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European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium

The purpose of this guideline is to present evidence-based and consensus-based recommendations for the prevention and treatment of postoperative delirium. The cornerstones of the guideline are the preoperative identification and..

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International survey on the perioperative management of pulmonary endarterectomy: the perfusion perspective

Abstract Introduction: Pulmonary endarterectomy (PEA) is the most effective treatment available for chronic thromboembolic pulmonary hypertension (CTEPH). Patient selection, surgical technique and perioperative management have improved patient outcomes, which are..

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Measurement of gaseous microemboli in the prime before the initiation of cardiopulmonary bypass

Abstract Introduction: The use of cardiopulmonary bypass is associated with a risk of neurocognitive deficit caused by gaseous microemboli. Flushing the empty bypass circuit with carbon dioxide, which is more..

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Silicon Micropore‐Based Parallel Plate Membrane Oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) is a life support system that circulates the blood through an oxygenating system to temporarily (days to months) support heart or lung function during cardiopulmonary..

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Fluid Management in Cardiac Surgery: Results of a Survey in European Cardiac Anesthesia Departments

Abstract Objective To evaluate the current practice of perioperative fluid management in cardiac surgery patients. Design Multiple choice survey with 26 questions about existing practice of perioperative fluid management in..

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Hemodilution on Cardiopulmonary Bypass: Thromboelastography Patterns and Coagulation-Related Outcomes

Abstract Objective  has been associated with both  and  in studies based on  (TEG). Severe hemodilution during  (CPB) is a risk factor for morbidity in cardiac surgery. This study investigated the effects of different degrees..

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Safety of nitric oxide added to the ECMO circuit: a pilot study in children

Abstract We describe our experience of 30 consecutive children supported with ECMO and receiving 20 ppm of nitric oxide in the oxygenator of the ECMO circuit. Administration of nitric oxide..

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Independent Predictors of the Duration and Overall Burden of Postoperative Delirium After Cardiac Surgery in Adults: An Observational Cohort Study

Abstract Objective  (POD) is a common complication after cardiac surgery and is associated with increased patient morbidity and mortality. The objective of this study was to identify risk factors for..

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Posttransfusion Increase of Hematocrit per se Does Not Improve Circulatory Oxygen Delivery due to Increased Blood Viscosity

Abstract BACKGROUND:  Blood transfusion is used to treat acute anemia with the goal of increasing blood oxygen-carrying capacity as determined by hematocrit (Hct) and oxygen delivery (DO2). However, increasing Hct..

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Remote ischaemic preconditioning reduces acute kidney injury in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a meta-analysis

Abstract This article represents the first attempt to perform a pooled analysis about remote ischaemic preconditioning (RIPC) in reduction of acute kidney injury (AKI) of adult patients undergoing cardiac surgery..

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Direct oral anticoagulants and heparins: laboratory values and pitfalls in ‘bridging therapy’

Abstract OBJECTIVES:  The three direct oral anticoagulants (DOACs) dabigatran, apixaban and rivaroxaban are now widely used in clinical practice. For patients requiring perioperative interruption of DOACs, heparin bridging is still..

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Aortic root surgery with circulatory arrest: Predictors of prolonged postoperative hospital stay

Abstract Objective Little is known about the outcomes of  operations that involve inducing hypothermic circulatory arrest for relatively extensive proximal . We attempted to identify predictors of postoperative hospital length of stay..

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NGAL expression during cardiopulmonary bypass does not predict severity of postoperative acute kidney injury

Abstract Background Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is..

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Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model.

Abstract OBJECTIVES:  This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy phosphates during cardiac arrest..

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External validation of predictive models for acute kidney injury following cardiac surgery

Abstract BACKGROUND  Four predictive models for acute kidney injury associated with cardiac surgery were developed by Demirjian in the United States in 2012. However, the usefulness of these models in..

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Recirculation in Extracorporeal Membrane Oxygenation: The Warning Comes From the Cannula

We are writing to point out a simple clinical sign in a pedagogic way, about recirculation in venovenous extracorporeal membrane oxygenation (ECMO). These last years, ECMO has emerged as a..

