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Escalation from IABP to ECMO is associated with increased mortality in patients undergoing VA-ECMO

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used for refractory cardiogenic shock (CS). Although guidelines have downgraded the recommendations for intra-aortic balloon pump (IABP) in CS, escalation from..

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Predictors of Neurologic Complications and Neurodevelopmental Outcome in Pediatric Cardiac Surgery With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an important intervention for children both preceding and following cardiac surgery. There is a notable lack of comprehensive information regarding neurodevelopmental outcomes...

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VA-ECMO as a Bridge to Recovery in Refractory Circulatory Failure due to Bupropion Overdose

Abstract We present a case of successfully treating an adult woman with a lethal bupropion overdose with VA-ECMO. The patient presented to the hospital with severe encephalopathy, which progressed to..

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Using machine learning to predict neurologic injury in venovenous extracorporeal membrane oxygenation recipients: An ELSO Registry analysis

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with acute brain injury (ABI), including central nervous system (CNS) ischemia (defined as ischemic stroke or hypoxic-ischemic brain injury [HIBI]) and..

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Unraveling the Blood Biomaterial Interaction During Extracorporeal Membrane Oxygenation

Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports. The utilization..

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Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Abstract When native blood flow through the aorta from the adult heart and lungs meets retrograde blood flow from an artificial heart and lung during venoarterial extracorporeal membrane oxygenation (VA-ECMO),..

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Factors Influencing Successful Weaning From Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract With advancements in  (ECLS) technologies, venoarterial  (VA-ECMO) has emerged as a crucial cardiopulmonary support mechanism. This review explores the significance of VA-ECMO system configuration,  strategies, and timing of initiation. Through an analysis..

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High Risk ECMO Cannula to Circuit Connection

Abstract A patient with a percutaneously inserted cardiopulmonary bypass cannula into the right internal jugular vein, connected to an extracorporeal membrane oxygenation (ECMO) circuit using tape, was referred for transport..

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Extracorporeal membrane oxygenation support in adult patients: Comparing COVID-19- and non-COVID-19-associated respiratory failure

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a vital intervention for acute respiratory distress syndrome (ARDS), yet its efficacy with coronavirus disease 2019 (COVID-19) remains unknown. This study compared the..

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Post-discharge health-related quality of life, cognitive function, disability, risk of post-traumatic stress disorder, and depression amongst the survivors of veno-venous…

Abstract Background Veno-venous extra-corporeal membrane oxygenation (VV-ECMO) is a form of mechanical respiratory support for critically ill patients with severe acute respiratory distress syndrome (ARDS). Using a large intravenous line in..

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Ultra-Low-Field Portable MRI and Extracorporeal Membrane Oxygenation: Preclinical Safety Testing

Abstract CONTEXT:  Conventional MRI is incompatible with extracorporeal membrane oxygenation (ECMO) cannulas and pumps. Ultra-low-field portable MRI (ULF-pMRI) with 0.064 Tesla may provide a solution, but its safety and compatibility..

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Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation

Abstract In recent decades, the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has increased. In acute cardiogenic shock, VA-ECMO implantation can serve as a bridging solution to facilitate recovery, provide..

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Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction

Abstract Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group [, ]...

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Systematic Review of Ex Vivo and In Vivo Pharmacokinetic Studies of Drugs Commonly Used During Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a lifesaving treatment for critically ill patients in cardiac or respiratory failure refractory to conventional treatment. Patients on an ECMO circuit (pump, oxygenator, tubing)..

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Awake VA-ECMO: Patient characteristics and outcomes from a single center experience

Abstract Background: Veno-Arterial Extracorporeal membrane oxygenation (VA-ECMO) provides temporary cardiopulmonary support in the setting of refractory cardiogenic shock. Mechanical ventilation and sedation often accompanies VA-ECMO support and carry the increased risk..

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Association Between Tidal Volume in Invasive Mechanical Ventilation and Mortality in Children With Extracorporeal Membrane Oxygenation

Abstract Mechanical ventilation (MV) strategies in children on extracorporeal membrane oxygenation (ECMO) have not been studied much and the ventilatory parameters to avoid greater lung damage are still unclear. Our..

