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Can ChatGPT transform cardiac surgery and heart transplantation?

Abstract Artificial intelligence (AI) is a transformative technology with many benefits, but also risks when applied to healthcare and cardiac surgery in particular. Surgeons must be aware of AI and..

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Use of intraoperative haemoadsorption in patients undergoing heart transplantation: a proof-of-concept randomized trial

Abstract Aims The aim of this trial was to compare the clinical effects of intraoperative haemoadsorption versus standard care in patients undergoing orthotopic heart transplantation (OHT). Methods and results In..

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Initial experience and outcomes with a hybrid extracorporeal membrane oxygenation and cardiopulmonary bypass circuit for lung transplantation

Abstract Background The utilization of extracorporeal life support (ECLS) for intraoperative support during lung transplantation has increased over the past decade. Although veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has recently emerged..

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Heart Transplantation From DCD Donors in Australia: Lessons Learned From the First 74 Cases

Abstract Heart transplantation from donation after circulatory death (DCD) donors has the potential to substantially increase overall heart transplant activity. The aim of this report is to review the first..

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Percutaneous Venopulmonary Extracorporeal Membrane Oxygenation as Bridge to Lung Transplantation

Abstract Mechanical circulatory support (MCS) as a bridge to lung transplant is an infrequent but accepted pathway in patients who have refractory end-stage pulmonary failure. The American Association of Thoracic..

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Melody Valve Implantation in the Tricuspid Position After Pediatric Heart Transplantation—A Case Report

Abstract Tricuspid regurgitation (TR) is common after a heart transplant and is associated with worse clinical outcomes. The incidence ranges from 34% immediately after transplant to 20% by 10 years...

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An in vitro comparison of intra-operative isohemagglutinin and human leukocyte antigen removal techniques in pediatric heart transplantation

Abstract Background: Highly sensitized pediatric patients awaiting heart transplantation experience longer wait times and thus higher waitlist mortality. Similarly, children less than 2 years of age have increased waitlist times and..

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Assessment of the need for routine intraoperative cell salvage in liver transplantation

Abstract Purpose: This study aimed to assess the necessity of routine intraoperative cell salvage in liver transplantations. Methods: A total of 327 liver transplants performed between 2014 and 2016 was..

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Use of Subclavian Extracorporeal Carbon Dioxide Removal for COVID-19 Acute Respiratory Distress Syndrome as a Bridge to Lung Transplantation

Abstract Severe acute hypercapnia is independently associated with increased adverse effects and intensive care unit mortality in mechanically ventilated patients. During the severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic,..

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The Use of Impella 5.5 for Donor–Heart Hemodynamic Support in Heart Transplantation

Abstract Primary graft dysfunction is a feared complication and cause of mortality post–heart transplant. Primary graft dysfunction may require mechanical circulatory support, such as venoarterial extracorporeal membrane oxygenation, which carries..

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Use of Extracorporeal Membrane Oxygenation for Primary Graft Dysfunction After Cardiac Transplantation: Results of an A Priori Ventless Approach

Abstract Primary graft dysfunction (PGD) after cardiac transplantation is a devastating complication with increasing frequency lately in the setting of donation after circulatory death (DCD). Severe PGD is commonly treated..

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CytoSorb with Ex Vivo Organ Perfusion: Transforming the Future of Solid Organ Transplantation

Abstract PRINCETON, N.J., Sept. 11, 2023 (GLOBE NEWSWIRE) --   (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in intensive care and cardiac surgery using blood purification via its..

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Heart transplant patients from socioeconomically distressed communities face higher mortality, organ failure risk

Abstract People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared..

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A Paradigm Shift in Heart Preservation: Improved Post-transplant Outcomes in Recipients of Donor Hearts Preserved with the SherpaPak System

Abstract Traditional ice storage has been the historic standard for preserving donor’s hearts. However, this approach provides variability in cooling, increasing risks of freezing injury. To date, no preservation technology..

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Standard calculations guide

(Thanks to Navin Kumar for letting us share) Preface: Working as a perfusionist is a highly challenging and rewardingcareer path. The educational standards are high, and theprofession appeals to those..

