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Prevalence and Overtesting of True Heparin-Induced Thrombocytopenia in a 591-Bed Tertiary Care, Teaching Hospital

Abstract Heparin-induced thrombocytopenia type II (HIT) is a rare but potentially fatal antibody-mediated reaction to all forms of heparin (unfractionated heparin, low-molecular weight heparin, heparin flushes, and heparin-coated catheters), which..

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Normothermic Cardiopulmonary Bypass in Patient With Waldenström’s Macroglobulinemia and Cryoglobulinemia: A Case Report

Abstract Waldenström’s macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We..

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Brain-Dead Donors on Extracorporeal Membrane Oxygenation

Abstract Objectives:  To describe donors after brain death with ongoing extracorporeal membrane oxygenation and to analyze the outcome of organs transplanted from these donors. Design:  Retrospective analysis of the national..

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Pediatric Extracorporeal Membrane Oxygenation

Extracorporeal life support (ECLS), commonly referred to as extracorporeal membrane oxygenation (ECMO), is a modified form of cardiopulmonary bypass. Venous blood is drained from the patient and advanced to a..

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Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations

Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..

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Practice meta-environment of the cardiovascular perfusionist

Abstract Though historically the development of cardiovascular perfusion grew out of the need for cardiopulmonary bypass, the application of technologies of extracorporeal support has more recently expanded beyond the traditional..

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Differentiating between cold agglutinins and rouleaux: a case series of seven patients

Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..

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Operative strategies to reduce cerebral embolic events during on- and off-pump coronary artery bypass surgery: A stratified, prospective randomized trial

Abstract Objective To determine the impact of different  strategies on the incidence of cerebral embolic events during  (CABG). Methods Between 2012 and 2015, 142 patients with low-grade  (epiaortic ultrasound grade I/II) undergoing primary..

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The neurologic protection of unilateral versus bilateral antegrade cerebral perfusion in aortic arch surgery with deep hypothermic circulatory arrest: A…

Abstract Backgroud Unilateral and bilateral antegrade  (ACP) are recognized methods of cerebral protection in . However, the adequacy of cerebral protection in aortic arch surgery with  is controversial. In this study, we compared..

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Efficacy and safety of inhaled anaesthetic for postoperative sedation during mechanical ventilation in adult cardiac surgery patients: a systematic review…

Abstract The aim was to evaluate the efficacy and safety of volatile anaesthetic for postoperative sedation in adult cardiac surgery patients through a systematic review and meta-analysis. We retrieved randomized..

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Long-term survival and quality of life after extracorporeal life support: a 10-year report

Abstract OBJECTIVES:  Information is lacking about long-term survival and quality of life (QOL) after treating patients on extracorporeal life support. METHODS:  Outcome data were assessed by phone interviews, a QOL..

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Pneumonia after cardiac surgery: Experience of the National Institutes of Health/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network

Abstract Rationale Pneumonia remains the most common major infection after cardiac surgery despite numerous preventive measures. Objectives To prospectively examine the timing, pathogens, and risk factors, including modifiable management practices,..

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Antithrombin III is associated with acute liver failure in patients with end-stage heart failure undergoing mechanical circulatory support

Abstract Objective There are few data on the role of  in patients with end-stage heart failure supported by mechanical . The aim of our study was to investigate predictors for  in patients with..

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Thirty-Year Mortality After Coronary Artery Bypass Graft Surgery

Abstract Background Data are sparse on long-term mortality after coronary artery bypass graft (CABG) surgery. We examined short-term and long-term mortality of patients undergoing CABG surgery and a general population..

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Monitoring the quality of cardiac surgery based on three or more surgical outcomes using a new variable life-adjusted display

Abstract Quality problem or issue The traditional variable life-adjusted display (VLAD) is a graphical display of the difference between expected and actual cumulative deaths. The VLAD assumes binary outcomes: death..

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Air in intravenous lines: a need to review old opinions

Abstract At the time of writing this editorial, I have been in health care for exactly 45 years. These years have taken me through many challenging settings, including intensive cares,..

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Development and Evaluation of Heartbeat: A Machine Perfusion Heart Preservation System

Abstract Static cold storage is accompanied with a partial safe ischemic interval for donor hearts. In this current study, a machine perfusion system was built to provide a better preservation..

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Use of CytoSorb in a patient with septic shock in the context of mastitis and gangrenous cholecystitis

This report describes the case of a 63-year-old female patient, who was admitted to the Intensive Care Unit with the diagnosis of septic shock. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/03/caso-semana-cyto_compressed.pdf" title="caso semana cyto_compressed"]

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Neuroprotective effect of pressure-oriented flow regulation and pH-stat management in selective antegrade brain perfusion during total aortic arch repair

Abstract OBJECTIVES The aim of this study was to assess the safety and effectiveness of our selective antegrade brain perfusion (SABP) strategy, which is characterized by moderate hypothermic and low-pressure..

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Shortening cardioplegic arrest time in patients undergoing combined coronary and valve surgery: results from a multicentre randomized controlled trial: the…

Abstract OBJECTIVES:  Combined coronary artery bypass grafting and valve surgery requires a prolonged period of cardioplegic arrest (CA) predisposing to myocardial injury and postoperative cardiac-specific complications. The aim of this..

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Clear fluids fasting for elective paediatric anaesthesia

Guidelines for the management of pre-operative paediatric clear fluid fasting historically recommend a minimum of 2 h. In particular, the published guideline from European Society of Anaesthesiology (ESA) in 2011,..

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European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

The purpose of this guideline is to present evidence-based and consensus-based recommendations for the prevention and treatment of postoperative delirium. The cornerstones of the guideline are the preoperative identification and..

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International survey on the perioperative management of pulmonary endarterectomy: the perfusion perspective

Abstract Introduction: Pulmonary endarterectomy (PEA) is the most effective treatment available for chronic thromboembolic pulmonary hypertension (CTEPH). Patient selection, surgical technique and perioperative management have improved patient outcomes, which are..

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Measurement of gaseous microemboli in the prime before the initiation of cardiopulmonary bypass

Abstract Introduction: The use of cardiopulmonary bypass is associated with a risk of neurocognitive deficit caused by gaseous microemboli. Flushing the empty bypass circuit with carbon dioxide, which is more..

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Silicon Micropore‐Based Parallel Plate Membrane Oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) is a life support system that circulates the blood through an oxygenating system to temporarily (days to months) support heart or lung function during cardiopulmonary..

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Fluid Management in Cardiac Surgery: Results of a Survey in European Cardiac Anesthesia Departments

Abstract Objective To evaluate the current practice of perioperative fluid management in cardiac surgery patients. Design Multiple choice survey with 26 questions about existing practice of perioperative fluid management in..

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Hemodilution on Cardiopulmonary Bypass: Thromboelastography Patterns and Coagulation-Related Outcomes

Abstract Objective  has been associated with both  and  in studies based on  (TEG). Severe hemodilution during  (CPB) is a risk factor for morbidity in cardiac surgery. This study investigated the effects of different degrees..

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Safety of nitric oxide added to the ECMO circuit: a pilot study in children

Abstract We describe our experience of 30 consecutive children supported with ECMO and receiving 20 ppm of nitric oxide in the oxygenator of the ECMO circuit. Administration of nitric oxide..

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Independent Predictors of the Duration and Overall Burden of Postoperative Delirium After Cardiac Surgery in Adults: An Observational Cohort Study

Abstract Objective  (POD) is a common complication after cardiac surgery and is associated with increased patient morbidity and mortality. The objective of this study was to identify risk factors for..

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