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Hemodynamic considerations of ipsilateral versus contralateral cannulation with venoarterial extracorporeal membrane oxygenation

Abstract Objective Patients on venoarterial extracorporeal membrane oxygenation undergoing ipsilateral cannulation may develop distal limb ischemia. We postulate 2 clinical questions: (1) Would contralateral cannulation have a lower distal limb..

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Preoperative Extracorporeal Membrane Oxygenation as a Bridge to Cardiac Surgery: Outcomes and Challenges

Abstract Background Outcomes of postcardiotomy extracorporeal membrane oxygenation (ECMO) are well studied, but preoperative ECMO bridging is less studied. This single-center review evaluates outcomes of patients supported with ECMO as..

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Implantation of integrated magnetically levitated biventricular assist devices (DuoCor) – a single-center clinical experience

Abstract Background:  End-stage heart failure remains a major global health challenge with high mortality. While heart transplantation is the gold-standard treatment, the scarcity of donor hearts necessitates alternative therapies. Left..

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Feasibility of Veno-Venous Extracorporeal Membrane Oxygenation Cannulation via the Neck in a Patient With Spinal Cord Injury Wearing a Halo…

Abstract To our knowledge, no previous reports have described the use of veno-venous extracorporeal membrane oxygenation (V-V ECMO) in patients wearing a halo vest. We present a case in which..

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Cardiac index, SvO2 or pCO2 gap may determine benefit from ECMO in cardiogenic shock: post-hoc analysis of the multicenter, randomized…

Abstract Background Immediate initiation of extracorporeal membrane oxygenation (ECMO) has not demonstrated benefit in individuals diagnosed with cardiogenic shock based on the presence of hypotension. The relationship between other hemodynamic..

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Specialized Tilt Bed for Mobilization on Femoral Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Cohort Analysis

Abstract Mobilization of patients supported on extracorporeal membrane oxygenation (ECMO)—especially with femoral cannulas—presents unique challenges. This single-center retrospective cohort study aims to assess the efficacy and safety of mobilizing these..

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Prevalence and Predictors of 3 Vital Outcomes After Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Predictors of death resulting from extracorporeal membrane oxygenation (ECMO) withdrawal, in-hospital death after ECMO liberation, and survival to hospital discharge have been evaluated incompletely, despite the prognostic insight..

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Variability in Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: An International Survey

Abstract Objective:  To characterize the variability in venovenous extracorporeal membrane oxygenation (VV-ECMO) candidacy decision-making processes across international Extracorporeal Life Support Organization (ELSO) member institutions. Design:  An international survey study of..

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Prophylactic VA-ECMO During Complex High-Risk PCI: A Randomized Controlled Trial

Abstract Background Evidence on prophylactic venoarterial extracorporeal membrane oxygenation (VA-ECMO) during elective percutaneous coronary intervention (PCI) in patients with complex high-risk coronary artery lesions is limited. Objectives The authors aimed..

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Prolonged Mechanical Ventilation Prior to Venovenous Extracorporeal Membrane Oxygenation and In-Hospital Mortality in Patients With Acute Respiratory Distress Syndrome

Abstract OBJECTIVES:  To evaluate the relationship between the duration of pre-extracorporeal membrane oxygenation (ECMO) mechanical ventilation and mortality in acute respiratory distress syndrome (ARDS) patients undergoing venovenous ECMO. DESIGN:  Retrospective..

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Cerebrovascular Strokes During Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving mechanical support in patients with cardiogenic shock. There are great variations in the reported rates of neurological complications and associated..

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Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes

Abstract Objectives:  To report on 5-year survival, health-related quality of life (HRQoL), and occupational status of patients with respiratory or cardiac failure, who were supported with extracorporeal membrane oxygenation (ECMO)...

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Construction of a nomogram model for individualized prediction of extracorporeal membrane oxygenation weaning outcomes in cardiogenic shock

Abstract Objective To construct a nomogram prediction model for death in patients with cardiogenic shock after extracorporeal membrane oxygenation (ECMO) weaning. Methods Totally 210 patients with cardiogenic shock treated with..

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Predictivity of Each Readiness-to-Explant Criterion for Successful Venoarterial Extracorporeal Membrane Oxygenation Explantation

Abstract Background: The use of temporary mechanical circulatory support (tMCS) has revolutionized the management of cardiogenic shock (CS). However, standardized readiness-to-explant criteria for venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not been..

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Extracorporeal Membrane Oxygenation in Adults with Congenital Heart Disease: Considerations, Cannulation and Challenges for Complex Cardiac Anomalies

Abstract As survival among patients with congenital heart disease (CHD) continues to improve, the population of adults with CHD (ACHD) is rapidly growing. These patients often present with complex anatomy,..

