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Thromboembolic Complications in Continuous Versus Interrupted Anticoagulation During Venovenous Extracorporeal Membrane Oxygenation: A Multicenter Study

Abstract OBJECTIVES:  Continuous, therapeutic anticoagulation is the standard of care for patients on extracorporeal membrane oxygenation (ECMO). The risks of hemorrhage exacerbated by anticoagulation must be weighed with the thrombotic..

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Nosocomial Infections in Adults Receiving Extracorporeal Membrane Oxygenation: A Review for Infectious Diseases Clinicians

Abstract Over the past 10 years, there has been a rapid expansion in the use of extracorporeal membrane oxygenation (ECMO) in the care of patients with refractory cardiac or respiratory..

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Clinical Use of Bedside Portable Ultra–Low-Field Brain Magnetic Resonance Imaging in Patients on Extracorporeal Membrane Oxygenation: Results From the Multicenter…

Abstract BACKGROUND: Early detection of acute brain injury (ABI) at the bedside is critical in improving survival for patients with extracorporeal membrane oxygenation (ECMO) support. We aimed to examine the..

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Iron deposition in infants undergoing ECMO: A retrospective analysis of Postmortem tissue samples

Abstract Background Infants undergoing ECMO may have elevated serum ferritin and iron levels, raising concerns about iron overload. Recent studies question the utility of these markers for acute vs. chronic..

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Randomized Clinical Trials on Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock: Why Are They All Negative?

Abstract Cardiogenic shock (CS) is one of the most challenging areas in cardiology, where hard evidence is often limited. Several factors contribute to this scarcity. Patients with CS are typically..

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Accidental Lumbar Vein Cannulation During Emergent Veno-Venous Extracorporeal Membrane Oxygenation Initiation: Case Report

Abstract A 31-year-old woman at 41 weeks gestation presented after a home-delivery attempt, resulting in an intrauterine fetal demise. A cesarean section revealed purulent amniotic fluid. The patient had a..

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Efficacy of a Single Day Extracorporeal Membrane Oxygenation Training Course for Critical Care Air Transport Team Eligible Personnel

Abstract Background Extracorporeal membrane oxygenation (ECMO) is an advanced medical technology that is used to treat respiratory and heart failure. The U.S. military has used ECMO in the care of..

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Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference

Abstract OBJECTIVES:  To identify and prioritize research questions for anticoagulation and hemostasis management of neonates and children supported with extracorporeal membrane oxygenation (ECMO) from the Pediatric ECMO Anticoagulation CollaborativE (PEACE)..

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Anticoagulant Medications: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference

Abstract OBJECTIVES:  To derive systematic-review informed, modified Delphi consensus regarding the medications used for anticoagulation for pediatric extracorporeal membrane oxygenation (ECMO) for the Pediatric ECMO Anticoagulation CollaborativE (PEACE). DATA SOURCES: ..

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Spinal Cord Infarction During Extracorporeal Membrane Oxygenation:A Case Series and Review of the Literature

Abstract Background:  Little is known about extracorporeal membrane oxygenation (ECMO)-related spinal cord infarction (SCI), and reports regarding this rare and catastrophic complication are rare. Here, we report two cases of..

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Assessing Venous Thrombotic Risks in Extracorporeal Membrane Oxygenation-Supported Patients: A Systematic Review and Meta-Analysis

Abstract This study investigates the prevalence and risk factors associated with venous thrombotic events in patients receiving (ECMO) support. Systematic review and meta-analysis of case-control and cohort studies. PubMed, Cochrane..

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Low Versus Standard Intensity Heparin Protocols in Adults Maintained on Extracorporeal Membrane Oxygenation: A Retrospective Cohort Study

Abstract Background:  Patients maintained on extracorporeal membrane oxygenation (ECMO) often require systemic anticoagulation to prevent circuit clotting and systemic thromboembolic complications. The optimal intensity of anticoagulation to balance the risk..

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The Ventilatory Ratio as a Predictor of Successful Weaning from a Veno-Venous Extracorporeal Membrane Oxygenator

Abstract Background:  Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a critical intervention for patients with severe lung failure, especially acute respiratory distress syndrome (ARDS). The weaning process from ECMO relies largely..

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Safety and feasibility of conversion from venoarterial to venovenous extracorporeal membrane oxygenation in pediatric patients: A case series

Abstract Introduction In children requiring venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for long durations, conversion to venovenous (VV) support may be advantageous. The purpose of this study was to evaluate..

