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Platelet factor 4/heparin-particle gel immunoassay (PaGIA) is a weak method for heparin-induced thrombocytopenia (HIT) evaluation of post cardio-pulmonary bypass surgery…

Abstract Diagnosis of heparin induced thrombocytopenia (HIT) is not always easy, especially when a confirmatory functional test is not available. In most cases the diagnosis relies on the combination of..

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The Efficacy, Safety and Cost-Effectiveness of Intra-Operative Cell Salvage in High-Bleeding-Risk Cardiac Surgery with Cardiopulmonary Bypass: A Prospective Randomized and…

Abstract Objective: Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited...

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Post-Operative Bleeding Risk Stratification in Cardiac Pulmonary Bypass Patients Using Artificial Neural Network

Abstract The prediction of bleeding risk in cardiopulmonary bypass (CPB) patients plays a vital role in their postoperative management. Therefore, an artificial neural network (ANN) to analyze intra-operative laboratory data..

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Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial

Abstract Background The Organ Care System is the only clinical platform for ex-vivo perfusion of human donor hearts. The system preserves the donor heart in a warm beating state during..

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Ventricular assist devices: The future is now

Abstract Heart failure has become a global epidemic. For advanced heart failure, a broad assortment of device options have been introduced for both acute and prolonged intervals of  assistance. Durable implantable  (VADs)..

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Severe antiphospholipid syndrome and cardiac surgery: Perioperative management

Abstract Antiphospholipid syndrome is an antiphospholipid antibody-mediated prothrombotic state leading to arterial and venous thrombosis. This condition alters routine in-vitro coagulation tests, making results unreliable. Antiphospholipid syndrome patients requiring cardiac..

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Intra‐aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock

Abstract Background Intra‐aortic balloon pump counterpulsation (IABP) is currently the most commonly used mechanical assist device for patients with cardiogenic shock due to acute myocardial infarction. Although there has been..

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Timing and Strategy for Weaning From Venoarterial ECMO are Complex Issues

Abstract Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or..

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Tissue near infra red spectroscopy change is not correlated with patients' outcome in elective cardiac surgery

Abstract Background Microcirculatory disturbances following cardiac surgery with cardiopulmonary bypass (CPB) are thought to be at the origin of organ dysfunction, although few studies have correlated microvascular alterations with outcome...

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The prothrombotic paradox of severe obesity after cardiac surgery under cardiopulmonary bypass

Abstract Background Obesity is suggested to reduce postoperative bleeding in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) but perioperative hemostasis variations have not been studied. Therefore, we investigated the..

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Multidisciplinary Approach to Transvenous Lead Extraction: A Single Center’s Experience

Abstract Objective To evaluate the success and complication rates of a single center’s multidisciplinary approach to transvenous lead extraction. Setting One university hospital. Participants One hundred ninety-five patients scheduled for..

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Red Blood Cells and Mortality After Coronary Artery Bypass Graft Surgery: An Analysis of 672 Operative Deaths

Abstract Background Prior studies have implicated transfusion as a risk factor for mortality in coronary artery bypass graft surgery (CABG). To further our understanding of the true association between transfusion..

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Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery

Abstract Background. Invasive Mycobacterium chimaera infections were diagnosed in 2012 in 2 heart surgery patients on extracorporeal circulation. We launched an outbreak investigation to identify the source and extent of the potential outbreak..

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Genetic variation influences the risk of bleeding after cardiac surgery: novel associations and validation of previous findings

Abstract Background Severe post‐operative bleeding in cardiac surgery is associated with increased morbidity and mortality. We hypothesized that variation in genetic susceptibility contributes to post‐operative bleeding in addition to clinical..

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Combined Cerebral and Renal Near-Infrared Spectroscopy After Congenital Heart Surgery

Abstract The maintenance of an adequate oxygen supply to tissues after congenital heart surgery is essential for good outcomes. The objective of this study was to assess the usefulness of..

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Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass

Abstract Background: We designed a non-invasive, observational, real-time study, using near-infrared spectroscopy (NIRS) to assess the in vivo effects of cardiopulmonary bypass (CPB) on patients’ skeletal muscle as well as..

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Protection strategies during cardiopulmonary bypass

Abstract Purpose of review  To provide an update of research findings regarding the protection strategies utilized for patients undergoing cardiopulmonary bypass (CPB), including perioperative ventilatory strategies, different anesthetic regimens, and..

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Cardiogenic Shock

Cardiogenic Shock The unresolved clinical challenge. Cardiogenic shock (CS) can present in many different stages. It ranges from those at high risk of developing shock to those critically ill with..

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Sensation Fiber-optic IAB Catheter

Smaller catheters are better for the patient, potentially reducing vascular complications. Sensation 7 Fr. is the smallest IAB catheter available today.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/ca_sensation_brochure_9878_rev_a_eng-en-global_compressed.pdf"]  

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Cardiosave Intra-aortic Balloon Pump

[pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/cardiosave_brochure-en-non_us_canada_compressed.pdf"]  

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IAB Insertion / Cardiosave IABP Operation Quick Reference Guide

System performs Flat Arterial Pressure (A.P.) Surveillance checks and monitors for sustained loss of pulsatility on A.P. trace when pulsatility is expected   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/cardiosave_operation_guide-en-non_us_compressed.pdf"]  

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Optimizing IAB Therapy with Fiber-optics and High Efficacy Balloons

IAB therapy using a larger volume Sensation Plus® or Mega® balloon appears effective as a first line percutaneous mechanical circulatory support (MCS) strategy in a large fraction of critically ill..

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MetaVision Perfusion, Advanced patient data management system

Complete, accurate and consistent digital data management reduces the burden of peri and post-procedural case documentation.   [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/metavision_perfusion_brochure-en-global_compressed.pdf"]

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HL 40 Heart-Lung Machine (video)

The advanced perfusion features of the HL 40 support appropriate treatment. A familiar, perfusionist-developed interface minimizes the learning curve to reduce use errors. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/02/hl_40_brochure_mcp_br_10113_en-en-non_us_japan_compressed.pdf"]  

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HCU 40 Highest performance

Maquet’s heater-cooler unit HCU 40 is another current example of this innovation. Combining proven temperaturecontrol technology with outstanding performance and unique usability, the HCU 40 provides benefits for both the..

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Heater-Cooler Unit HCU 40 Proven Hygienic Safety

Heater-cooler devices control the patient’s blood temperature during extracorporeal perfusion. They are non-sterile devices used in the operating room outside the sterile fi eld. They have never been considered sterile..

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The role of fibrinogen and fibrinogen concentrate in cardiac surgery: an international consensus statement from the Haemostasis and Transfusion Scientific…

Abstract Summary To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity..

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High Hemoglobin Level As a Limiting Factor for Extracorporeal Membrane Oxygenation

Abstract We report the case of a 47 year old male who developed acute respiratory distress syndrome after bariatric surgery, requiring a venovenous extracorporeal membrane oxygenation. An inadequate extracorporeal membrane..

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Effect of nitric oxide on postoperative acute kidney injury in patients who underwent cardiopulmonary bypass: a systematic review and meta-analysis…

Abstract Background The effect of nitric oxide (NO) on renal function is controversial in critical illness. We performed a systematic meta-analysis and trial sequential analysis to determine the effect of..

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Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding

Abstract Thrombocytopenia and platelet dysfunction induced by extracorporeal blood circulation are thought to contribute to postsurgical bleeding complications in neonates undergoing cardiac surgery with cardiopulmonary bypass (CPB). In this study,..

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