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Novel heat exchanger in extracorporeal circuit: technical and biological feasibility

Abstract To evaluate a novel anticoagulation strategy in an extracorporeal circuit, we introduce a device that induces local hypothermia as blood flows through the circuit. Using a pig model, we..

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Cardiovascular Physiology During Mechanical Circulatory Support: Implications for Management and Monitoring

Abstract Background/Objectives: Mechanical circulatory support (MCS) is increasingly utilized for the management of acute decompensated heart failure (HF) and cardiogenic shock (CS). The primary goals of MCS are to restore systemic..

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A nitric oxide-releasing organic selenium-grafted phosphorylcholine coating for thrombosis and inflammation prevention in extracorporeal membrane oxygenation

Abstract Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between these two pathological..

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Flow monitoring of venovenous and venoarterial ECMO to detect circuit obstructions using hemodynamic modeling

Abstract Introduction Current extracorporeal membrane oxygenation (ECMO) monitoring methods for circuit obstructions have limitations. In this study, we test the hypothesis that changes in flow in a pre-existing shunt tubing..

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Impact of early PaCO2 and pH fluctuations on neurological outcomes in ARDS patients receiving VV ECMO: a retrospective cohort study…

Abstract Background Neurological complications significantly contributed to mortality in patients with acute respiratory distress syndrome (ARDS) supported by venovenous extracorporeal membrane oxygenation (VV ECMO). Early fluctuations in arterial partial pressure..

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Trends and outcomes of cardiac arrest and extracorporeal membrane oxygenation during the COVID-19 pandemic in the United States

Abstract Background The COVID-19 Pandemic challenged the healthcare system worldwide, but its effect on outcomes of cardiac arrest (CA) and extracorporeal membrane oxygenation (ECMO) use are understudied. We examined trends..

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Early Exposure to Arterial Hyperoxia During Extracorporeal Membrane Oxygenator Support and Acute Brain Injury and Mortality in Patients With Cardiogenic…

Abstract BACKGROUND:  Patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) are frequently managed with varying degrees of hyperoxia. Existing data suggest that higher levels of Pao2 correlate with worsened outcome in patients..

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“Safety of ECMO Cannulation: Organization and Standardized Training Matters”

Abstract We appreciate the insightful remarks by Sin et al regarding our systematic review and meta-analysis on extracorporeal membrane oxygenation (ECMO) cannulation by intensivists. Their comments highlight important considerations for..

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Novel use of negative pressure ventilation for weaning of venovenous extracorporeal membrane oxygenation

Abstract Negative pressure ventilation (NPV) has been used to assist patients with respiratory failure. Venovenous extracorporeal membrane oxygenation (V-V ECMO) supports patients with acute lung injury who do not respond..

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Death and new disability following bleeding complications during venoarterial extracorporeal membrane oxygenation. A prospective cohort study from the EXCEL registry

Abstract Introduction Bleeding events are common during the provision of Venoarterial ECMO (VA ECMO). Previous observational has suggested that these bleeding events are associated with an increased risk of in-hospital..

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Indications and outcomes of extracorporeal life support in trauma patients

Abstract BACKGROUND  The use of extracorporeal life support (ECLS) in the trauma population remains controversial and has been reported only in small cohort studies. Recent ECLS technical advances have increased..

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The Impact of Venovenous Extracorporeal Membrane Oxygenation Cannulation Configuration on Hemodynamic Characteristics and Risks of Hemolysis

Abstract Objective To investigate the impact of veno-venous extracorporeal membrane oxygenation (VV-ECMO) cannula configuration and ECMO blood flow on intravascular hemodynamic environment, oxygen saturation, hemolysis, and thrombotic risk under varying..

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Between Hope and Harm: A Meta-Synthesis of Family Decision-Making Agonies in ECMO Initiation Crossroads

Abstract Background Family members making decisions about ECMO initiation face high-stakes uncertainty, emotional stress and cultural–ethical dilemmas. However, existing research lacks a synthesised understanding of these decision-making experiences across contexts...

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Ethical Dilemmas Surrounding ECMO Withdrawal: A Qualitative Empirical Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a critical, life-sustaining intervention often described as ‘a bridge to nowhere’ due to its transient nature and the ethical complexities it entails. This..

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Plasma Exchange in the Setting of Immune-Mediated Multiple Organ Failure in the Cardiac ICU During ECMO: A Case Series

Abstract Extracorporeal membrane oxygenation (ECMO) is a last resort treatment for children with cardio-respiratory failure. Some of these patients will develop thrombocytopenia-associated multiple organ failure (TAMOF), which is sometimes managed..

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