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Post-Cardiac Arrest Care in Extracorporeal Cardiopulmonary Resuscitation

Abstract OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) serves as a lifesaving intervention for patients experiencing refractory cardiac arrest. With its expanding usage, there’s a burgeoning focus on improving patient outcomes through..

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“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract IMPORTANCE:  “Awake” cannulation for venovenous extracorporeal membrane oxygenation (ECMO), where patients remain spontaneously breathing without invasive mechanical ventilation during the cannulation procedure, may reduce lung injury from positive pressure..

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CIRBP Aggravation of Cardiac Fibrosis after Myocardial Infarction during ECMO Assistance

Abstract Background: Cold-induced RNA binding protein (CIRBP) is widely involved in critical physiological processes of myocardial fibrosis (MF), a crucial mechanism of cardiac insufficiency in myocardial infarction (MI). However, whether CIRBP..

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Systemic Inflammatory Responses in ECMO-Treated Patients: A Systematic Reviews and Meta-Analysis

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is associated with significant inflammatory reactions that can impact patient outcomes. This meta-analysis aimed to evaluate the impact of ECMO on the functional ability of..

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Hemodynamic Effect of Hydroxocobalamin During Extracorporeal Membrane Oxygenation

Abstract Background: Hydroxocobalamin increases systemic blood pressure through nitric oxide pathway suppression. However, its effects on hypotension during extracorporeal membrane oxygenation (ECMO) are unknown. The objective of this study was to..

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The Impact of Cannulation Sites on Post-Cardiotomy ECMO Outcomes

Abstract Introduction: Although post-cardiotomy extracorporeal membrane oxygenation (ECMO) is associated with high mortality1, the impact of cannulation site is poorly understood. Methods: We conducted a retrospective review of our post-cardiotomy veno-arterial ECMO..

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Cardiopulmonary bypass and VA-ECMO induced immune dysfunction: common features and differences, a narrative review

Abstract Cardiopulmonary bypass (CPB) and veno-arterial extracorporeal membrane oxygenation are critical tools in contemporary cardiac surgery and intensive care, respectively. While these techniques share similar components, their application contexts differ,..

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Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study

Abstract Extracorporeal circulation (ECC) is frequently implemented in a vast array of modalities such as hemodialysis, cardiopulmonary bypass, extracorporeal membrane oxygenation (ECMO), and others. Patients receiving any such therapy are..

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Adult ECMO Re-cannulation: Fruitful or Futile?

Abstract Introduction: Although decannulation from ECMO is usually irrevocable, in rare circumstances, ECMO will be reinitiated. Data on outcomes after re-cannulation of ECMO are limited,1 so we studied our experience with ECMO..

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Hospital-level volume in extracorporeal membrane oxygenation cases and death or disability at 6 months

Abstract Objective Extracorporeal membrane oxygenation (ECMO) is a high-risk procedure with significant morbidity and mortality and there is an uncertain volume-outcome relationship, especially regarding long-term functional outcomes. The aim of..

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Escalation from IABP to ECMO is associated with increased mortality in patients undergoing VA-ECMO

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used for refractory cardiogenic shock (CS). Although guidelines have downgraded the recommendations for intra-aortic balloon pump (IABP) in CS, escalation from..

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Predictors of Neurologic Complications and Neurodevelopmental Outcome in Pediatric Cardiac Surgery With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an important intervention for children both preceding and following cardiac surgery. There is a notable lack of comprehensive information regarding neurodevelopmental outcomes...

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VA-ECMO as a Bridge to Recovery in Refractory Circulatory Failure due to Bupropion Overdose

Abstract We present a case of successfully treating an adult woman with a lethal bupropion overdose with VA-ECMO. The patient presented to the hospital with severe encephalopathy, which progressed to..

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Using machine learning to predict neurologic injury in venovenous extracorporeal membrane oxygenation recipients: An ELSO Registry analysis

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with acute brain injury (ABI), including central nervous system (CNS) ischemia (defined as ischemic stroke or hypoxic-ischemic brain injury [HIBI]) and..

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Unraveling the Blood Biomaterial Interaction During Extracorporeal Membrane Oxygenation

Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports. The utilization..

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Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Abstract When native blood flow through the aorta from the adult heart and lungs meets retrograde blood flow from an artificial heart and lung during venoarterial extracorporeal membrane oxygenation (VA-ECMO),..

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