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Timing and Strategy for Weaning From Venoarterial ECMO are Complex Issues

Abstract Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or..

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Tissue near infra red spectroscopy change is not correlated with patients' outcome in elective cardiac surgery

Abstract Background Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) are thought to be at the origin of organ dysfunction, although few studies have correlated microvascular alterations with outcome...

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