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Stopping versus continuing acetylsalicylic acid before coronary artery bypass surgery: A systematic review and meta-analysis of 14 randomized controlled trials…

Abstract This study aimed to evaluate the efficacy and safety of continuing versus stopping aspirin [acetylsalicylic acid (ASA)] preoperatively in patients undergoing coronary artery bypass graft surgery. MEDLINE, EMBASE, CENTRAL/Cochrane..

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Postoperative bleeding in coronary artery bypass patients on double antiplatelet therapy: predictive value of preoperative aggregometry†

Abstract OBJECTIVES We tested the possible value of routine aggregometry testing for bleeding prediction following coronary artery bypass grafting in patients who received preoperative double antiplatelet therapy. METHODS In 226..

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Medium-term survival after surgery for acute Type A aortic dissection is improving

Abstract OBJECTIVES To report long-term survival and predictors of mortality in patients included in a large, contemporary, multicentre, multinational database: Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD), which..

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An innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit

Abstract Context:  Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of..

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Optimal blood pressure during cardiopulmonary bypass defined by cerebral autoregulation monitoring

Abstract Objectives We sought to define the lower and upper limits of cerebral blood flow autoregulation and the optimal blood pressure during cardiopulmonary bypass. We further sought to identify variables..

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Long-term outcomes following minimal invasive versus conventional aortic valve replacement: a propensity match analysis

Abstract INTRODUCTION: Minimal invasive aortic valve replacement has become a routine procedure. In this study, we compared the outcomes between conventional and minimal invasive aortic valve replacement via the partial..

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Narrative feedback from OR personnel about the safety of their surgical practice before and after a surgical safety checklist intervention

Abstract Objective To examine narrative feedback to understand surgical team perceptions about surgical safety checklists (SSCs) and their impact on the safety of surgical practice. Design We reviewed free-text comments..

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Postoperative acute kidney injury following intraoperative blood product transfusions during cardiac surgery

Abstract Introduction: This study explored the nature of the association between intraoperative usage of red blood cell, fresh frozen plasma, cryoprecipitate or platelet transfusions and acute kidney injury. Methods: A..

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The role of extracorporeal membrane oxygenator therapy in the setting of Type A aortic dissection

Abstract Background and Aim Patients presenting with type A aortic dissection (TAAD) present with a wide clinical spectrum ranging from hemodynamic stability to multiorgan malperfusion with cardiovascular collapse. Extracorporeal membrane..

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Is the use of hydroxyethyl starch as priming solution during cardiac surgery advisable? A randomized, single-center trial

Abstract Introduction: The use of cardiopulmonary bypass (CPB) leads to increased fluid filtration and edema. The use of artificial colloids to counteract fluid extravasation during cardiac surgery is controversial. Beneficial..

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Extracorporeal Membrane Oxygenation

Abstract Over the years, there have been many innovations that have come and gone. It is not often that a single idea dramatically changes how critical care is delivered. Since..

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Bleeding during veno-venous ECMO cannot reliably be predicted by rotational thrombelastometry (ROTEM™)

Abstract Introduction: Veno-venous extracorporeal membrane oxygenation (vvECMO) used for respiratory support is associated with clinical bleeding in at least one third of patients. Mechanisms promoting bleeding, like acquired von Willebrand..

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Independent Predictors of the Duration and Overall Burden of Postoperative Delirium After Cardiac Surgery in Adults: An Observational Cohort Study

Abstract Objective  (POD) is a common complication after cardiac surgery and is associated with increased patient morbidity and mortality. The objective of this study was to identify risk factors for..

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Relationship Between Transfusion of Blood Products and the Incidence of Thrombotic Complications in Neonates and Infants Undergoing Cardiac Surgery

Abstract Objectives The authors hypothesized that transfusion of blood products in neonates and infants undergoing high-risk cardiac surgery in the absence of intraoperative coagulation monitoring increases the risk of thrombotic..

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The use of preoperative aspirin in cardiac surgery: A systematic review and meta‐analysis

Abstract Background Despite the fact that aspirin is of benefit to patients following coronary artery bypass grafting (CABG), continuation or administration of preoperative aspirin before CABG or any cardiac surgical..

