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A prospective randomized study of a modified technique of ultrafiltration during pediatric open-heart surgery

Abstract Conventional ultrafiltration (UF) fails to reverse satisfactorily hemodilution and the rise in total body water (TBW) seen after cardiopulmonary bypass (CPB). We have modified the technique, timing, and placement..

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Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation

Abstract Previous studies suggested that contact pathway factors drive thrombosis in mechanical circulation. We used a rabbit model of veno-arterial extracorporeal circulation (VA-ECMO) to evaluate the role of factors XI..

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Modified ultrafiltration in surgical correction of congenital heart disease with cardiopulmonary bypass

Abstract The surgical correction of congenital heart disease using haemodilution and hypothermia with cardiopulmonary bypass (CPB) may expose patients to tissue ischaemia and initiate a systemic inflammatory response, increasing the..

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Surgical Maneuver for Ventricular Septal Defect Exposure During Congenital Heart Surgery Through the Right Axillary Transverse Minithoracotomy

Abstract Right axillary transverse minithoracotomy is not conventionally used for ventricular septal defect (VSD) repair because of complicated VSD exposure and the need for a temporary tricuspid valve leaflet detachment..

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EchoGuide™

NOW AVAILABLE! Download ASE’s EchoGuideTM today and gain access to a powerful echocardiography calculator and algorithm app. EchoGuideTM provides access to over 50 calculators, algorithms, and charts based on key ASE guidelines..

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Cor Triatriatum Sinister (Andrei Satsuk)

The cor triatriatum sinister is a rare congenital heart defect, the product of an embryonic defect in the incorporation of the common pulmonary vein to the left atrium, this being..

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Heparin Resistance During Cardiopulmonary Bypass in Adult Cardiac Surgery

Abstract The use of heparin for anticoagulation has changed the face of cardiac surgery by allowing a bloodless and motionless surgical field throughout the introduction of cardiopulmonary bypass (CPB). However,..

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A successful modification of ultrafiltration for cardiopulmonary bypass in children

Abstract Total body water (TBW) is increased after cardiopulmonary bypass (CPB) resulting in tissue oedema and organ dysfunction. Ultrafiltration has been used to reduce this accumulation of water, although conventional..

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The cost of blood: a study of the total cost of red blood cell transfusion in patients with β-thalassemia using…

Abstract BACKGROUND To accurately quantify the costs of care for patients with transfusion-dependent thalassemia (TDT), and to evaluate cost-effectiveness of new treatments, data are required on costs of regular red..

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Cardiac surgery with cardiopulmonary bypass markedly lowers SARS-COV-2 antibody titer

Abstract Background This study aims to investigate the effect of cardiopulmonary bypass on antibody titers in patients vaccinated against the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) undergoing cardiac surgery with..

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Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study

Abstract Background In patients receiving venovenous (VV)  (ECMO) packed red blood cell (PRBC) transfusion thresholds are usually higher than in other patients who are critically ill. Available guidelines suggest a restrictive..

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CytoSorb hemoadsorption for removal of apixaban – a proof-of-concept pilot case for a randomized controlled trial

This case reports on an 81-year-old man who presented to the hospital with methicillin-sensitive Staphylococcus aureus prosthetic aortic valve endocarditis and hemodynamic instability requiring an urgent operation (EuroSCORE II 31.05%)..

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Citrate does not change viscoelastic haemostatic assays after cardiopulmonary bypass

Abstract Context: Viscoelastic hemostatic assays (VHA) are commonly used to identify specific cellular and humoral causes for bleeding in cardiac surgery patients. Cardiopulmonary bypass (CPB) alterations to coagulation are observable on..

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Assessing the Sensitivity of Multi-Distance Hyperspectral NIRS to Changes in the Oxidation State of Cytochrome C Oxidase in the Brain

Abstract Near-infrared spectroscopy (NIRS) measurements of tissue oxygen saturation (StO2) are frequently used during vascular and cardiac surgeries as a non-invasive means of assessing brain health; however, signal contamination from..