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Rotational Thromboelastometry–Guided Use of Synthetic Blood Products in Cardiac Transplant Patients: A Retrospective Before-After Study

Abstract Objectives Viscoelastic  assays, such as rotational  (ROTEM), are used increasingly in cardiac surgery to guide transfusion decisions. After separation from  (CPB), achieving  rapidly is the main goal before chest closure. The authors hypothesized..

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Ambulation of Patients With In Situ Femoral Intraaortic Balloon Pump While Awaiting Heart Transplantation

Abstract With the implementation of the new allocation system in the United States on October 18, 2018, patients requiring temporary mechanical circulatory support (tMCS) have the highest priority, a shorter..

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Effects of adding the second drainage cannula in severely hypoxemic patients supported with VV ECMO due to COVID-19-associated ARDS

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a recognized method of support in patients with severe and refractory acute respiratory distress syndrome (ARDS) caused by SARS-CoV-2 infection. While veno-venous (VV)..

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Cytokine adsorption correlates with lower circulating nucleosomes and is associated with decreased primary graft dysfunction

Abstract Elevated levels of neutrophil extracellular traps (NETs) have been reported in primary graft dysfunction, making methods to reduce or remove them highly valuable. The mechanisms behind primary graft dysfunction..

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Extracorporeal Life Support for Cardiogenic Shock in Adult Congenital Heart Disease—An ELSO Registry Analysis

Abstract There are minimal data on the use of venoarterial extracorporeal membrane life support (VA-ECLS) in adult congenital heart disease (ACHD) patients presenting with cardiogenic shock (CS). This study sought..

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Bicaval dual-lumen cannula for venovenous extracorporeal membrane oxygenation: Avalon© cannula in childhood disease

Abstract Severe acute refractory respiratory failure is considered a life-threatening situation, with a high mortality of 40 to 60%. When conservative oxygenation methods fail, a lifesaving measure is the introduction..

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Extracorporeal cytokine adsorption reduces systemic cytokine storm and improves graft function in lung transplantation

Abstract Objectives Ischemia–reperfusion injury often coincides with a , which can result in  following . Our previous research has demonstrated  improvement by cytokine adsorption during ex vivo lung perfusion. The aim of this study was..

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Impact of the Pediatric ABO Policy Change on Listings, Transplants, and Outcomes for Children Younger Than 2 Years Listed for…

Abstract Background: We assessed the impact of the liberalized ABO pediatric policy change on candidate characteristics and outcomes for children undergoing heart transplant (HT). Methods and results: Children <2 years undergoing HT..

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Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History

Abstract Heart transplantation is considered the gold standard for the treatment of advanced end-stage heart failure. However, standard donors after brain death are decreasing, whereas patients on the heart transplant waitlist are..

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Contemporary practice and perception of autologous blood salvage in hepato-pancreatico-biliary operations: an international survey

Abstract Background This study aimed to assess contemporary knowledge, attitudes and behaviors around transfusion of intraoperative salvaged blood (sRBCt) during hepato-pancreatico-biliary (HPB) operations. Findings are meant to inform the design..

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Predictors of early mobilization in patients requiring VV ECMO for greater than 7 days: An international cohort study

Abstract Background Despite the demonstrated benefits of rehabilitation, active physical therapy and early mobilization are not universally performed during critical illness, especially among patients receiving extracorporeal membrane oxygenation (ECMO), with..

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Modifications to therapeutic plasma exchange to achieve rapid exchange on cardiopulmonary bypass prior to pediatric cardiac transplant

Abstract Background Cardiac transplants increasingly occur following placement of ventricular assist devices (VADs). A strong association exists between human leukocyte antigen (HLA) sensitization and VAD placement; however, desensitization protocols that..

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The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation

Abstract Objective The use of mechanical circulatory support (MCS) in lung transplantation has been steadily increasing over the prior decade, with evolving strategies for incorporating support in the preoperative, intraoperative,..

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Swine intestinal segment perfusion model for the evaluation of nutrients bioaccessibility

Abstract Nutrition science requires more science-based evidences for the development of effective functional diets. To reduce animals for experimental purposes innovative reliable and informative models, simulating the complex intestinal physiology,..

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A report of the first pediatric heart transplant following donation after circulatory death in the United States using ex-vivo perfusion

Abstract Cardiac donation after circulatory death (DCD) with ex-vivo perfusion (EVP) has the potential to greatly increase the donor pool, a benefit that can extend to selected pediatric patients. We..

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