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Lactate and Echocardiography Before Veno-Venous Extracorporeal Membrane Oxygenation Support

Abstract Background Lactate has been recognised as a  in several critical conditions. Veno-Venous  (VV-ECMO) is a well-established therapy in patients with  Syndrome (ARDS) unresponsive to conventional therapy and  pre ECMO initiation has been recently..

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Decreases in Mixed Venous Blood O2 Saturation in Cardiac Surgery Patients Following Extubation

Abstract Background: Decreases in mixed venous O2 saturation (SvO2) have been reported to occur in postcardiac surgery patients during weaning from mechanical ventilation. Our aim was to establish whether the physiological..

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Effect of Cerebral Embolic Protection Devices on CNS Infarction in Surgical Aortic Valve Replacement

Abstract Importance   Stroke is a major complication of surgical aortic valve replacement (SAVR). Objective   To determine the efficacy and adverse effects of cerebral embolic protection devices in reducing ischemic central..

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A Risky Proposition: Blood Transfusion and the Risk of Surgical Site Infections

Abstract In our perpetually evolving pursuit to optimize the risk-benefit profile of perioperative interventions, the decision to administer allogeneic blood products is fraught with extraordinarily conflicting goals. This infographic summarizes..

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Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery

Abstract BACKGROUND:  Declining platelet counts may reveal platelet activation and aggregation in a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts after on-pump coronary artery bypass grafting (CABG)..

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Cardiopulmonary Resuscitation in Adults and Children With Mechanical Circulatory Support: A Scientific Statement From the American Heart Association

Abstract Cardiac arrest in patients on mechanical support is a new phenomenon brought about by the increased use of this therapy in patients with end-stage heart failure. This American Heart..

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Effect of Levosimendan on Low Cardiac Output Syndrome in Patients With Low Ejection Fraction Undergoing Coronary Artery Bypass Grafting With…

Abstract Importance   Low cardiac output syndrome after cardiac surgery is associated with high morbidity and mortality in patients with impaired left ventricular function. Objective   To assess the ability of preoperative..

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Right atrial pressure and venous return during cardiopulmonary bypass

Abstract The relevance of right atrial pressure (RAP) as the backpressure for venous return (QVR) and mean systemic filling pressure as upstream pressure is controversial during dynamic changes of circulation...

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Insidious Risk of Severe Mycobacterium chimaera Infection in Cardiac Surgery Patients

Abstract Background. An urgent UK investigation was launched to assess risk of invasive Mycobacterium chimaera infection in cardiothoracic surgery and a possible association with cardiopulmonary bypass heater-cooler units following alerts in Switzerland..

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Renal haemodynamics and oxygenation during and after cardiac surgery and cardiopulmonary bypass

Abstract Acute kidney injury (AKI) is a common complication following cardiac surgery performed on cardiopulmonary bypass (CPB) and has important implications for prognosis. The aetiology of cardiac surgery‐associated AKI is..

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Novel Rotational Speed Modulation System Used With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Femoral venoarterial  (VA-ECMO) is widely used to maintain blood flow in patients with . However, retrograde blood flow increases left ventricular (LV) afterload during femoral VA-ECMO. Additional support by means..

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Predictable capability control scheme for oxygen-exchange blood flow regulation in an extracorporeal membrane oxygenation system

Abstract Extracorporeal membrane oxygenation system is used for rescue treatment strategies for temporary cardiopulmonary function support to facilitate adequately oxygenated blood to return into the systemic and pulmonary circulation systems...

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Bleeding and thrombosis associated with ventricular assist device therapy

Abstract Over the past decade, continuous-flow rotary pumps have dramatically improved survival for patients with advanced . Bleeding and thrombosis, however, continue to be the Achilles heel of  (LVAD) therapy. There is..

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2016 survey about temperature management during extracorporeal circulation in China

Abstract Objective: In order to assess the current status of temperature management during cardiopulmonary bypass (CPB) in China and, thereby, implement standardized management protocols, the authors carried out a national..

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