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Clinical decision support for ExtraCorporeal Membrane Oxygenation: Will we fly by wire?

Abstract Prognostic modelling techniques have rapidly evolved over the past decade and may greatly benefit patients supported with ExtraCorporeal Membrane Oxygenation (ECMO). Epidemiological and computational physiological approaches aim to provide..

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The ProtekDuo® Cannula for Acute Mechanical Circulatory Support

Abstract The ProtekDuo® is a dual lumen cannula that can be used in numerous configurations to treat cardiogenic shock and hypotension. Its default function is as a temporary percutaneous right..

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Minimized Hemodiafiltration for Extracorporeal Membrane Oxygenation in Infants

Abstract Background  Fluid overload is a serious complication in the treatment of infants with extracorporeal membrane oxygenation (ECMO). Volume overload leads to prolonged ECMO therapy if left untreated. The renal..

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ECMOLIFE intra-hospital transport in life-saving for pulmonary vein obstruction

Abstract Background Transport with extracorporeal membrane oxygenation (ECMO) in the hospital setting can become a challenge as well as in the out-of-hospital setting. In particular, the management of intra-hospital transport..

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Hypoxic-Ischemic Brain Injury in ECMO: Pathophysiology, Neuromonitoring, and Therapeutic Opportunities

Abstract Extracorporeal membrane oxygenation (ECMO), in conjunction with its life-saving benefits, carries a significant risk of acute brain injury (ABI). Hypoxic-ischemic brain injury (HIBI) is one of the most common..

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Extracorporeal hemoadsorption in critically ill COVID-19 patients on VV ECMO: the CytoSorb therapy in COVID-19 (CTC) registry

Abstract Objectives: The CytoSorb therapy in COVID-19 (CTC) registry evaluated the clinical performance and treatment parameters of extracorporeal hemoadsorption integrated with veno-venous extracorporeal membrane oxygenation (VV ECMO) in critically ill COVID-19..

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Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry

Abstract Background: Acute myocarditis can result in severe hemodynamic compromise requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Outcomes and factors associated with mortality among myocarditis patients are not well described in..

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Why is it beneficial to use CytoSorb® during Heart Transplantation? – Results of a recent RCT

Description Brand new data and publications - introduced and discussed by the author: Assoc. Prof. Endre Németh, Semmelweis University Budapest Moderation: Dr. Marijana Matejic-Spasic, CytoSorbents Europe GmbH  

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Improving Patient Blood Management Programs: An Implementation Science Approach

Abstract Organized patient blood management (PBM) programs function in numerous hospitals and health systems around the world contributing to improved patient outcomes as well as increased patient engagement, decreased resource..

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A norepinephrine weaning strategy using dynamic arterial elastance is associated with reduction of acute kidney injury in patients with vasoplegia…

Abstract Study objective To evaluate the impact of a dynamic arterial elastance guided  weaning strategy on the occurrence of  (AKI) in  with  after cardiac surgery. Design A post-hoc analysis of a monocentric . Setting A..

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Sodium citrate effectively used in shed mediastinal blood autotransfusion after cardiac surgery

Abstract Background We used sodium citrate as an alternative anticoagulation agent to heparin in the procedure of autologous blood transfusion with patients with postoperative haemorrhage after CPB. The aim of..

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Longitudinal assessment of cerebral blood volume variation in human neonates using ultrafast power Doppler and diverging waves

Abstract Longitudinal assessment of brain perfusion is a critical parameter for neurodevelopmental outcome of neonates undergoing cardiopulmonary bypass procedure. In this study, we aim to measure the variations of cerebral..

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Considerations for integrating wearables into the everyday healthcare practice

Abstract Wearable technologies are becoming ever more popular as suggested tools for use in modern medicine. Studies evidence their growing pragmatism and provision of objective data for a more informative..

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The role and timing of cardiopulmonary bypass in the surgical repair of traumatic cardiac injury

Abstract Objectives The management of traumatic cardiac injury (TCI) may require a prompt treatment, including the use of cardiopulmonary bypass (CPB) followed by surgical repair. This study evaluated the surgical..

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Comparison of Prothrombin Complex Concentrate with Activated Factor VII Use for Bleeding Following Cardiopulmonary Bypass in Children

Abstract Objective This study aims to compare the efficacy and safety of activated recombinant factor VII (rFVIIa) and prothrombin complex concentrate (PCC) in the treatment of bleeding complications following surgery..