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My echo checklist in venoarterial ECMO patients

Abstract Transthoracic echocardiography is an essential tool for the management of venoarterial extracorporeal membrane oxygenation (VA-ECMO). Its ease of access makes it ideally suited for routine daily bedside assessments, which..

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HeartMate III Autonomy Assistant in a Hemiplegic Left Ventricular Assist Device Patient: A Case Report

Abstract Terminal heart failure presents challenges, requiring cardiac transplantation, or mechanical circulatory support. Limited donor organ availability has made mechanical support crucial. Advances in centrifugal-flow systems, compared to axial-flow, have..

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Neurosurgical Procedures in Patients Requiring Extracorporeal Membrane Oxygenation

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is often withheld in patients with significant neurologic injury or recent neurosurgical intervention due to perceived futility. Studies of neurosurgical interventions before or during..

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Extracorporeal Membrane Oxygenation Support in Adult Patients with Calcium Channel Blocker Toxicity - An ELSO Registry Analysis

Abstract Background: Calcium channel blocker (CCB) toxicity presents a significant mortality risk, highlighting the need for effective treatment strategies such as ECMO. This study analyzes ELSO registry data to determine the..

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Functional and Social Recovery and Outcomes After Extracorporeal Membrane Oxygenation Support in COVID-19 Patients

Abstract With the COVID pandemic, veno-venous (VV) extracorporeal membrane oxygenation (ECMO) was implanted in many patients around the world. Data regarding follow-up and recovery of patients who are placed on..

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Awake insertion of transplant-bridging veno-arterial extracorporeal membrane oxygenation in a shocked patient with severe thrombocytopenia: a case report.

Abstract Background: Extracorporeal membrane oxygenation is an effective life support technology in treating patients with cardiorespiratory failure. It could be used as a bridge to recovery, potentially improving patient outcomes due..

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Multiple Pediatric Extracorporeal Membrane Oxygenation Runs and Futility. What Are the Limits?

Abstract Despite high mortality rates, pediatric extracorporeal membrane oxygenation (ECMO) redeployments are frequently discussed in everyday clinical care. We aim to investigate predictors of mortality in those patients. Clinical data..

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An endothelium membrane mimetic antithrombotic coating enables safer and longer extracorporeal membrane oxygenation application

Abstract Thrombosis and plasma leakage are two of the most frequent dysfunctions of polypropylene (PP) hollow fiber membrane (PPM) used in extracorporeal membrane oxygenation (ECMO) therapy. In this study, a..

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VA-ECMO as a support therapy in massive acute pulmonary embolism treated with catheter-directed thrombolysis

Abstract Introduction: Acute pulmonary embolism (PE) leads to increased pulmonary vascular resistance and right ventricular afterload, resulting in right ventricular dysfunction (RVD). Stratification is crucial to early identify patients with elevated..

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Acquired antithrombin deficiency in adult patients with postcardiotomy extracorporeal membrane oxygenation

Abstract Introduction This study aimed to investigate the relationship between acquired antithrombin deficiency in patients undergoing postcardiotomy extracorporeal membrane oxygenation (PC-ECMO) and thromboembolic or haemorrhagic events such as bleeding, peripheral..

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support. Yet, few data are avail-able to support..

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The Role of Veno-Arterial Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism: A Case Report

Abstract Introduction: Amniotic fluid embolism (AFE) is a catastrophic complication of pregnancy with high mortality rate. It is an inflammatory response leading to cardiovascular collapse. We present a case of successful..

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Hemodynamic Effects and Clinical Outcomes of Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO) in Cardiogenic Shock

Abstract Background: Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting via a multi-fenestrated..

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“Not an ECMO Candidate”: An exploratory analysis of patients declined for VA-ECMO

Abstract Background: Patient selection for extracorporeal membrane oxygenation (ECMO) support is complex and associated with variability between clinicians. Disparities exist in ECMO use, with lower utilization in patients who are female,..

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