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Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine

Abstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...

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Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients

Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..

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Effect of Perioperative Lipid Status on Clinical Outcomes after Cardiac Surgery

Abstract Patients undergoing cardiac surgery are at increased cardiovascular risk, which includes altered lipid status. However, data on the effect of cardiac surgery and cardiopulmonary bypass (CPB) on plasma levels..

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Comparison of del Nido Cardioplegia vs blood cardioplegia in adult aortic surgery is the single-dose cardioplegia technique really advantageous?

Abstract Background Objective: The aim of the present study was to compare the operative and early postoperative results of the use of del Nido  solution (dNCS) with traditional blood cardioplegia..

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Management of vascular access for extracorporeal life support: A cohort study

Abstract Extracorporeal membrane oxygenation (ECMO) is required for patients with refractory cardiac or respiratory failure. Inadequate securement of ECMO cannulae may lead to adverse events, ranging from line kinking to..

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Invasive Left Atrial Pressure Monitoring and Survival on Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock

Abstract Introduction: Elevated left atrial pressures (LAP) are associated with worse outcomes among patients with cardiogenic shock (CS), yet there are limited data on the utility of continuous invasive monitoring of..

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Introducing E-SIM series

Introducing the most advanced ECLS simulators- "E-SIM Series" Featuring: 1. All types of ECLS cannulation capabilities. 2. Perfusion troubleshooting simulation scenarios controlled via a remote control 3. Ultrasound guided cannulation..

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Post MI VSR repair via LT and RT ventricular approach

Post MI VSR repair via LT and RT ventricular approach excluding technique and closure LV with teflon felt.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as..

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Inferior Vena Cava - Vena Cava inferior

In this video I will show you everything you need to know about the inferior vena cava (IVC).   En este video les dire todo acerca de la vena cava..

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Aortic Valve Replacement and transverse aortoplasty

A to Z steps of AVR and transverse aortoplasty in patient with severe AS and aortic dilatation as well as implanted On X new generation valve in aortic position. [gallery..

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Uncontrolled Donation after Cardiac Death

Uncontrolled Donation after Cardiac Death. [playlist ids="21095"]   Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head of IUMS transplant and cardiovascular surgery department...

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Aortic root abscess

An aortic root abscess is a serious complication of infective endocarditis and most commonly seen in patients who have had aortic root repair and/or aortic valve replacement. Aortic root abscess..

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Blood purification during valve surgery for infective endocarditis in an adolescent

This case reports on a 15-year old boy with history of bicuspid valve and mild aortic valve regurgitation, who had a recent history of abdominal pain, diarrhea, and vomiting. [pdf-embedder..

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Pilot Study of a Novel Gelatin-based Model for Venovenous Extracorporeal Membrane Oxygenation Cannula Insertion Simulation

Abstract Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is a form of mechanical support used in respiratory failure refractory to conventional medical management. Because VV ECMO cannulation is an uncommonly performed,..

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Advances in extracorporeal membrane oxygenator design for artificial placenta technology

Abstract Extreme prematurity, defined as a gestational age of fewer than 28 weeks, is a significant health problem worldwide. It carries a high burden of mortality and morbidity, in large..

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Performance of Lactate and CO2-Derived Parameters in Predicting Major Postoperative Complications After Cardiac Surgery With Cardiopulmonary Bypass: Protocol of a…

Abstract Background: CO2-derived parameters are increasingly used to identify either low-flow status or anaerobic metabolism in shock resuscitation. However, the performance of CO2-derived parameters in cardiac surgical patients is poorly understood...

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A High-Fidelity Percutaneous Model Used to Demonstrate ECMO Cannulation

Abstract Medical simulation provides a realistic environment for practitioners to experience a planned clinical event in a controlled educational setting. We established a simulation model composed of synthetic ballistic gelatin..

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Clinical risk score for postoperative pneumonia following heart valve surgery

Abstract Background:  Postoperative pneumonia (POP) is one of the most common infections following heart valve surgery (HVS) and is associated with a significant increase in morbidity, mortality, and health care..

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Spectrum Medical Quantum or Terumo CDI 500: Which Device Measures Hemoglobin and Oxygen Saturation Most Accurately When Compared to a…

Abstract To examine the accuracy between analyzers, the Terumo CDI 500 and the Spectrum Medical Quantum were compared to each other and to the ABL90 FLEX benchtop blood analyzer. Patients..

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Current Application of NIRS and CPB Initiation Times in German Cardiac Surgery Centers: A Survey

Abstract Near-infrared spectroscopy (NIRS) has been widely used in cardiac surgery to monitor cerebral oxygen supply. The initiation and perioperative management of cardiopulmonary bypass (CPB) constitute critical events in modifying..

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The multivariable prognostic models for severe complications after heart valve surgery

Abstract Background To provide multivariable prognostic models for severe complications prediction after heart valve surgery, including low cardiac output syndrome (LCOS), acute kidney injury requiring hemodialysis (AKI-rH) and multiple organ..

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Extracorporeal Life Support and Cardio-Pulmonary Bypass for Central Airway Surgery: A Systematic Review

Abstract Background Major airway surgery can pose a complex problem to perioperative central airway management. Adjuncts to advanced ventilation strategies have included cardiopulmonary bypass (CPB), veno-arterial (VA-ECLS) or veno-venous extracorporeal..

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Fluid resuscitation after cardiac surgery in the intensive care unit: A bi-national survey of clinician practice. (The FRACS-ICU clinician survey)

Abstract Context and Aims: To describe current fluid and vasopressor practices after cardiac surgery in Australia and New Zealand cardiothoracic intensive care units (ICU).  Design and Setting: This web-based survey was conducted..

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Renal function and inflammatory response in neonates undergoing cardiac surgery with or without antegrade cerebral perfusion—a post hoc analysis

Abstract Background: Cardiopulmonary bypass (CPB) may lead to tissue hypoxia, inflammatory response, and risk for acute kidney injury (AKI). We evaluated the prevalence of AKI and inflammatory response in neonates undergoing..

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Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

Abstract Introduction: Many donor organs contain significant leukocyte reservoirs which upon transplantation activate recipient leukocytes to initiate acute rejection. We aimed to assess whether non-ischemic heart preservation via ex vivo perfusion promotes immunodepletion..

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Effect of Cardiac Surgery on One-Year Patient-Reported Outcomes: A Prospective Cohort Study

Abstract Background Current cardiac surgery risk algorithms and quality measures focus on perioperative outcomes. However, delivering high-value, patient-centered cardiac care will require a better understanding of long-term patient-reported quality of..

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Direct Versus Side Graft Cannulation From the Right Axillary Artery in Thoracic Aortic Surgery

Abstract Background The  can be cannulated for antegrade  directly or by employing a prosthetic  anastomosed to the artery. Methods From 2008 until 2019, 688 patients underwent axillary artery . Of those, 287 underwent direct..

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