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Percutaneous oxygenated right ventricular assist device for pulmonary embolism: A case series

Abstract Acute right ventricular (RV) failure following massive pulmonary embolism (PE) can have significant hemodynamic consequences and is the mode of death. Temporary mechanical circulatory support can provide tissue perfusion..

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Can VA-ECMO Be Used as an Adequate Treatment in Massive Pulmonary Embolism?

Abstract Introduction: Massive acute pulmonary embolism (MAPE) with obstructive cardiogenic shock is associated with a mortality rate of more than 50%. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used..

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Unloading the Left Ventricle in Venoarterial ECMO: In Whom, When, and How?

Abstract Venoarterial extracorporeal membrane oxygenation provides cardiorespiratory support to patients in cardiogenic shock. This comes at the cost of increased left ventricle (LV) afterload that can be partly ascribed to retrograde..

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Fibrin Sheath(s) During and After an ECMO Run: Be Suspicious!

Abstract A 28 year old lady experienced acute asthma exacerbation precipitated by the inhalation of a recreational drug (“Kobret”). She presented with ultra-severe hypercapnia and associated acidosis due to refractory..

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Central venoarterial extracorporeal membrane oxygenation as a bridge to recovery after pulmonary endarterectomy in patients with decompensated right heart failure

Abstract Introduction: Patients with chronic thromboembolic pulmonary hypertension (CTEPH) and decompensated right heart failure (DRHF) have worse outcomes after pulmonary endarterectomy (PEA). We reviewed the role of central veno-arterial extracorporeal membrane..

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Extracorporeal life support in pregnant and postpartum women with COVID-19-related acute respiratory distress syndrome

Abstract Objective: Extracorporeal membrane oxygenation (ECMO) is an intervention used for patients with acute respiratory distress syndrome (ARDS) from COVID-19 who have failed conventional ventilatory strategies. Very few studies have given..

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Antibiotics and ECMO in the Adult Population—Persistent Challenges and Practical Guides

Abstract Extracorporeal membrane oxygenation (ECMO) is an emerging treatment modality associated with a high frequency of antibiotic use. However, several covariables emerge during ECMO implementation, potentially jeopardizing the success of..

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Early rehabilitation and mobilisation of neonatal and paediatric extracorporeal membrane oxygenation patients: A UK and Ireland consensus document

Abstract Despite increasing early rehabilitation and mobilisation (ERM) in paediatric intensive care, current evidence for ERM of neonatal and paediatric patients receiving extracorporeal membrane oxygenation (ECMO) is limited. The proposed..

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Multilayer Scaling of a Biomimetic Microfluidic Oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) has been advancing rapidly due to a combination of rising rates of acute and chronic lung diseases as well as significant improvements in the safety..

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Prognosis of Venoarterial Extracorporeal Membrane Oxygenation in Mixed, Cardiogenic and Septic Shock

Abstract Mixed cardiogenic-septic shock (MS), defined as the combination of cardiogenic (CS) and septic (SS) shock, is often encountered in cardiac intensive care units. Herein, the authors compared the impact of..

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Determinants of long-term outcomes in patients with COVID-19 supported with ECMO

Abstract We read with great interest the EuroECMO-COVID study in The Lancet Respiratory Medicine. Roberto Lorusso and colleagues should be congratulated for this important research, which contributes to our understanding of the..

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Cerebrovascular Complications of COVID-19 on Venovenous Extracorporeal Membrane Oxygenation

Abstract Objectives:  Evidence of cerebrovascular complications in COVID-19 requiring venovenous extracorporeal membrane oxygenation (ECMO) is limited. Our study aims to characterize the prevalence and risk factors of stroke secondary to COVID-19 in patients on venovenous ECMO. Design:  We analyzed..

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The Relation between Obesity and Mortality in Postcardiotomy Veno-arterial Membrane Oxygenation

Abstract BACKGROUND Obesity is an important health problem in cardiac surgery and among patients requiring post-cardiotomy veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Still, it remains unclear whether these patients are..

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Haematological Trends and Transfusion during Adult Extracorporeal Membrane Oxygenation: A Single Centre Study

Abstract The temporal trends in haematological parameters and their associations with blood product transfusion requirements in patients supported with extracorporeal membrane oxygenation (ECMO) are poorly understood. We performed a retrospective..