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Enhanced Hemocompatibility and In Vivo Analytical Accuracy of Intravascular Potentiometric Carbon Dioxide Sensors via Nitric Oxide Release

Abstract In this letter, the innate ability of nitric oxide (NO) to inhibit platelet activation/adhesion/thrombus formation is employed to improve the hemocompatibility and in vivo accuracy of an intravascular (IV) potentiometric PCO2 (partial pressure..

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Air embolism: diagnosis and management

Abstract Air embolism is an uncommon, but potentially life-threatening event for which prompt diagnosis and management can result in significantly improved patient outcomes. Most air emboli are iatrogenic. Arterial air..

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Do we have enough evidence for minimally-invasive cardiac surgery? A critical review of scientific and non-scientific information

Abstract Reducing surgical trauma by minimizing skin incisions has transformed abdominal surgery resulting in significant improvements in outcome. In cardiac surgery, such efforts have also been made, but similar benefits..

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In Vitro Evaluation of Pediatric Hollow‐Fiber Membrane Oxygenators on Hemodynamic Performance and Gaseous Microemboli Handling: An International Multicenter/Multidisciplinary Approach

Abstract The objective of this study was to compare the hemodynamic performances and gaseous microemboli (GME) handling ability of two pediatric oxygenators in a simulated pediatric cardiopulmonary bypass (CPB) model..

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Accuracy of predicted haemoglobin concentration on cardiopulmonary bypass in paediatric cardiac surgery: effect of different formulae for estimating patient blood…

Abstract Introduction: When applying a blood-conserving approach in paediatric cardiac surgery with the aim of reducing the transfusion of homologous blood products, the decision to use blood or blood-free priming..

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Postoperative Bleeding After Change in Heparin Supplier: A Cardiothoracic Center Experience

Abstract Objective Unfractionated heparin is a mixture of  with different pharmacologic and  properties. The literature suggests that blood loss after cardiac surgery is related to both elevated postoperative heparin concentrations and the..

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Development of a high fidelity pressurized porcine beating heart simulator for cardiac surgery training

Abstract Background: Development of a high-fidelity cardiac surgery simulator (CSS) requires integration of a heart model with a mock cardiopulmonary bypass (CPB) circuit that can provide feedback to mimic the..

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Mycobacterium chimaera left ventricular assist device infections

Abstract A global outbreak of invasive Mycobacterium chimaera infections after cardiac surgery has recently been linked to bioaerosols from contaminated heater‐cooler units. The majority of cases have occurred after valvular surgery or..

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Thromboelastography during coronary artery bypass grafting surgery of severe hemophilia A patient – the effect of heparin and protamine on…

Abstract Coronary artery bypass grafting surgery (CABG) in hemophilia patients is challenging. Thromboelastography (TEG) is useful to assess hemostasis perioperatively. A patient with severe hemophilia A underwent CABG with TEG studies...

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Anticoagulation and Transfusions Management in Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: Assessment of Factors Associated With Transfusion…

Abstract Purpose: We describe an approach for anticoagulation and transfusions in veno-venous–extracorporeal membrane oxygenation (VV-ECMO), evaluating factors associated with higher transfusion requirements, and their impact on mortality. Methods: Observational study..

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Utility of Sonoclot in Prediction of Postoperative Bleeding in Pediatric Patients Undergoing Cardiac Surgery for Congenital Cyanotic Heart Disease: A…

Abstract Objectives To assess the utility of Sonoclot in prediction of  in pediatric patients undergoing cardiac surgery with  for . Design Prospective, . Setting Single university hospital. Participants Eighty-seven pediatric patients undergoing cardiac surgery..

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Colloids in Cardiac Surgery—Friend or Foe?

Abstract Objective The right choice of fluid replacement still is a matter of debate. Recently, two large-scale studies on the use of  (HES) in the intensive care setting have been published,..

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Pushing the boundaries of ECLS: Outcomes in < 34 week EGA neonates

Abstract Purpose  (ECLS) is usually reserved for infants ≥ 34 weeks estimated  (EGA) owing to concerns about increased mortality and incidence of  (ICH). We sought to characterize survival, rates of ICH, and complications in..

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