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Evaluation of a New Sonoclot Device for Heparin Management in Cardiac Surgery

Abstract Background: Sonoclot is used to measure kaolin-based activated clotting time (kACT) for heparin management. Apart from measuring kACT, the device assesses the patient’s coagulation status by glass bead–activated tests..

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Numerical simulation of blood flow in femoral perfusion: comparison between side-armed femoral artery perfusion and direct femoral artery perfusion

Abstract Computational numerical analysis was performed to elucidate the flow dynamics of femoral artery perfusion. Numerical simulation of blood flow was performed from the right femoral artery in an aortic..

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Long‐Term Intra‐Aortic Balloon Pump Support as Bridge to Left Ventricular Assist Device Implantation

Abstract Background The intra‐aortic balloon pump (IABP) can be used to bridge critically ill end‐stage heart failure patients to left ventricular assist device (LVAD) implantation. However, the IABP's potential association..

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Brain in Congenital Heart Disease Across the Lifespan

Abstract The number of patients surviving with congenital heart disease (CHD) has soared over the last 3 decades. Adults constitute the fastest-growing segment of the CHD population, now outnumbering children...

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Evaluation of Capiox RX25 and Quadrox‐i Adult Hollow Fiber Membrane Oxygenators in a Simulated Cardiopulmonary Bypass Circuit

Abstract The Capiox RX25 and Quadrox‐i Adult oxygenators are commonly used in clinical adult cardiopulmonary bypass circuits. This study was designed to test the effectiveness of two adult oxygenators in..

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Does sinus rhythm conversion after cardiac surgery affect postoperative health- related quality of life?

Abstract Background We investigated the impact and the predictive value of sinus rhythm at 12 months (SR12) on subscales of three different HrQoL questionnaires: SF-36., EuroQoL and MFI 20. Methods..

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Carotid Artery Dissection Following Neck Cannulation for Extracorporeal Life Support

Abstract A term neonate was cannulated for venoarterial extracorporeal life support (ECLS) via the right neck for non-postoperative junctional ectopic tachycardia. Initial echocardiogram demonstrated an echogenic strand in the transverse..

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Neurodevelopmental outcome in hypoplastic left heart syndrome: Impact of perioperative cerebral tissue oxygenation of the Norwood procedure

Abstract Objectives Patients with  are at risk for neurodevelopmental impairment.  during neonatal treatment might be a relevant cause. We evaluated the association between cerebral oxygenation in the perioperative course of the  and neurodevelopmental..

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Improved hemocompatibility of silicone rubber extracorporeal tubing via solvent swelling-impregnation of S-nitroso-N-acetylpenicillamine (SNAP) and evaluation in rabbit thrombogenicity model

Abstract Blood-contacting devices, including extracorporeal circulation (ECC) circuits, can suffer from complications due to platelet activation and thrombus formation. Development of nitric oxide (NO) releasing polymers is one method to..

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Effect of Exogenous Albumin on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Off-pump Coronary Artery Bypass Surgery…

Abstract Background Hypoalbuminemia may increase the risk of acute kidney injury (AKI). The authors investigated whether the immediate preoperative administration of 20% albumin solution affects the incidence of AKI after..

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Intraoperative Red Blood Cell Transfusion in Infant Heart Transplant Patients Is Not Associated with Worsened Outcomes

Abstract BACKGROUND:  Red blood cell (RBC) transfusion is common during infant cardiac surgery. A previous report of pediatric heart transplant recipients showed that increased RBC transfusion volume was independently associated..

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Thromboelastography—does it impact blood component transfusion in pediatric heart surgery?

Abstract Background The administration of blood products during pediatric cardiac surgery is common. We sought to determine if thromboelastography (TEG) is a cost-effective tool to reduce blood product transfusion in..

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A Multicenter, Open-Label, Randomized Controlled Trial of a Conservative Fluid Management Strategy Compared With Usual Care in Participants After Cardiac…

Abstract OBJECTIVES:  There is little evidence to guide fluid administration to patients admitted to the ICU following cardiac surgery. This study aimed to determine if a protocolized strategy known to..

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Device-Induced Hemostatic Disorders in Mechanically Assisted Circulation

Abstract Mechanically assisted circulation (MAC) sustains the blood circulation in the body of a patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) or on ventricular assistance with a ventricular assist..