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Adverse Outcomes Associated With Atrial Arrhythmias After Veno-Venous Extracorporeal Membrane Oxygenation

Abstract Veno-venous extracorporeal membrane oxygenation (VV ECMO) is used as a treatment modality in those who fail to respond to conventional care. Hypoxia and medications used in the intensive care unit..

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Risk factors for elective and emergency oxygenator exchanges during veno-venous extracorporeal membrane oxygenation

Abstract Background Despite systemic anticoagulation and antithrombotic surface coating, oxygenator dysfunction remains one of most common technical complications of Extracorporeal membrane oxygenation (ECMO). Several parameters have been associated with an..

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Venoarterial extracorporeal membrane oxygenation for “protected” catheter-based embolectomy in high-risk/massive pulmonary embolism

Abstract High-risk/massive pulmonary embolism (PE) has a high mortality rate, especially when cardiac arrest occurs. Venoarterial (V-A) extracorporeal membrane oxygenation (ECMO) can rapidly restore and maintain circulation while a decision..

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Surgical pulmonary embolectomy on VA-ECMO

Abstract Surgical pulmonary embolectomy is a procedure that is often used to rescue patients with massive pulmonary embolism (PE) and circulatory collapse that have failed or may not be ideal..

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Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs

Abstract Objectives:  Extracorporeal membrane oxygenation (ECMO) has been used successfully to support adults with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related cardiac or respiratory failure refractory to conventional therapies. Comprehensive..

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Life-threatening massive pulmonary embolism rescued by venoarterial-extracorporeal membrane oxygenation

Abstract Background Despite quick implementation of reperfusion therapies, a few patients with high-risk, acute, massive, pulmonary embolism (PE) remain highly hemodynamically unstable. Others have absolute contraindication to receive reperfusion therapies...

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A value-based approach to optimize red blood cell transfusion in patients receiving extracorporeal membrane oxygenation

Abstract Introduction The risk, cost, and adverse outcomes associated with packed red blood cell (RBC) transfusions in patients with cardiopulmonary failure requiring extracorporeal membrane oxygenation (ECMO) have raised concerns regarding..

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Mechanical Circulatory Support to Treat Pulmonary Embolism: Venoarterial Extracorporeal Membrane Oxygenation and Right Ventricular Assist Devices

Abstract Mechanical circulatory support may help patients with massive pulmonary embolism who are not candidates for systemic thrombolysis, pulmonary embolectomy, or catheter-directed therapy, or in whom these established interventions have..

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Preclinical Studies on Pulsatile Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Refractory cardiogenic shock is increasingly being treated with veno-arterial extracorporeal membrane oxygenation (V-A ECMO), without definitive proof of improved clinical outcomes. Recently, pulsatile V-A ECMO has been developed to address some of the..

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Mechanical life support algorithm for emergency management of patient receiving extracorporeal membrane oxygenation

Abstract Background There are limited practical advanced life support algorithms to aid teams in the management of cardiac arrest in patients on extracorporeal membrane oxygenation (ECMO). Methods In our specialist..

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Long-term ECMO, efficiency and performance of EUROSETS adult A.L.ONE ECMO oxygenator

Abstract Background The management of the oxygenator can be prolonged in the long-term procedures especially during extracorporeal membrane oxygenation (ECMO) for bridge to transplant or bridge to recovery. Long-term use..

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Antithrombin Replacement and Extracorporeal Membrane Oxygenation: The time is ripe for a Simpler Solution

Abstract The use of extracorporeal membrane oxygenation (ECMO) circuit obligates the administration of systemic anticoagulation to avoid patient and circuit thrombosis. Identifying an optimal approach for achievement of target pharmacologic..

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Venovenous extracorporeal membrane oxygenation promotes alveolar epithelial recovery by activating Hippo/YAP signaling after lung injury

Abstract Background The preferred configuration for bridging patients with respiratory failure while awaiting  is venovenous  (VV ECMO). However, the protective effect of VV ECMO on the lung, as well as the underlying..

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Physiological adaptations during weaning from veno‑venous extracorporeal membrane oxygenation

Abstract Veno-venous extracorporeal membrane oxygenation (V–V ECMO) has an established evidence base in acute respiratory distress syndrome (ARDS) and has seen exponential growth in its use over the past decades...

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‘Goal-directed extracorporeal circulation: transferring the knowledge and experience from daily cardiac surgery to extracorporeal membrane oxygenation’

Abstract Metabolism management plays an essential role in extracorporeal technologies. There are different metabolic management devices integrated to extracorporeal devices; the most commonly used and accepted metabolic target in adult..

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