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Individualized heparin monitoring and management reduces protamine requirements in cardiac surgery on minimal invasive extracorporeal circulation; A prospective randomized study

Abstract Introduction Individualized heparin and protamine management is increasingly used as a strategy to reduce coagulation activation and bleeding complications. While it is associated with increased heparin requirements during Cardiopulmonary..

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Phosphodiesterases in heart and vessels- From Physiology to Diseases

Abstract Phosphodiesterases (PDEs) are a superfamily of enzymes that hydrolyze cyclic nucleotides, including cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), critical secondary messengers in the neurohormonal regulation in..

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Determining sex-specific preoperative haemoglobin levels associated with intraoperative red blood cell transfusion in cardiac surgery: a retrospective cohort study

Abstract Background Anaemic cardiac surgery patients are at greater risk of intraoperative red blood cell transfusion. This study questions the application of the World Health Organization population-based anaemia thresholds (haemoglobin..

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Extracorporeal Circulation and Venous Hemodynamics: A Literature Review on Physiological Foundations to Clinical Applications

Abstract The venous system constitutes a vital component of the human circulatory system, facilitating the return of deoxygenated blood from tissues and organs back to the heart. During cardiac surgeries..

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Evaluating the Impact of Operative Team Familiarity on Cardiac Surgery Outcomes

Abstract Objective:  To associate surgeon-anesthesiologist team familiarity with cardiac surgery outcomes. Background:  Team Familiarity (TF), a measure of repeated team member collaborations, has been associated with improved operative efficiency; however,..

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Performance Evaluation of Geometrically Different Pediatric Arterial Cannulae in a Pediatric Cardiopulmonary Bypass Model

Abstract Objective: To define a reference chart comparing pressure drop vs. flow generated by a set of arterial cannulae currently utilized in cardiopulmonary bypass conditions in pediatric surgery. Methods: Cannulae from two..

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Preoperative Sildenafil in Pediatric Patients Undergoing Congenital Heart Surgeries: A Systematic Review and Meta-Analysis

Abstract Background.  Pulmonary hypertension (PH) is a common complication of congenital heart disease (CHD). With early surgical intervention, outcomes have improved over the last two decades. Persistent PH, however, may..

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Do we correctly calculate doses of cardioplegia during aortic valve replacement procedures? A preliminary report

Abstract Introduction Intraoperative myocardial protection during aortic valve replacement (AVR) for aortic stenosis (AS) is of paramount importance for outcomes. The dose of cardioplegia is usually calculated with reference to body mass. Aim..

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Safety and Efficacy of Extracorporeal Membrane Oxygenation Heating Units

Abstract Background Patient temperature during extracorporeal membrane oxygenation (ECMO) is commonly managed by dedicated heating units (HUs) that are integrated into ECMO circuitry. Currently, no HU has received approval for..

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In vitro evaluation of the performance of an oxygenator depending on the non-standard gas content of the inlet blood with…

Abstract Introduction The performance of an oxygenator, as found in literature, is evaluated according to protocols that define standard values of the gas content in the inlet blood. However, when..

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Predicting pediatric cardiac surgery-associated acute kidney injury using machine learning

Abstract Background Prediction of cardiac surgery-associated acute kidney injury (CS-AKI) in pediatric patients is crucial to improve outcomes and guide clinical decision-making. This study aimed to develop a supervised machine..

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Safety and Efficacy of Albumin for Pump Priming in Cardiac Surgery: A Meta-Analysis

Abstract Objectives To assess the efficacy and safety of albumin as pump priming fluid in cardiac surgery. Design Meta-analysis of randomized controlled trials. Setting Each study was conducted in a..

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Left ventricular hemodynamics with veno-arterial extracorporeal membrane oxygenation

Abstract Background There is considerable debate about the hemodynamic effects of veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Aims To evaluate the changes in left ventricular (LV) function, volumes, and work in..

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Can machine learning provide preoperative predictions of biological hemostasis after extracorporeal circulation for cardiac surgery?

Abstract Objectives The goal of this study was to improve decision making regarding the transfusion of patients at the end of extracorporeal circulation for cardiac surgery through machine learning predictions..

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Protecting the Brain While Healing Hearts: The Protective Role of Cognitive Reserve in Cardiac Surgery

Abstract Objective One of the most significant complications following coronary artery bypass grafting (CABG) is postoperative cognitive decline (POCD). CABG patients frequently experience considerable postoperative cognitive dysfunction (POCD), including decline..