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Hemoadsorption during Cardiopulmonary Bypass in Patients with Endocarditis Undergoing Valve Surgery: A Retrospective Single-Center Study

Abstract Background: Aim of this study was to evaluate the outcomes of endocarditis patients undergoing valve surgery with the Cytosorb® hemoadsorption (HA) device during cardiopulmonary bypass. Methods: From 2009 until 2019,..

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Incidence and impact of silent brain lesions after coronary artery bypass grafting

Abstract Objective Silent brain lesions are known to occur after coronary artery bypass grafting (CABG). The aim of this study was to seek the incidence rate, the influence of procedures,..

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Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support

Abstract Thrombocytopenia and impaired platelet function are known as intrinsic drawbacks of cardiac surgery and extracorporeal life supports (ECLS). A number of different factors influence platelet count and function including..

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Contrast media exposure in the perioperative period confers no additional risk of acute kidney injury in infants and young children…

Abstract Background Recently, there has been an interest in the temporal relationship between contrast exposure (CM) and cardiac surgery suggesting that a “double hit” on the kidney function in close..

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Bilirubine and lactate: easy to determine and valuable to predict outcome in cardiac surgery

Abstract BACKGROUND: Cardiopulmonary bypass during cardiac surgery is associated with metabolic changes after operation and results inter alia in increased levels of lactate and bilirubin. Since prediction of the course..

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Disseminated Intravascular Coagulation: A Practical Approach

Abstract Anesthesiologists may encounter patients with disseminated intravascular coagulation, a potential complication of severe sepsis or major trauma. This practical guide discusses the clinical approach, laboratory diagnosis, and current management..

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Rewarming Temperature During Cardiopulmonary Bypass and Acute Kidney Injury: A Multicenter Analysis

Abstract Background  (AKI) after  (CPB) is associated with a requirement for dialysis, a longer stay in the intensive care unit, a longer hospital length of stay, and mortality. An  arterial outlet temperature..

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Levosimendan Prevents Pressure-Overload-induced Right Ventricular Failure

Abstract Background:  We investigated if chronic levosimendan treatment can prevent and revert pressure-overload–induced right ventricular hypertrophy and failure in rats. Methods:  Right ventricular hypertrophy and failure was induced in Wistar..

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Peripartum Cardiomyopathy

Abstract Peripartum cardiomyopathy is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period and is marked by left ventricular dysfunction and heart failure. The disease is relatively..

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Report of the National Heart, Lung, and Blood Institute Working Group

Abstract The National Heart, Lung, and Blood Institute convened a working group in January 2015 to explore issues related to an integrated data network for congenital heart disease research. The..

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Antegrade and Retrograde Cerebral Perfusion During Acute Type A Aortic Dissection Repair in 290 Patients

Abstract Aim Hypothermia and selective brain perfusion is used for brain protection during an acute type A aortic dissection (ATAAD) correction. We compared the outcomes between antegrade and retrograde cerebral..

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Integral Use of Thromboelastography With Platelet Mapping to Guide Appropriate Treatment, Avoid Complications, and Improve Survival of Patients With Coronavirus…

Abstract Objectives:  Coagulopathy of coronavirus disease 2019 is largely described as hypercoagulability, yet both thrombotic and hemorrhagic complications occur. Although therapeutic and prophylactic anticoagulant interventions have been recommended, empiric use..

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ECPella: Concept, Physiology and Clinical Applications

Abstract Addition of Impella on top of venoarterial extracorporeal membrane oxygenation (VA-ECMO) has gained wide interest as it might portend improved outcomes in patients with cardiogenic shock. This has been..

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Use of CytoSorb in a patient requiring resuscitation due to drug intoxication with consecutive multiple organ failure

This case reports on a 52-year-old female patient who was hospitalized via the ambulance service post resuscitation in the context of drug intoxication with metoprolol, benzodiazepine and hydromorphine, as it..

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The incidence and importance of anaemia in patients undergoing cardiac surgery in the UK – the first Association of Cardiothoracic…

Abstract The importance and variability of pre‐operative anaemia in cardiac surgical patients across the UK is not known, and there is debate about its association with patient outcomes. The Association..

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Optimizing Thrombin Generation with 4-Factor Prothrombin Complex Concentrates in Neonatal Plasma After Cardiopulmonary Bypass

Abstract BACKGROUND:  Bleeding is a serious complication after pediatric cardiopulmonary bypass (CPB) that is associated with an increase in perioperative morbidity and mortality. Four-factor prothrombin complex concentrates (4F-PCCs) have been..

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