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Vasoplegic syndrome in cardiovascular surgery; evaluating effects of Sevoflurane and Glibenclamide in a porcine model

Abstract Background Vasoplegic syndrome is frequently observed during cardiac surgery and resembles a complication of high mortality and morbidity. There is a clinical need for therapy and prevention of vasoplegic syndrome..

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Patient, Clinician, and Institution level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis

Abstract Background Conflicting evidence exists regarding the risks and benefits of inotropic therapies during cardiac surgery, and the extent of variation in clinical practice remains understudied. Therefore, the authors sought..

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Evaluation of Latex Immunoturbidimetric Assay Thresholds and HIT in Cardiothoracic Surgery

Abstract Background Heparin-induced thrombocytopenia (HIT) is a common differential diagnosis in cardiothoracic surgery. The latex immunoturbidimetric assay (LIA) is an enhanced immunoassay that has recently been introduced for the detection..

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3 myths about ECMO that are costing hospitals and patients

Abstract Although the global pandemic is officially over, it has left a permanent mark on the health care landscape, reshaping the dynamics of hospitals in the United States. While staffing..

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Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes

Abstract Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms remain largely unknown. Here, we systematically investigate the major cellular pathways affected by excess molecular..

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What is the potential benefit of pre-hospital extracorporeal cardiopulmonary resuscitation for patients with an out-of-hospital cardiac arrest? A predictive modelling…

Abstract Aim In this  study we aimed to investigate how many  with an out-of-hospital cardiac arrest (OHCA) would benefit from pre-hospital as opposed to in-hospital initiation of  cardiopulmonary resuscitation (ECPR). Methods A  of Utstein..

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Blood versus crystalloid cardioplegia during triple valve surgery: A single center experience

Abstract Background The efficacy of different cardioplegia solutions on outcomes of complex cardiac operations such as triple valve surgery (TVS) is scarce. Here we compared the outcomes in TVS patients..

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Preceding Clinical Events in High-risk, Postoperative, Pediatric Cardiac Patients—A Novel Association With Bacteremia

Abstract Objective: Blood stream infections (BSIs) are well described in pediatric cardiac intensive care units (PCICU). We noted that postoperative high-risk patients may develop BSI after a preceding clinical event (PCE)...

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HTK-N Versus Del Nido Cardioplegia for Hypothermic Machine Perfusion of Donation after Circulatory Death Hearts: Comparison of Left-Ventricular Contractility and…

Abstract Purpose Del Nido cardioplegia (dNC) is a 1:4 formula of blood:crystalloid and contains erythrocytes as oxygen carriers. Hearts donated after circulatory death (DCD) are maintained by ex-vivo machine perfusion..

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In vitro study on the effect of fibrinogen γ-chain peptide-coated ADP-encapsulated liposomes on postcardiopulmonary bypass coagulopathy using patient blood

Abstract Background Fibrinogen γ-chain peptide-coated, adenosine 5'-diphosphate (ADP)-encapsulated liposomes (H12-ADP-liposomes) are potent hemostatic adjuvants that promote platelet thrombi formation at bleeding sites. Although we have reported the efficacy of these..

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Predictors of early mobilization in patients requiring VV ECMO for greater than 7 days: An international cohort study

Abstract Background Despite the demonstrated benefits of rehabilitation, active physical therapy and early mobilization are not universally performed during critical illness, especially among patients receiving extracorporeal membrane oxygenation (ECMO), with..

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ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

Abstract The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is..

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Step by step daily management of short-term mechanical circulatory support for cardiogenic shock in adults in the intensive cardiac care…

Step by step daily management of short-term mechanical circulatory support for cardiogenic shock in adults in the intensive cardiac care unit. A clinical consensus statement of the Association for Acute..

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Update on CytoSorb® in Infective Endocarditis

Update on CytoSorb® in Infective Endocarditis and other cardiovascular indications. Prof. Daniel Wendt, Essen/German

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Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update

Abstract The impact of vaccination and new SARS-CoV-2 variants on peri-operative outcomes is unclear. We aimed to update previously published consensus recommendations on timing of elective surgery after SARS-CoV-2 infection..

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