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Nursing Management of Patients Requiring Acute Mechanical Circulatory Support Devices

Abstract Topic The growing use of acute mechanical circulatory support devices to provide hemodynamic support that has accompanied the increasing prevalence of heart failure and cardiogenic shock, despite significant improvement..

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Flow-controlled versus pressure-controlled ventilation in cardiac surgery with cardiopulmonary bypass – A single-center, prospective, randomized, controlled trial

Abstract Study objective Multifactorial comparison of flow-controlled ventilation (FCV) to standard of pressure-controlled ventilation (PCV) in terms of oxygenation in cardiac surgery patients after chest closure. Design Prospective, non-blinded, randomized,..

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Achieving a preoperative haemoglobin above 130 g L-1 may be more important in female than in male patients before cardiac…

Abstract Sex-specific preoperative haemoglobin levels and the need for perioperative red cell transfusion in men and women are still debated. Cavalli and colleagues examined the appropriateness of World Health Organization..

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The state of emergency department extracorporeal cardiopulmonary resuscitation: Where are we now, and where are we going?

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged in the context of the emergency department as a life-saving therapy for patients with refractory cardiac arrest. This review examines the utility of..

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Timing of Initiation of Extracorporeal Membrane Oxygenation Support and Outcomes Among Patients With Cardiogenic Shock

Abstract Background Venoarterial extracorporeal membrane oxygenation (ECMO) provides full hemodynamic support for patients with cardiogenic shock, but optimal timing of ECMO initiation remains uncertain. We sought to determine whether earlier..

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Venopulmonary Artery Extracorporeal Life Support (VPa ECMO): A Novel Strategy for Refractory Hypoxemia Complicating VV ECMO

Abstract Refractory hypoxemia (RH) during venovenous extracorporeal membrane oxygenation (VV ECMO) support is a complex problem that limits the benefit of this therapy. The need for sustained deep sedation and..

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Máster de Formación Permanente de Práctica Clínica Avanzada en Circulación Extracorpórea y Perfusión - UAM Madrid

Máster de 120 ECTS se presenta como oferta académica actualizada e interdisciplinar con un potente contenido de materias fundamentales, procedimentales y de especialización, y una perspectiva única sobre la capacitación..

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European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post‑resuscitation care

Abstract The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the..

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The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations

Abstract Purpose: The 2021 guidelines endorsed by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) recommend using highly malignant electroencephalogram (EEG) patterns (HMEP; suppression..

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Use of point‑of‑care ultrasound (POCUS) to monitor neonatal and pediatric extracorporeal life support

Abstract Extracorporeal membrane oxygenation (ECMO) is an invasive life support technique that requires a blood pump, an artificial membrane lung, and vascular cannulae to drain de-oxygenated blood, remove carbon dioxide,..

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Systemic Hemodynamics, Cardiac Mechanics, and Signaling Pathways Induced by Extracorporeal Membrane Oxygenation in a Cardiogenic Shock Model

Abstract Peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly being used in patients suffering from refractory cardiogenic shock (CS). Although considered life-saving, peripheral VA-ECMO may also be responsible for intracardiac..

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Recombinant Activated Factor VII (rFVIIa) for Bleeding After Thoracic Aortic Surgery: A Scoping Review of Current Literature

Abstract Background Bleeding after surgery on the thoracic aorta is a frequent complication, and can be associated with a significant increase in morbidity and mortality. Recombinant activated factor VII (rFVIIa)..

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ECPR Survivor Estimates: A Simulation-Based Approach to Comparing ECPR Delivery Strategies

Abstract Objective: The number of out-of-hospital cardiac arrest (OHCA) patients who may benefit from prehospital extracorporeal cardiopulmonary resuscitation (ECPR) is yet to be elucidated. Patient eligibility is determined both by case..

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Noninvasive Ventilation Before Intubation and Mortality in Patients Receiving Extracorporeal Membrane Oxygenation for COVID-19: An Analysis of the Extracorporeal Life…

Abstract Bilevel-positive airway pressure (BiPAP) is a noninvasive respiratory support modality which reduces effort in patients with respiratory failure. However, it may increase tidal ventilation and transpulmonary pressure, potentially aggravating..

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The biological role and future therapeutic uses of nitric oxide in extracorporeal membrane oxygenation, a narrative review

Abstract Background Nitric oxide (NO) is a gas naturally produced by the human body that plays an important physiological role. Specifically, it binds guanylyl cyclase to induce smooth muscle relaxation...

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