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Swine intestinal segment perfusion model for the evaluation of nutrients bioaccessibility

Abstract Nutrition science requires more science-based evidences for the development of effective functional diets. To reduce animals for experimental purposes innovative reliable and informative models, simulating the complex intestinal physiology,..

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Impact of Steroid on Macrophage Migration Inhibitory Factor During and After Cardiopulmonary Bypass

Abstract Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine released in response to glucocorticoids, which counter-regulates the effects of glucocorticoids. This study was performed to determine the impact of steroids..

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Association of postoperative atrial fibrillation with higher dosing ratios of protamine-to-heparin

Abstract Background: Postoperative atrial fibrillation (POAF) is defined as new-onset AF in the immediate postoperative period. The relatively high incidence of POAF after cardiac surgery is well described, but pathophysiological..

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Minimally Invasive versus Conventional Aortic Root Surgery: Results of an Intermediate-Volume Center

Abstract Background  We evaluate the outcome of aortic root surgery via an upper J-shaped mini-sternotomy (MS) versus full sternotomy (FS) in an intermediate-volume center. Methods  Between November 2011 and February 2019,..

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Partial aortic arch replacement without circulatory arrest: A case study

Abstract Hypothermic circulatory arrest is commonly used during aortic arch surgery. However, it is associated with high risk of visceral organ and lower limb ischemia. There may be advantages to..

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Verticalization Therapy for Acute Respiratory Distress Syndrome Patients Receiving Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone positioning is an..

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Safety of bloodless open-heart surgery on cardiopulmonary bypass in selected children: A single center experience with minimal invasive extracorporeal circulation

Abstract Introduction Bloodless cardiac surgery refers to open-heart surgery without blood or blood products. The cardiopulmonary bypass (CPB) circuits are primed with crystalloid solely, and there is no intraoperative blood..

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Hyperkalemic or Low Potassium Cardioplegia Protects against Reduction of Energy Metabolism by Oxidative Stress

Abstract Open-heart surgery is often an unavoidable option for the treatment of cardiovascular disease and prevention of cardiomyopathy. Cardiopulmonary bypass surgery requires manipulating cardiac contractile function via the perfusion of..

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Adult Clinical Perfusion Practice Survey: 2020 results

Abstract Background: Cardiovascular perfusion is a dynamic healthcare profession where new practices are frequently introduced. Despite the emergence of evidence-based clinical practice guidelines, little is known about their dissemination at..

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The healthy heart does not control a specific cardiac output: a plea for a new interpretation of normal cardiac function

Abstract The current evidence suggests that the healthy heart does not sense the optimal cardiac output (Q̇) because the different organ systems that influence cardiac function do not interact to..

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Parallel Venovenous Extracorporeal Membrane Oxygenation Circuits for Refractory Hypoxemia in a Super-Super-Obese Patient

Abstract VENOVENOUS EXTRACORPOREAL MEMBRANE OXYGENATION (VV ECMO) represents a rescue form of life support for refractory respiratory failure, shown to confer a mortality benefit.  Although relative contraindications to VV ECMO..

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Assessing Risk Factors for Prolonged Intensive Care Unit Stay After Surgery for Adult Congenital Heart Disease: A Study From a…

Abstract Background Prolonged post-surgery intensive care unit (ICU) stay for congenital heart disease (CHD) has been explored in the pediatric population. However, there is limited data for adult CHD (ACHD),..

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Fibrinogen is an independent preoperative predictor of hospital length of stay among patients undergoing coronary artery bypass grafting

Abstract Objective This study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and hospital length of stay (LOS) of patients undergoing Coronary Artery Bypass Grafting..

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ECMO-CENTRAL Pediatric adverse events

 Introduction ECMO-CENTRAL Background & Methodology - Peta Alexander & Ryan Barbaro 10:20 Acute Kidney Injury - Steven Gorga 10:30 Hemolysis - Francesca Sperotto 10:40 Infection Adverse Events - Elise Emrath..

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The 2023 International Society for Heart and Lung Transplantation Guidelines for Mechanical Circulatory Support: A 10- Year Update

Abstract In 2013, the International Society for Heart and Lung Transplantation (ISHLT) published the first official guidelines for implantable mechanical circulatory support (MCS) as commissioned by its Board of Directory...

