Single coronary artery is a rare congenital anomaly with a quoted incidence of 0.024% to 0.06% (), and may be associated with sudden cardiac death after exercise and angina. We..
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Transposition is the condition in which the great arteries take origin from the ventricles in reverse position across (“trans”) the ventricular septum: the aorta from the right ventricle and the..
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A sinus of valsalva aneurysm (SOVA) is an abnormal dilatation of the aortic root located between the aortic valve annulus and the sinotubular junction. It occurs as a consequence of..
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Aneurysms of the sinus of Valsalva are extremely rare. Ruptured aneurysms of the sinus of Valsalva are frequently associated with other congenital defects, particularly with ventricular septal defect, aortic valve..
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Congenital heart diseases that cause obstruction of the right ventricular outflow tract are often difficult to diagnose. We report the case of a 49-year-old man who presented with long-standing shortness..
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Congenital heart diseases that cause obstruction of the right ventricular outflow tract are often difficult to diagnose. We report the case of a 49-year-old man who presented with long-standing shortness..
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Partial anomalous pulmonary venous connection (PAPVC) is a rare congenital cardiac defect. As the name suggests, in PAPVC, the blood flow from a few of the pulmonary veins return to..
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Background There is a high mortality in infants with right atrial isomerism (RAI). However, less is known about outcome in older children with RAI. This study sought to evaluate those..
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The term “atrioventricular septal defect” (AVSD) covers a spectrum of congenital heart malformations characterised by a common atrioventricular junction coexisting with deficient atrioventricular septation. In ostium primum atrial septal defect..
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Abstract Background and Objectives Heparin-induced thrombocytopenia (HIT) is an antibody-mediated condition that leads to thrombocytopenia and possible thrombosis. Patients with HIT who require cardiac surgery pose a challenge as high..
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Abstract Postoperative coagulopathic bleeding is common in cardiac surgery and is associated with increased morbidity and mortality. Ideally, real-time information on in-vivo coagulation should be available. However, up to now..
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Abstract Objectives: Evaluating whether there is a clinical benefit of using extracorporeal cytokine adsorption therapy in two indications. Design: Systematic review. Setting: Search on four databases, Medline, Embase, The Cochrane..
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Abstract Objective Dysregulation of local nitric oxide (NO) synthetases occurs during and reperfusion associated with , (DHCA), and reperfusion. Rapid fluctuations in local occurring in neonates and infants probably contribute to inflammation-induced microglial activation..
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This case reports on a 53-year-old female patient who was transferred from the isolation ward to the Medical Intensive Care Unit due to progressive respiratory deterioration in the context of..
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Abstract Cardioplegia is used to induce cardiac arrest in order to facilitate cardiac surgery in patients supported by cardiopulmonary bypass. It is administered directly into the coronary vessels after the..
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Abstract Background The effectiveness and safety of non-heparin anticoagulants for the treatment of heparin-induced thrombocytopenia (HIT) are not fully established, and the optimal treatment strategy is unknown. In a systematic..
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Abstract Purpose: Purpose: Condensation that clogs the hollow fibers of the oxygenation and accumulation of plasma leaks reduces oxygenated lung capacity. In this study, artificial We evaluated whether monitoring changes..
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Abstract Introduction: The contribution of fluid temperature to the effect of crystalloid fluid bolus therapy (FBT) in post-cardiac surgery patients is unknown. We evaluated the hemodynamic effects of FBT with..
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Abstract Background Several aquatic organisms such as loaches have evolved unique intestinal breathing mechanisms to survive under extensive hypoxia. To date, it is highly controversial whether such capability can be..
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Abstract Objective Timing and causes of hospital mortality in adult patients undergoing veno-arterial extracorporeal membrane oxygenation (V-A ECMO) have been poorly described. Aim of the current review was to investigate..
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Abstract Objectives: Cardiac surgery using cardiopulmonary bypass frequently provokes a systemic inflammatory response syndrome. This can lead to the development of low cardiac output syndrome (LCOS). Both of these can..
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Abstract Introduction Cardiopulmonary bypass (CPB) is a common procedure to maintain body perfusion during cardiac surgery. It is associated with a systemic inflammatory response, hemostasis and circulatory dysfunction that can..
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Abstract Background: Due to the substantial improvement in survival among pediatric patients undergoing congenital heart surgery, reducing early and long-term morbidity is becoming the major focus of care. Blood transfusion is..
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Abstract The outbreak of the novel coronavirus pandemic (COVID-19) has resulted in dramatic changes to the conduct of surgery both from a patient management perspective and in protecting healthcare providers...
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Abstract Background We sought to determine differences in the circulating metabolic profile of infants with or without acute kidney injury (AKI) following cardiothoracic surgery with cardiopulmonary bypass (CPB). Methods We..
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Abstract Background Cerebral autoregulation mechanisms help maintain adequate cerebral blood flow (CBF) despite changes in cerebral perfusion pressure. Impairment of cerebral autoregulation, during and after cardiopulmonary bypass (CPB), may increase..
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Abstract The importance of teamwork in health care delivery and patient safety is increasingly being recognized and has benefitted substantially by adopting a human factors' perspective and approach. The scientific..
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Abstract Objectives: Cardiopulmonary bypass surgery is complicated by metabolic acidosis, microvascular dysfunction, and capillary leak. The glycocalyx—a layer of proteins and sugars lining the vascular endothelium—is degraded during cardiopulmonary bypass...
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Abstract Background Recurrent observation of clot in the cardiopulmonary bypass circuit after the administration of a protamine test dose (PTD) prompted concern over the effects of PTDs on patient activated..
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