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Effects of recombinant erythropoietin on hemoglobin levels and blood transfusion needs in patients with preoperative anemia undergoing cardiac surgery

Abstract Introduction: Preoperative anemia is an important and relatively common problem in patients undergoing cardiac surgery, and its treatment is crucial in improving postoperative outcomes. The use of recombinant erythropoietin is..

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Comparison of Bivalirudin Versus Heparin for Anticoagulation During Extracorporeal Membrane Oxygenation

Abstract The effect and safety of bivalirudin compared with heparin in patients undergoing extracorporeal membrane oxygenation (ECMO) remains unclear. Therefore, we conducted a systematic review and meta-analysis to compare the effectiveness and..

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Platelet preservation in cardiac surgery using minimally invasive extracorporeal circulation versus optimized cardiopulmonary bypass

Abstract Background Minimally invasive extracorporeal circulation (MiECC) is employed as a strategy to attenuate the physiologic disturbance caused by cardiopulmonary bypass. The aim of this study was to compare the..

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A Novel Anticoagulation Method Based on Electrochemical Characteristics of Blood: An in vitro Study

Abstract This in vitro experimental investigation aimed to provide a novel method for preventing blood clotting based on the electrochemical characteristics of blood. Using this method in cases such as..

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Right Ventricular Injury Increases Mortality in Patients with Acute Respiratory Distress Syndrome on Veno-Venous Extracorporeal Membrane Oxygenation: A Systematic Review…

Abstract Right ventricular injury (RVI) in the context of acute respiratory distress syndrome (ARDS) is well recognized as an important determinant risk factor of mortality. Veno-venous extracorporeal membrane oxygenation (VV-ECMO)..

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Unilateral Left Lung Agenesis Associated with Supracardiac Total Anomalous Pulmonary Venous Connection

Abstract Congenital pulmonary anomalies are rare and can vary in their presentation. Unilateral lung agenesis implies absence of lungs and lung blood vessels, whereas the principal bronchus can be absent..

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American Society of ExtraCorporeal Technology Standards and Guidelines for Pediatric and Congenital Perfusion Practice

Abstract The American Society of ExtraCorporeal Technology (AmSECT) has created the following document based on clinical evidence and currently accepted perfusion practices. Perfusionists are the only allied healthcare professionals formally..

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Propofol versus insulin cardioplegia in valvular heart surgeries assessed by myocardial histopathology and troponin I

Abstract Background and Aims Despite of the effectiveness of on pump cardiac surgeries in valvular diseases, cardioplegic arrest and myocardial reperfusion injury are still an obstacle. Many cardioprotective additives are..

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Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants

Abstract Electroencephalogram (EEG) approaches may provide important information about developmental changes in brain-state dynamics during general anesthesia. We used multi-electrode EEG, analyzed with multitaper spectral methods and video recording of..

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Extracorporeal Membrane Oxygenation Support in COVID-19 Patients: A Propensity Score Analysis

Abstract Revised guidelines clarify indications for extracorporeal membrane oxygenation (ECMO) support in Coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome (ARDS). Limited data exist to compare clinical outcomes..

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Atrial Functional Mitral Regurgitation: A JACC: Cardiovascular Imaging Expert Panel Viewpoint

Abstract Functional or secondary mitral regurgitation (MR) is associated with increased cardiovascular morbidity and mortality. Mechanistically, secondary MR is attributable to an imbalance between mitral leaflet tethering and closure forces,..

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Initial Thoracic Endovascular Aortic Repair vs Medical Therapy for Acute Uncomplicated Type B Aortic Dissection

Abstract Importance  Thoracic endovascular aortic repair (TEVAR) has increasingly been used for uncomplicated type B aortic dissection (uTBAD) despite limited supporting data. Objective  To assess whether initial TEVAR following uTBAD is associated..

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Management algorithms and artificial intelligence systems for cardiopulmonary bypass

Abstract This article introduces management algorithms to support operators in choosing the best strategy for metabolic management during cardiopulmonary bypass using artificial intelligence systems. We developed algorithms for the identification..

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