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Sustaining Life versus Altering Life-Saving Drugs: Insights to Explain the Paradoxical Effect of Extracorporeal Membrane Oxygenation on Drugs

Abstract There has been a substantial increase in the use of extracorporeal membrane oxygenation (ECMO) support in critically ill adults. Understanding the complex changes that could affect drugs’ pharmacokinetics (PK)..

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Comparison of anticoagulation monitoring strategies for adults supported on extracorporeal membrane oxygenation: A systematic review

Abstract Background Anticoagulation is critical in patients supported on extracorporeal membrane oxygenation (ECMO). The appropriate monitoring strategies for heparin remain unclear. Objectives This systematic review aimed to compare the accuracy..

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Early Tracheostomy During Extracorporeal Membrane Oxygenation: The Question Is Not When But Who

Abstract Boudreaux et al. are to be commended for their publication in this month’s ASAIO regarding the utility of early tracheostomy in 150 patients placed on venovenous (VV) extracorporeal membrane oxygenation (ECMO) for respiratory failure. Thirty-five of the..

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Central Versus Peripheral Arterial Pressure Monitoring in Patients Undergoing Cardiac Surgery: A Prospective Observational Study

Abstract Objective The aortic-to-radial arterial pressure gradient is described during and after cardiopulmonary bypass (CPB), and can lead to underestimating arterial blood pressure. The authors hypothesized that central arterial pressure..

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Large volume acute normovolemic hemodilution in patients undergoing cardiac surgery with intermediate-high risk of transfusion: A randomized controlled trial

Abstract Study Objective: To investigate whether large volume acute normovolemic  (L-ANH), compared with moderate acute normovolemic  (M-ANH), can reduce perioperative allogeneic   with intermediate-high risk of transfusion during cardiac surgery with  (CPB). Design: Prospective . Setting:..

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Mitral valve replacement & LAA closure & AF

Patient with severe MS and MR and AF and LAA undergone new technique of MVR as well as LAA closure and Aortopulmonary separation and Bovine Pericardial Patch insertion for impediment..

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RA clot and TV repair

Patient with RA clot and TV repair without usage of CPB neither hep and completely beating with choking.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as..

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Extensive resection and LA roof reconstruction

LA Sarcoma Extension from LT and RT lung undergone extensive resection and LA roof reconstruction with bovine pericardial patch.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center..

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LV aneurysmectomy and PMA and LV reconstruction

Patient with LV pseudo aneurysm and severe MR and and clot within pericardial space undergone LV aneurysmectomy and PMA and LV reconstruction.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical..

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Chemo tx with fistula to LA and pericardial space

Patient with SCC of upper third esophagus and undergone chemo tx with fistula to LA and pericardial space.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as..

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Reconstruction annulus and MVR and pulmonary vein rerouting

Patient with severe bacterial endocarditis and mobile vegetation on mitral valve and annamalous inferior pulmonary vein undergone reconstruction annulus and MVR and pulmonary vein rerouting.  Dr.Sam Zeraatian Nejad Davani, CEO..

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CABG and SVR and IABPC

Patient with LVEF 10 percent and 3VD and DOE undergone CABG and SVR and IABPC.  Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as well as Head..

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Hemodynamic and recirculation performance of dual lumen cannulas for venovenous extracorporeal membrane oxygenation

Abstract Venovenous extracorporeal membrane oxygenation (ECMO) can be performed with two single lumen cannulas (SLCs) or one dual-lumen cannula (DLC) where low recirculation fraction (Rf) is a key performance criterion...

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Bacteria in Extracorporeal Membrane Oxygenation Circuit Clots of a Patient With Persistent Bacteremia: A Case Report

Abstract A neonate with pulmonary hypertension was supported with extracorporeal membrane oxygenation (ECMO). During ECMO support, the patient developed Enterococcus faecalis bacteremia, treated with targeted antibiotics. Despite the maximum dose of antibiotics, routine blood..

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A report of the first pediatric heart transplant following donation after circulatory death in the United States using ex-vivo perfusion

Abstract Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients. We..

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